Orderable EAP code:

LAB102517

Billable EAP Codes:

80001678 x 1

CPT Codes:

80200 x 1

Lab Section:

Core Lab

Turnaround Time:

Routine: 2 Hours

Urgent: 1 Hour

Test Schedule:

24 hours, 7 days a week.

Units:

mcg/mL

Specimen Requirements:

4 mL blood in a GREEN top, lithium heparin tube. Specimen to be collected 6 hours (or up to 10 hours) after the end of the infusion.

Pediatric Specimen Requirements:

0.6 mL blood in a GREEN top, lithium heparin tube. Specimen to be collected 6 hours (or up to 10 hours) after the end of the infusion.

Reference Range:

No Therapeutic Ranges established; results of 2 and 6 hour post dosing collections to be interpreted by Pharmacy.

Synonyms:

Tobramycin AUC for Cystic Fibrosis, 6 hour

Orderable EAP code:

LAB102516

Billable EAP Codes:

80001678 x 1

CPT Codes:

80200 x 1

Lab Section:

Core Lab

Turnaround Time:

Routine: 2 Hours

Urgent: 1 Hour

Test Schedule:

24 hours, 7 days a week.

Units:

mcg/mL

Specimen Requirements:

4 mL blood in a GREEN top, lithium heparin tube. Specimen to be collected 2 hours after the end of the infusion.

Pediatric Specimen Requirements:

0.6 mL blood in a GREEN top, lithium heparin tube. Specimen to be collected 2 hours after the end of the infusion.

Reference Range:

No Therapeutic Ranges established; results of the 2 and 6 hours post dosing collections to be interpreted by Pharmacy.

Synonyms:

Tobramycin (AUC) for Cystic Fibrosis 2 hour

Orderable EAP code:

LAB01051

Billable EAP Codes:

80001660 x 1 80001661 x 1 80001662 x 1 80001663 x 1 80001664 x 1 80002914 x 1 80002915 x 1 80005610 x 1

CPT Codes:

80307 x 8

Lab Section:

Core Lab

Includes:

Amphetamines, Benzodiazepines, Cannabinoids, Cocaine, Opiate, Oxycodone, Methadone, Fentanyl

Turnaround Time:

Routine: 2 Hours

Urgent: 1 Hour

Test Schedule:

24 hours, 7 days a week.

Specimen Requirements:

6 mL urine cup.

Reference Range:

Negative

Comments:

"Positive" results are not confirmed by an alternate method. See: Summary of Compounds that may be detected by OHSU Drugs of Abuse Screening Methods. (Opens in a new window)

Synonyms:

Drug Screen, Chronic Pain, Pain Clinic Drug Screen, Urine Drug Screen

Orderable EAP code:

LAB01026

Billable EAP Codes:

80003550 x 1

CPT Codes:

87653 x 1

Lab Section:

Core Lab

Turnaround Time:

Routine: 4 Hours

Urgent: 2 Hours

Test Schedule:

24 hours, 7 days a week.

Interpretation:

Pos, Neg, or Indeterminate. If positive, and patient has a documented allergy to penicillin/cephalosporins, a reflex culture is performed.

Specimen Requirements:

Double swab in Liquid Stuarts.

Synonyms:

Group B Strep Screen

OB Strep Screen

Strep B DNA

Strep B OB DNA PCR

Strep B PCR

Orderable EAP code:

LAB00573

Billable EAP Codes:

80001664 x 1

CPT Codes:

80307 x 1

Lab Section:

Core Lab

Turnaround Time:

Routine: 2 Hours

Urgent: 1 Hour

Test Schedule:

24 hours, 7 days a week.

Specimen Requirements:

6 mL urine in sample cup.

Pediatric Specimen Requirements:

6 mL urine in sample cup or in 10 mL RED top tube.

Reference Range:

Negative

Comments:

Detects opiates in urine at levels greater than or equal to 300 ng/mL. "Positive" results are not confirmed by alternate method. See Summary of Compounds that may be detected by OHSU Drugs of Abuse Screening Methods. (Opens in a new window)

Synonyms:

Drugs of Abuse, Opiates, Drug Screen, Urine Drug Screen, Heroin, Morphine

Orderable EAP code:

LAB101755

Billable EAP Codes:

80005342 x 1

CPT Codes:

87634 x 1

Lab Section:

Core Lab

Turnaround Time:

Routine: 4 Hours

Urgent: 2 Hours

 

Test Schedule:

24 hours, 7 days a week.

Critical Values:

All detected targets will be called.

Related Links:

Patient Fact Sheet (Oct 1, 2020) Healthcare Providers Fact Sheet (Sep 10, 2021)

Specimen Requirements:

Nasal aspirates, nasal washes or nasopharyngeal swabs in viral transport media (red capped swab kit) or phosphate buffered saline (orange capped swab kit).

BAL and tracheal aspirates in sterile, leak proof container.

