Selected publications

Characterization of the Herpes Simplex Virus (HSV) Tegument Proteins That Bind to gE/gI and US9, Which Promote Assembly of HSV and Transport into Neuronal Axons. 
DuRaine G, Wisner TW, Johnson DC.
J Virol. 2020 Nov 9;94(23):e01113-20. doi: 10.1128/JVI.01113-20. Print 2020 Nov 9.
PMID: 32938770

Cryo-Electron Microscopy Structure and Interactions of the Human Cytomegalovirus gHgLgO Trimer with Platelet-Derived Growth Factor Receptor Alpha
Jing Liu, Adam Vanarsdall, Dong-hua Chen, Andrea Chin, David Johnson, Theodore S. Jardetzkya
mBio. 2021 Nov 10; 10.1128/mBio.02625-21

Characterization of the herpes simplex virus tegument proteins that bind to gE/gI and US9, which promote assembly of HSV and transport into neuronal axons.
DuRaine G, Wisner TW, Johnson DC.
J Virol. 2020 Sep 16:JVI.01113-20. doi: 10.1128/JVI.01113-20.
PMID: 32938770

HCMV trimer- and pentamer-specific antibodies synergize for virus neutralization but do not correlate with congenital transmission.
Vanarsdall AL, Chin AL, Liu J, Jardetzky TS, Mudd JO, Orloff SL, Streblow D, Mussi-Pinhata MM, Yamamoto AY, Duarte G, Britt WJ, Johnson DC.
Proc Natl Acad Sci U S A. 2019 Feb 26;116(9):3728-3733. doi: 10.1073/pnas.1814835116. Epub 2019 Feb 7.
PMID: 30733288 

CD147 Promotes Entry of Pentamer-Expressing Human Cytomegalovirus into Epithelial and Endothelial Cells.
Vanarsdall AL, Pritchard SR, Wisner TW, Liu J, Jardetzky TS, Johnson DC.
mBio. 2018 May 8;9(3):e00781-18. doi: 10.1128/mBio.00781-18.
PMID: 29739904

Kinesin-1 Proteins KIF5A, -5B, and -5C Promote Anterograde Transport of Herpes Simplex Virus Enveloped Virions in Axons.
DuRaine G, Wisner TW, Howard P, Johnson DC.
J Virol. 2018 Sep 26;92(20):e01269-18. doi: 10.1128/JVI.01269-18. Print 2018 Oct 15.
PMID: 30068641 

Herpes Simplex Virus gE/gI and US9 Promote both Envelopment and Sorting of Virus Particles in the Cytoplasm of Neurons, Two Processes That Precede Anterograde Transport in Axons.
DuRaine G, Wisner TW, Howard P, Williams M, Johnson DC.
J Virol. 2017 May 12;91(11). pii: e00050-17. doi: 10.1128/JVI.00050-17. Print 2017 Jun 1.
PMID: 28331094

Human Cytomegalovirus gH/gL Forms a Stable Complex with the Fusion Protein gB in Virions.
Vanarsdall AL, Howard PW, Wisner TW, Johnson DC.
PLoS Pathog. 2016 Apr 15;12(4):e1005564. doi: 10.1371/journal.ppat.1005564. eCollection 2016 Apr.
PMID: 27082872  

Herpes simplex virus gE/gI extracellular domains promote axonal transport and spread from neurons to epithelial cells.
Howard PW, Wright CC, Howard T, Johnson DC.
J Virol. 2014 Oct;88(19):11178-86. doi: 10.1128/JVI.01627-14. Epub 2014 Jul 16.
PMID: 25031334  

Human cytomegalovirus (HCMV) glycoprotein gB promotes virus entry in trans acting as the viral fusion protein rather than as a receptor-binding protein.
Wille PT, Wisner TW, Ryckman B, Johnson DC.
MBio. 2013 Jun 4;4(3):e00332-13. doi: 10.1128/mBio.00332-13.
PMID: 23736286  

HCMV gB shares structural and functional properties with gB proteins from other herpesviruses.

Sharma S, Wisner TW, Johnson DC, Heldwein EE.
Virology. 2013 Jan 20;435(2):239-49. doi: 10.1016/j.virol.2012.09.024. Epub 2012 Oct 22.
PMID: 23089254  

Herpes simplex virus membrane proteins gE/gI and US9 act cooperatively to promote transport of capsids and glycoproteins from neuron cell bodies into initial axon segments.
Howard PW, Howard TL, Johnson DC.
J Virol. 2013 Jan;87(1):403-14. doi: 10.1128/JVI.02465-12. Epub 2012 Oct 17.
PMID: 23077321  

PDGF receptor-α does not promote HCMV entry into epithelial and endothelial cells but increased quantities stimulate entry by an abnormal pathway.
Vanarsdall AL, Wisner TW, Lei H, Kazlauskas A, Johnson DC.
PLoS Pathog. 2012 Sep;8(9):e1002905. doi: 10.1371/journal.ppat.1002905. Epub 2012 Sep 13.
PMID: 23028311  

Herpes simplex virus glycoproteins gB and gH function in fusion between the virion envelope and the outer nuclear membrane.
Aaron Farnsworth, Todd W. Wisner, Michael Webb, Richard Roller, Gary Cohen, Roselyn Eisenberg, and David C. Johnson. 
(2007) PNAS 104(24), 10187-10192.

Human Cytomegalovirus Entry into Epithelial and Endothelial Cells Depends on Genes UL128 to UL150 and Occurs by Endocytosis and Low-pH Fusion. 
Brent J. Ryckman, Michael A Jarvis, Derek D. Drummond, Jay A. Nelson, and David C. Johnson.
J. Virol. 2006 80: 710-722.

The Role of BiP in Endoplasmic Reticulum-associated Degradation of Major Histocompatibility Complex Class I Heavy Chain Induced by Cytomegalovirus Proteins. 
Nagendra R. Hegde, Mathieu S. Chevalier, Todd W. Wisner, Michael C. Denton, Kathy Shire, Lori Frappier, and David C. Johnson. 
J Biol Chem. 2006 Jul 28;281(30):20910-9. Epub 2006 May 25.

Herpes keratitis in the absence of anterograde transport of virus from sensory ganglia to the cornea.
Katarina Polcicova, Partha Sarathi Biswas, Kaustuv Banerjee, Todd W. Wisner *, Barry T. Rouse, and David C. Johnson.
(2005) PNAS 102(32), 11462-11467. 

Endogenous human cytomegalovirus gB is presented efficiently by MHC class II molecules to CD4+ CTL.
Nagendra R. Hegde, Claire Dunn, David M. Lewinsohn, Michael A. Jarvis, Jay A. Nelson, and David C. Johnson. 
J. Exp. Med., Oct 2005; 202: 1109 - 1119.