Selected publications

T helper 1 effector memory CD4+ T cells protect the skin from poxvirus infection
Harbour JC, Abdelbary M, Schell JB, Fancher SP, McLean JJ, Nappi TJ, Liu S, Nice TJ, Xia Z, Früh K, Nolz JC. 
Cell Rep. 2023 Apr 20

Cellular and Humoral Immune Responses in Mice Immunized with Vaccinia Virus Expressing the SARS-CoV-2 Spike Protein
Harbour JC, Lyski ZL, Schell JB, Thomas A, Messer WB, Slifka MK, Nolz JC
J. Immunol. 2021 Jun 1;206(11):2596-2604

Vaccinia virus vectors targeting peptides for MHC-II presentation to CD4+ T cells.
Hobbs SJ, Harbour JC, Yates PA­­, Ortiz, D, Landfear SM, Nolz JC
Immunohorizons. 2020 Jan 2;4(1):1-13

Control of memory CD8+ T cell longevity and effector functions by IL-15.
Nolz JC, Richer MJ
Mol Immunol. 2020 Jan;117:180-188.  Review. 

Targeted expansion of tissue-resident CD8+ T cells to boost cellular immunity in the skin.
Hobbs SJ, Nolz JC
Cell Rep. 2019 Dec 3;29(10):2990-2997

Central memory CD8+ T cells become CD69+ tissue resident during viral skin infection independent of CD62L-mediated lymph node surveillance.
Osborn JF, Hobbs SJ, Mooster JL, Khan TN, Kilgore AM, Harbour JC, Nolz JC
PLOS Pathog. 2019 Mar 15;15(3)

Activation and trafficking of CD8+ T cells during viral skin infection: immunological lessons learned from vaccinia virus.
Hobbs SJ, Osborn JF, Nolz JC
Curr Opin Virol. 2018 Feb (28):12-19. Review.

Enzymatic synthesis of core 2 O-glycans governs the tissue-trafficking potential of memory CD8+ T cells.
Osborn JF*, Mooster JL*, Hobbs SJ, Munks MW, Barry C, Harty JT, Hill AB, Nolz JC
*These Authors Contributed Equally
Sci Immunol. 2017 Oct 13;2(16)

Regulation of T cell trafficking by enzymatic synthesis of O-glycans.
Hobbs SJ, Nolz JC.
Front Immunol. 2017 May 24 8:600.  Review.

Local antigen in non-lymphoid tissue promotes resident memory CD8+ T cell formation during viral infection.
Khan TN, Mooster JL, Kilgore AM, Osborn JF, Nolz JC. 
J Exp Med. 2016 May 30;213(6):951-66

Molecular mechanisms of CD8+ T cell trafficking and localization.
Nolz JC. 
Cell Mol Life Sci. 2015 Jul;72(13):2461-73. Review.

IL-15 regulates memory CD8+ T cell O-glycan synthesis and affects trafficking.
Nolz JC, Harty JT. 
J Clin Invest. 2014. Mar 3;124(3):1013-26

Pathogen-specific inflammatory milieux tune the antigen sensitivity of CD8(+) T cells by enhancing T cell receptor signaling.
Richer MJ, Nolz JC, Harty JT. 
Immunity. 2013. Jan 24;38(1):140-52

Division-linked generation of death-intermediates regulates the numerical stability of memory CD8 T cells
Nolz JC, Rai D, Badovinac VP, Harty JT. 
Proc Natl Acad Sci U S A. 2012 Apr;109(16):6199-204

Naive, effector and memory CD8 T-cell trafficking: parallels and distinctions
Nolz JC, Starbeck-Miller GR, Harty JT. 
Immunotherapy. 2011 Oct;3(10):1223-33. Review.

Protective Capacity of Memory CD8+ T Cells Is Dictated by Antigen Exposure History and Nature of the Infection
Nolz JC, Harty JT. 
Immunity. 2011 May 27;34(5):781-93.

Strategies and Implications for Prime-Boost Vaccination to Generate Memory CD8 T Cells
Nolz JC, Harty JT. 
Adv Exp Med Biol. 2011;780:69-83. Review.