Comments:

This test has not been evaluated for patients without signs and symptoms of respiratory tract infection. Zicam at 15% (w/v) may interfere with the detection of low levels of influenza B and RSV A.

The Xpert Xpress SARS-CoV-2/Flu/RSV PLUS test is a rapid, multiplexed real-time RT-PCR test intended for the detection and differentiation of SARS-CoV-2, influenza A, influenza B, and respiratory syncytial virus (RSV) viral RNA in specimens collected from individuals suspected of respiratory viral infection consistent with COVID-19.

Negative results do not preclude infection and should not be used as the sole basis for treatment or other patient management decisions. Combine results with clinical observations, patient history, and epidemiological information.

Synonyms:

RSV

Respiratory Virus Panel

RSV Antigen

Orderable EAP code:

LAB101690

Billable EAP Codes:

80001093 x 1 80001100 x 1 (if reflexed)

CPT Codes:

85250 x 1 85335 x 1 (if reflexed)

Lab Section:

Core Lab

Includes:

If factor activity level is less than 40%, an inhibitor test will be performed.

Turnaround Time:

Activity: 4 Hours.

Test Schedule:

Activity: 24 hours, 7 days a week. 

Inhibitor: batched twice per week. 

Units:

Factors: %; Inhibitors: Bethesda Units (BU)

Specimen Requirements:

3.2% 2 to 2.7 mL blood in a LIGHT BLUE top tube, 3.2% sodium citrate.

3.2% sodium citrate tubes are acceptable when they are filled to the line on the manufacturers label. Tubes must be full (see comments below). For referral testing, submit 3 tubes of 1.0 mL platelet poor plasma.

Sodium citrate specimens must be processed and frozen within 2 hours of specimen collection.

OHSU Clinics must cab specimens to the Core Lab, Hatfield Research Center (HRC), Room 9D05 if processing is delayed or not possible on site. A phone call is helpful to alert the lab at 503-494-5764.

Detailed instructions are under Hemostasis & Thrombosis section (Opens in a new window).

Pediatric Specimen Requirements:

Sodium citrate tubes are acceptable when they are filled to the line on the manufacturers label.

One 2.7 mL correctly filled in an adult size LIGHT BLUE top tube, or two correctly filled 1.3 mL pediatric BLUE top tubes, 3.2% sodium citrate.

A single 1.3 mL pediatric tube may be sent but will only allow for factor activity testing; the inhibitor, if indicated, may not be performed due to insufficient plasma volume.

For pediatric patients requiring multiple coagulation tests, please call 503-494-7383 regarding draw volumes.

Reference Range:

Reference Range: 65% to 150%

Inhibitor: Less than 0.6 BU

Comments:

Draw volume is critical due to the liquid anticoagulant. Allow tubes to fill by vacuum.

• Tubes with rubber stopper: fill to line on label.
• Tubes with plastic (Hemogard) cap: the fill level is above the top of the label.
• Syringe: do not remove the vacutainer stopper. Insert the needle through the stopper and allow the tube to fill by vacuum. Do not overfill the vacutainer.
• Pediatric tubes have no vacuum. Remove the cap and add blood to the 1.3 mL mark. Do not overfill.

Avoid warfarin (Coumadin) therapy for two weeks and heparin therapy for 2 days prior to the test.

Inhibitors to factor IX arise in about 3% of persons with severe hemophilia B, which is less common that the incidence of inhibitors to factor VIII in persons with severe hemophilia A. In both types of hemophilia, most inhibitors arise early in life, after only a few injections of the missing clotting factor.

Inhibitors to factor IX are sometimes more dangerous than those to factor VIII. The reaction between factor VIII and its inhibitor-antibody does not cause symptoms. The reaction between factor IX and its inhibitor-antibody may cause severe allergic reactions which can be life-threatening (so-called "anaphylactic reactions"). Such reactions may occur with the very first infusion of factor IX after an inhibitor has developed - before anyone is aware that an inhibitor has arisen. All inhibitors in hemophilia B do not cause allergic reactions on exposure to more factor IX. Development of an inhibitor to factor IX can be predicted, at least in part, by determining the kind of factor IX gene mutation the baby has.

Methodology: clotting, Bethesda assay.

Synonyms:

Factor 9

Inhibitor

FIX

Orderable EAP code:

LAB101689

Billable EAP Codes:

80001094 x 1 80001099 x 1 (if reflexed)

CPT Codes:

85240 x 1 85335 x 1 (if reflexed)

Lab Section:

Core Lab

Includes:

If factor activity level is less than 40%, an inhibitor test will be performed.

Turnaround Time:

Activity: 4 Hours

Test Schedule:

Activity: 24 hours, 7 days a week. 

Inhibitors: Batched twice per week. 

Units:

Factors: %; Inhibitors: Bethesda Units (BU)

Specimen Requirements:

2 to 2.7 mL blood in a LIGHT BLUE top tub, 3.2% sodium citrate.

