Orderable EAP code:

LAB00920

Billable EAP Codes:

80005520 x 2

CPT Codes:

83883 x 2

Lab Section:

Immunology

Includes:

Kappa Quant Free Light Chains

Lambda Quant Free Light Chains

KAPPA/LAMBDA RATIO, FREE LIGHT CHAINS

Turnaround Time:

Routine: 4 days

Test Schedule:

Monday, Wednesday, and Friday 

Specimen Requirements:

2 mL blood in a GOLD top tube. Separate serum from cells ASAP or within 2 hours of collection. Send 1 mL aliquot refrigerated. 

Stability: 

Plasma is stable for 7 days refrigerated at 2-8 C

Pediatric Specimen Requirements:

Minimum volume = 0.5 mL serum 

Reference Range:

Kappa 3.30 - 19.40mg/L

Lambda 5.71 - 26.30 mg/L

Kappa:Lambda Ratio 0.26 - 1.65

Synonyms:

Free Light Chains

Kappa Qnt Free Light Chains

Kappa/Lambda Free Light Chain Ratio

Lambda Qnt Free Light Chains

Orderable EAP code:

LAB00057

Billable EAP Codes:

80003512 x 1

CPT Codes:

87305 x 1

Lab Section:

Immunology

Turnaround Time:

Routine: 3 to 5 days

Test Schedule:

Monday, Wednesday, and Friday.

Critical Values:

Positive

Specimen Requirements:

4 mL blood collected in a serum separator tube (gold SST) or serum tube (red); Send 2 aliquots of 1mL each frozen serum.

Minimum volume = 2 aliquots of 0.4 mL serum



Collect blood samples according to standard laboratory procedures. Serum samples must be uncontaminated with fungal spores and/or bacteria. Transport and store samples in sealed tubes, unexposed to air.

Unopened samples can be stored at 2-8ºC for up to 5 days prior to testing. After initial opening, serum samples may be stored at 2-8°C for 48 hours prior to testing. For longer storage, store the serum at -70ºC

Pediatric Specimen Requirements:

2 mL blood collected in a serum separator tube (gold SST) or serum tube (red);

Minimum volume = 2 aliquots of 0.4 mL serum.



Collect blood samples according to standard laboratory procedures. Serum samples must be uncontaminated with fungal spores and/or bacteria. Transport and store samples in sealed tubes, unexposed to air.



Unopened samples can be stored at 2-8ºC for up to 5 days prior to testing. After initial opening, serum samples may be stored at 2-8°C for 48 hours prior to testing. For longer storage, store the serum at -70ºC

Reference Range:

Comments:

This test has not been evaluated in neonates and reference ranges have not been established for this age group.

Negative results do not exclude the diagnosis of invasive Aspergillosis.

False negative results may be seen in patients receiving concomitant anti-fungals, and patients with chronic granulomatous disease and Jobs syndrome.

A single positive test result (index equal to or greater than 0.5) should be clinically correlated by testing a separate serum because many agents (e.g. food, antibiotics) may cross-react with the assay. False positive results may also be seen in very young children, patients with altered intestinal barrier, and patients infected with other genre of fungi such as Penicillium, Alternaria, Histoplasma, and Geotrichum.

If invasive Aspergillosis is suspected in high-risk patients, serial sampling is recommended.

Synonyms:

Aspergillus Galactomannan Antigen