Announcements and Lab Fun
Announcements
Current Openings in the Nakai Lab
ASGCT Annual Meeting Presenters
Congratulations to the Nakai Lab members presenting at the annual ASGCT Meeting in Los Angeles (click to view abstract)
- Taisuke Furusho: Efficient Transduction in Kidney Tubules with Minimum Off-Target Effects by Renal Vein Injection of Select AAV Capsids
- Mia Galbraith-Liss: Successful Production of Monoclonal Antibodies Against Fully Assembled AAV Anc80 Capsid by a Simple DNA Vaccination Method
- Anusha Sairavi: The Potential Mechanism and Universality of the AAP Degron Model in the Process of AAV Capsid Assembly
National Junior Science and Humanities Symposium
Megan Tian, Lakeridge High School Senior
Megan was invited to give an oral presentation at the Oregon JSHS finals last month and was one of the top 5 selected to give a presentation at the National JSHS in April!
Congratulations!!!
Career Innovation Excellence Award
Hiroyuki Nakai, M.D., Ph.D.
Professor, Department of Molecular and Medical Genetics and Department of Molecular Microbiology and Immunology, School of Medicine
Distinguished Professor in Molecular Medicine, School of Medicine
The Career Innovation Excellence Award is presented to an OHSU employee who over the course of their career has demonstrated to be an accomplished inventor and entrepreneur, has shown a true passion for innovation, has been successful in engaging and cultivating partnerships with industry, and has worked tirelessly to translate their discoveries into solutions for real-world problems and the benefit of society.
Pioneering research from the laboratory of Dr. Nakai is focused on understanding adeno-associated virus (AAV) vectors and developing new AAV vector-mediated gene and cell therapies to treat various human diseases. The laboratory takes an impressively broad multi-disciplinary approach, using molecular, cellular and structural biology techniques, bioinformatics, computational biology, computer simulation, various high-throughput technologies including DNA and RNA barcoding, next-generation sequencing (NGS), and mass spectrometry.
Nakai’s research has led to the authorship of over 70 publications, including high impact journals of Nature and PNAS, and 23 technology disclosures since joining OHSU in 2011. In the past few years, a number of Nakai’s technologies were licensed to form the basis of a new startup company, Capsigen. Within their first year of operation Capsigen secured a large strategic research collaboration with Biogen, to engineer novel AAV capsids that have the potential to deliver transformative gene therapies that address the underlying genetic causes of various CNS and neuromuscular disorders.
Congratulations!!!
American Society of Gene & Cell Therapy Award
Anusha Sairavi, M.S.
Congratulations to Anusha Sairavi for earning a Meritorious Abstract Travel Award from the American Society of Gene & Cell Therapy (ASGCT) for her oral presentation on the topic
"Genome Packaging Efficiencies of Anc80 and AAV9 Vectors using Non-canonical Rep-ITR Combinations".
Keep Up the Great Work!
Recently Published Papers (by current and former members of Nakai Lab)
ASE Symposium Presentation (Megan Tian & Menaka Wijeratne)
Nakai Lab ASE interns speak at the ASE Symposium "Machine learning, guided design of novel adeno-associated viruses AAV vectors for human gene therapy"
Click on link to view talk:
Lab Fun
April, 2022