3.2% sodium citrate tubes are acceptable when they are filled to the line on the manufacturers label. Tubes must be full (see comments below). For referral testing, submit 3 x 1.0 mL platelet poor plasma.

Sodium citrate specimens must be processed and frozen within 2 hours of specimen collection.

OHSU Clinics must cab specimens to the Core Lab, Hatfield Research Center (HRC), Room 9D05 if processing is delayed or not possible on site. A phone call is helpful to alert the lab at 503-494-5764.

Detailed instructions are under Hemostasis & Thrombosis section (Opens in a new window).

Pediatric Specimen Requirements:

One 2.7 mL correctly filled in an adult size LIGHT BLUE top tube, or two correctly filled 1.3 mL pediatric BLUE top tubes, 3.2% sodium citrate.

A single 1.3 mL pediatric tube may be sent but will only allow for factor activity testing; the inhibitor, if indicated, may not be performed due to insufficient plasma volume.

For pediatric patients requiring multiple coagulation tests, please call 503-494-7383 regarding draw volumes.

Reference Range:

Reference Range: 50% to 150%

Inhibitor: Less than 0.6 BU

Comments:

Draw volume is critical due to the liquid anticoagulant. Allow tubes to fill by vacuum.

• Tubes with rubber stopper: fill to line on label.
• Tubes with plastic (Hemogard) cap: the fill level is above the top of the label.
• Syringe: do not remove the vacutainer stopper. Insert the needle through the stopper and allow the tube to fill by vacuum. Do not overfill the vacutainer.
• Pediatric tubes have no vacuum. Remove the cap and add blood to the 1.3 mL mark. Do not overfill.

Avoid warfarin (Coumadin) therapy for two weeks and heparin therapy for 2 days prior to the test.

Assay to detect a circulating anticoagulant to factor VIII. Some patients with hemophilia A develop inhibitors to infused factor VIII, which may completely neutralize the action of the factor. In rare cases, individuals without hemophilia may also develop factor VIII inhibitors. For these patients, inhibitors result in spontaneous episodes of bleeding with no prior indication of any coagulation disorder. The action of the inhibitors differs somewhat between patients with hemophilia A and those without the disorder. Inhibitors in hemophiliacs tend to result in complete inactivation of factor VIII when enough inhibitors are present. In contrast, patients without hemophilia who develop inhibitors may still have some factor VIII activity even though the inhibitor is present. Simple vs. complex kinetics noted.

Methodology: Time-temperature dependent factor VIII assay (clotting Bethesda assay).

Synonyms:

Factor 8

Inhibitor

FVIII

Orderable EAP code:

LAB00204

Billable EAP Codes:

80001891 x 1 80001945 x 1

CPT Codes:

87207 x 1 87015 x 1

Lab Section:

Core Lab

Includes:

Thin smear, thick smear, parasitemia %

Turnaround Time:

Routine: 4 Hours

Urgent: 2 Hours

Test Schedule:

24 hours, 7 days a week.

Critical Values:

Blood parasites seen

Specimen Requirements:

3 mL fresh blood in a LAVENDER top tube.

Pediatric Specimen Requirements:

0.5 mL fresh blood in a pediatric LAVENDER top microtainer.

Reference Range:

No parasites seen.

Comments:

Preliminary identification will be made 24 hours per day. Final identification will be performed by a pathologist during business hours. Final parasite identification may require 1 to 5 business days.

Travel history is helpful for identification.

Specimen should arrive in the lab within one hour of the collection. If transport to the lab will be delayed, prepare three (3) thin blood smears (unstained, unfixed), and three (3) thick smears (unstained, unfixed) in addition to sending the whole blood tube. Thin smears are prepared in the same manner as for hematology differentials. Thick smears are made by spreading a 10 to 20 microliter drop of blood on a glass slide in a dime-sized area using a glass, plastic, or wooden applicator.

Instructions for thick and thin smears can be found here (Opens in a new window).

Synonyms:

BPA, Malaria, Thick Smear, Thin Smear

Orderable EAP code:

LAB100518

Billable EAP Codes:

80002915 x 1

CPT Codes:

80307 x 1

Lab Section:

Core Lab

Includes:

Methadone

Turnaround Time:

Routine: 2 Hours

Urgent: 1 Hour

Test Schedule:

24 hours, 7 days a week.

Specimen Requirements:

6 mL urine cup.

Pediatric Specimen Requirements:

6 mL urine in sample cup or in 10 mL RED top tube.

Reference Range:

Negative

Comments:

Methadone detected in urine at levels greater than or equal to 300 ng/mL are considered "positive". "Positive" results are not confirmed by alternate method. See: Summary of Compounds that may be detected by OHSU Drugs of Abuse Screening Methods. (Opens in a new window)

Synonyms:

Drug Screen, Urine Drug Screen