A basic science department examining cell-intrinsic and cell-extrinsic regulation of cell, developmental and cancer biology. READ ABOUT US.
WelcomeThe overarching mission of the OHSU Department of Cell, Developmental & Cancer Biology is to advance the understanding of problems relevant to human health and disease. To accomplish this mission, research groups in the department have historically focused on questions regarding cell structure, organelles, life cycle, differentiation, and regulated communication between cells and extracellular signals and cues. An ultimate application of knowledge gained from these studies has been to understand important cell physiologic processes that effect human biology. These issues directly link to problems of interest to developmental biologists, including molecular and cellular mechanisms regulating tissue morphogenesis, tissue polarity and patterning. Read more
CDCB in the news
Dr. Caroline Enns was elected to the American Association for the Advancement of Science (AAAS) this year for outstanding fundamental research discoveries on the biochemical, cell biological, and physiological mechanisms underlying iron homeostasis and its regulation. Read more.
OHSU cancer researcher aims to make cancer a manageable disease
About one in three Americans will be diagnosed with cancer in their lifetimes, and close to 600,000 will die as a result this year. Lisa Coussens hopes to dramatically reduce that number, making cancer a manageable disease instead of a deadly one. While traditional cancer research focuses on the malignant cells themselves, Coussens, a professor at the Knight Cancer Institute at the Oregon Health and Science University, is part of a new wave of biologists investigating the surrounding microenvironment. Read more.
OHSU researching new breast cancer drug
Women with the most aggressive form of breast cancer are getting some new hope from research done right here in Portland. Women with triple negative breast cancer don't usually respond to the most traditional therapies. The prognosis is also another five to eight years to live, but this new research is aiming at extending that.