Solid Tumors
Scientific Goals
One of the primary goals of the Solid Tumors Program is to conduct studies of novel diagnostics and therapeutic response monitoring, molecular targets and therapies and cancer immunology, through integration of basic, translational and clinical trials integrating specialized cell culture and animal models, translational studies of human tissue, and clinical trials, by leveraging the organizational structure and shared resources of the OHSU Knight Cancer Institute. This includes conducting preclinical investigations, using molecular methods to identify and validate new biomarkers for diagnosis and prognosis, and molecular targets for treatment and prevention of progression.
FOCUS GROUPS
There are three focus groups within the Solid Tumors Program, each one a dynamic working group that connects members doing basic/translational research to clinical members (through research forums, retreats, and seminar series, journal clubs, training grants) and to specialized research approaches, including pre-clinical (tissue and cell specific cell culture, animal models, target biochemical studies and drug development), human tissue studies (marker evaluation, treatments, imaging advances) and clinical trials (design and implementation).
- Diagnostics, Predictors and Therapeutic
- Target Development and Therapeutics
- Cancer Immunology and Immunotherapy
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cancer prostate bladder oncology |
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prostate cancer |
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Appointments: Transgenic Core Director |
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carcinogenesis novel molecular therapeutics Thyroid and Parathyroid Glands Microsurgery |
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Hematology |
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Appointments: Associate Professor |
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dynamic contrast-enhanced MRI sarcoma MRI breast cancer |
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tissue optics optical diagnostics biomedical engineering lasers |
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Appointments: Leader, Pediatric Cancer Biology Program |
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ubiquitin ligase trim32 piasy p73 |
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mouse models genomic instability colon cancer research OHSU colorectal cancer |
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Appointments: Assistant Professor, Department of Biomedical Engineering Assistant Professor, Department of Cell & Development Biology |
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Kidney and Pancreas Transplant Bile Duct Cancer Cysts Tumors Liver Liver Cancer |
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lymphocyte activation immunological tolerance immunological synapse intercellular communication |
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insulin-like growth factor action prostate cancer metabolic disease diabetes |
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Appointments: Professor of Physiology and Pharmacology Professor of Anesthesiology |
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Brain and Spinal Cord Cancer |
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Laparoscopic and Endoscopic Surgery GI Tract - Upper (includes esophagus stomach gallbladder and biliary system) Pancreatic Cancer Laparoscopic Surgery |
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Mohs surgery melanoma |
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Appointments: Associate Professor Director, Pathology Core, OHSU Knight Cancer Institute |
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Breast Pathology Renal Pathology Transplantation Pathology |
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Appointments: Faculty member, Center for Spatial Systems Biology Research member, Knight Cancer Institute Faculty member, Neuroscience Graduate Program Leadership Team, Oregon Nanoscience and Microtechnologies- Institute (ONAMI) |
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intestinal stem cell niche metastatic cancer cell fusion colorectal cancer |
External Program Members
| Researcher | Research Area |
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| Bernard Fox, Ph.D. |
Providence |
| Arup Indra, Ph.D. | Molecular & Medical Genetics, Shriners |
| Walter Urba, M.D., Ph.D. | Providence |
| Andrew Weinberg, Ph.D. | Molecular Microbiology & Immunology, Providence |
