OHSU

Juha Rantala

no picture

Email:
Phone: 503 494-3012
Fax: 503 418-9311

Current Appointment
Research Assistant Professor

Office
Biomedical Research Building, 5th Floor
3181 SW Sam Jackson Park Rd., Portland, OR 97239

Education
Ph.D., University of Turku
Postdoctoral Fellow, Oregon Health and Science University

Research Area
OHSU Center for Spatial Systems Biomedicine

Research Interests
My research has been devoted to the development of methods for high throughput genetic screens using RNA interference gene silencing, and to the application of these methods to answer fundamental question of cell regulation.

Selected Publications
  • Pellinen T, Rantala JK, Arjonen A, Mpindi JP, Kallioniemi O, Ivaska J. A functional genetic screen reveals new regulators of β1-integrin activity. J Cell Sci. 2012 Feb 1;125(Pt 3):649-61.
  • Rantala JK, Pouwels J, Pellinen T, Veltel S, Laasola P, Mattila E, Potter CS, Duffy T, Sundberg JP, Kallioniemi O, Askari JA, Humphries MJ, Parsons M, Salmi M, Ivaska J. SHARPIN is an endogenous inhibitor of β1-integrin activation. Nat Cell Biol. 2011 Sep 25;13(11):1315-24.
  • Pellinen T, Tuomi S, Arjonen A, Wolf M, Edgren H, Meyer H, Grosse R, Kitzing T, Rantala JK, Kallioniemi O, Fässler R, Kallio M, Ivaska J. Integrin trafficking regulated by Rab21 is necessary for cytokinesis. Dev Cell. 2008 Sep;15(3):371-85.
  • Rantala JK, Mäkelä R, Aaltola AR, Laasola P, Mpindi JP, Nees M, Saviranta P, Kallioniemi O. A cell spot microarray method for production of high density siRNA transfection microarrays. BMC Genomics. 2011 Mar 28;12:162.
  • Rantala JK, Edgren H, Lehtinen L, Wolf M, Kleivi K, Vollan HK, Aaltola AR, Laasola P, Kilpinen S, Saviranta P, Iljin K, Kallioniemi O. Integrative functional genomics analysis of sustained polyploidy phenotypes in breast cancer cells identifies an oncogenic profile for GINS2. Neoplasia. 2010 Nov;12(11):877-88.