Publications with core data since 2004:

  1. DeBarber A. E., Bleyle L, Roullet J. B., Koop D. R., Omega-Hydroxylation of farnesol by mammalian cytochromes P450, Biochim Biophys Acta 1682: 18-27, 2004

  2. Brady, J.D., Rich, T.C., Le, X., Stafford, K., Fowler, C.J., Lynch, L., Karpen, J.W., Brown, R.L., and Martens, J.R., Functional role of lipid raft microdomains in cyclic nucleotide-gated channel activation. Mol. Pharmacol. 65: 503-511., 2004

  3. Soumyanath, A., Zhong, Y.P., Gold, S.A., Yu, X., Koop, D.R., Bourdette, D., Gold, B.G. (2005) Centella asiatica accelerates nerve regeneration upon oral administration and contains multiple active fractions increasing neurite elongation in-vitro. J Pharm Pharmacol. 57:1221-1229.

  4. Blanke, C.D., Mattek, N.C., Deloughery, T.G., Koop, D.R. (2005) A phase I study of 5-fluorouracil, leucovorin, and celecoxib in patients with incurable colorectal cancer. Prostaglandins Other Lipid Mediat. 75:169-172.

  5. Lycette, J.L., Dul, C.L., Munar, M., Belle, D., Chui, S.Y., Koop, D.R., and Nichols C.R. (2006) Effect of pregnancy on the pharmacokinetics of paclitaxel: A case report. Clin. Breast Cancer, 7:342-344.

  6. Strassmaier, T., Uma, R., Ghatpande, A.S., Bandyopadhyay, T., Schaffer, M., Witte, J., McDougal, P.G., Brown, R.L., and Karpen, J.W., Modifications to the tetracaine scaffold produce cyclic nucleotide-gated channel blockers with widely varying efficacies. J. Med. Chem. 48: 5805-5812., 2005

  7. Alice, A.F., Lopez, C.S., Lowe, C.A., Ledesma, M.A., and Crosa, J.H., Genetic and transcriptional analysis of the sideropohore malleobactin biosynthesis and transport genes in the human pathogen Burkholderia pseudomallei K96243. J. Bacteriol. 188: 1551-1566, 2006.

  8. Palaniappan, N., Ayers,S., Gupta, S., Habib E.–S, and Reynolds, K. A., Production of hygromycin A analogues in Streptomyces hygroscopicus NRRL 2388 through identification and manipulation of the biosynthetic gene cluster. Chem. Biol., 13: 753-64, 2006.

  9. Strassmaier, T., and Karpen, J.W., Novel N7- and N1-substituted cGMP derivatives are potent activators of cyclic nucleotide-gated channels. J. Med. Chem. 50: 4186-4194, 2007

  10. Wadsworth, T.L., Worstell, T.R., Greenberg, N.M. and Roselli, C.E., Effects of dietary saw palmetto on the prostate of transgenic adenocarcinoma of the mouse prostate model (TRAMP). Prostate, 67: 661-673, 2007.

  11. Koerner, I., Grant, D., DeBarber, A., Koop, D.R., Alkayed, N.,  Polymorphisms in the Human Soluble Epoxide Hydrolase Gene EPHX2 Linked to Neuronal Survival after Ischemic Injury, J Neuroscience, 27:4642-4649, 2007.

  12. Chiellini G, Frascarelli S, Ghelardoni S, Carnicelli V, Tobias SC, DeBarber A, Brogioni S, Ronca-Testoni S, Cerbai E, Grandy DK, Scanlan TS, Zucchi R. Cardiac effects of 3-iodothyronamine: a new aminergic system modulating cardiac function. FASEB J. 2007 May;21(7):1597-608. Epub 2007 Feb 6.

  13. Braulke LJ, Klingenspor M, DeBarber A, Tobias SC, Grandy DK, Scanlan TS, Heldmaier G. 3-Iodothyronamine: a novel hormone controlling the balance between glucose and lipid utilisation.  J Comp Physiol B. 2008 Feb;178(2):167-77. Epub 2007 Oct 3.

  14. Alhamadsheh, M. M., Palaniappan, N., DasChouduri, S., and Reynolds KA. Modular Polyketide Synthases and cis-Double Bond Formation: Establishment of Activated cis-3-Cyclohexylpropenoic Acid as the Diketide Intermediate in Phoslactomycin Biosynthesis. J. Amer. Chem. Soc. 129: 1910-1, 2007.

  15. Strassmaier, T., Kirk, S.R., Banerji, T., and Karpen, J.W., 2008. Block of cyclic nucleotide-gated channels by tetracaine derivatives: Role of apolar interactions at two distinct locations. Bioorg. Med. Chem. Lett. 18: 645-649. 2008.

  16. McDougall, S.J.; Bailey, T.W.; Mendelowitz, D; Andresen, M.C. Propofol enhances both tonic and phasic GABAA transmission onto second-order neurons of the solitary tract nucleus (NTS). Neuropharmacology, 54:552-563, 2008.

  17. Naka, H., Lopez, C.S. and Crosa, J.H. Reactivation of the vanchrobactin siderophore system of Vibrio anguillarum by removal of a chromosomal insertion sequence originated in plasmid pJM1 encoding the anguibactin siderophore system. Environ. Microbiol. 10: 265-277, 2008.

  18. Peters, J.H.; McDougall, S.J.; Mendelowitz, D; Koop, D.R.; Andresen, M.C. Isoflurane differentially modulates inhibitory and excitatory synaptic transmission to the solitary tract nucleus. Anesthesiology, April, 2008, Apr;108(4):675-83.

  19. Zhang W, Otsuka T, Sugo N, Ardeshiri A, Alhadid YK, Iliff JJ, DeBarber AE, Koop D, Alkayed NJ. Soluble Epoxide Hydrolase Gene Deletion is Protective Against Experimental Cerebral Ischemia. Stroke, 2008. Jul;39(7):2073-8. Epub 2008 Mar 27.

  20. Mo. S., Sydor, P.K., Corre, C., Alhamadsheh, M.M., Stanley, A.E., Haynes, S.W., Song, K.A. and Challis, G. L. Elucidation of the Streptomyces coelicolor pathway to 2-undecylpyrrole, a key intermediate in undecylprodiginine and streptorubin B biosynthesis Chem. Biol. 2008 Feb;15(2):137-48.

  21. DeBarber AE, Lütjohann D, Merkens L, Steiner RD. Liquid chromatography-tandem mass spectrometry determination of plasma 24S-hydroxycholesterol with chromatographic separation of 25-hydroxycholesterol  Anal Biochem. 2008 Oct 1;381(1):151-3. Epub 2008 Jun 13

  22. McDougall SJ, Peters JH, LaBrant L, Wang X, Koop DR, Andresen MC. Paired assessment of volatile anesthetic concentrations with synaptic actions recorded in vitro. PLoS One. 2008 Oct 8;3(10):e3372.

  23. DeBarber AE, Geraci T, Colasurdo VP, Hackenmueller SA, Scanlan TS. Validation of a liquid chromatography-tandem mass spectrometry method to enable quantification of 3-iodothyronamine from serum.  J Chromatogr A. 2008 Nov 7;1210(1):55-9. Epub 2008 Sep 12.

  24. Wood WJ, Geraci T, Nilsen A, DeBarber AE, Scanlan TS. Iodothyronamines are oxidatively deaminated to iodothyroacetic acids in vivo. Chembiochem. 2009 Jan 26;10(2):361-5.