OHSU

Deniz Erten-Lyons, M.D.

Deniz Erten-Lyons, M.D.

 

Assistant Professor of Neurology

 

BIOGRAPHY

Dr. Erten-Lyons is a neurologist and researcher in the areas of brain aging and dementia. After obtaining her medical degree from Hacettepe University School of Medicine in Turkey, she completed a neurology residency, followed by a fellowship in geriatric neurology at Oregon Health & Science University.

She is currently an Assistant Professor of Neurology at Oregon Health & Science University School of Medicine, and directs the Clinical Care and Therapeutics Program of the Layton Aging and Alzheimer’s Disease Center. She treats patients with neurodegenerative dementias, and serves as site principal investigator on multicenter clinical trials for Alzheimer’s disease. Dr. Erten-Lyons is also a staff neurologist at the Portland Veterans Affairs Medical Center where she directs the Geriatric Neurology Fellowship program.

Dr. Erten-Lyons’ research interest is in understanding why some individuals age with minimal or no cognitive decline. To this end, she examines the relationship between neuropathology and cognitive decline and brain volume changes in the oldest old, as well as how life style factors, genetics, and other co-morbidities modify this relationship. Dr. Erten-Lyons has received research support from the National Institute on Aging, Alzheimer's Association, US Department of Veterans Affairs, and the Medical Research Foundation of Oregon. 

 

Publications

Erten-Lyons D, Woltjer R, Kaye JC, Mattek N, Dodge HH, Green S, Tran H, Howieson DB, Wild K, Silbert LC. Neuropathologic basis of white matter hyperintensity accumulation with advanced age. Neurology:2013;10;81(11):977-83.

Erten-Lyons D, Dodge HH, Woltjer R, et al. Neuropathologic Basis of Age-Associated Brain Atrophy. JAMA Neurol. 2013;70(5):616-22.
    
Erten-Lyons D, Sherbakov L, Piccinin AM, Hofer, SM, Dodge HH, Quinn JF, Woltjer RL, Kramer PL, Kaye JA. Review of selected databases of longitudinal aging studies.  Alzheimer’s and Dementia. 2011:;8(6):584-9.

Silbert L, Dodge HH Perkins LG, Sherbakov L,  Lahna D, Erten-Lyons D,  Woltjer R, Shinto L, Kaye JA. Trajectory of White Matter Hyperintensity Burden Preceding Mild Cognitive Impairment. Neurology; 2012 79:741-747.

Erten-Lyons D, Wilmot B, Anur P, McWeeney S, Westaway SK, Silbert L, Kramer P, Kaye J. Microcephaly genes and risk of late-onset Alzheimer disease. Alzheimer Dis Assoc Disord. 2011;25(3):276-82.

Kramer PL, Xu H, Woltjer RL, Westaway SK, Clark D, Erten-Lyons D, Kaye JA, Welsh-Bohmer KA, Troncoso JC, Markesbery WR, Petersen RC, Turner RS, Kukull WA, Bennett DA, Galasko D, Morris JC, Ott J. Alzheimer disease pathology in cognitively healthy elderly: A genome-wide study. Neurobiol Aging. 201;32(12):2113-22.

Woltjer RL, Duerson K, Fullmer JM, Mookherjee P, Ryan AM, Montine TJ, Kaye JA, Quinn JF, Silbert L, Erten-Lyons D, Leverenz JB, Bird TD, Pow DV, Tanaka K, Watson GS, Cook DG. Aberrant detergent-insoluble excitatory amino acid transporter 2 accumulates in Alzheimer disease.J Neuropathol Exp Neurol. 2010;69(7):667-76.

Erten-Lyons D, Jacobs A, Kramer P, Grupe A, Kaye J. The FAS gene, disease progression and brain volume in Alzheimer disease. Alzheimers Dement. 2010;6(2):118-24.

Erten-Lyons D, Oken B, Woltjer R, Quinn J. Relapsing polychondritis: An uncommon cause of dementia. BMJ Case Rep. Epub 2009 Feb 2.

Erten-Lyons D, Woltjer RL, Dodge H, Nixon R, Vorobik R, Calvert JF, Leahy M, Montine T, Kaye J. Factors associated with resistance to dementia despite high Alzheimer disease pathology. Neurology. 2009;72(4):354-60.

Erten-Lyons D, Oken B, Woltjer R, Quinn J. Relapsing polychondritis: An uncommon cause of dementia. J Neurol Neurosurg Psychiatry 2008;79(5):609-10.

Erten-Lyons D. When should patients with Alzheimer disease stop driving? Neurology 2008;70(14):e45-47

Erten-Lyons D, Howieson D, Moore M, Quinn J, Sexton G, Silbert L, Kaye J. Brain volume loss in MCI predicts dementia. Neurology 2006;66:233-235.

PROFESSIONAL EDUCATION

Hacettepe University, Ankara, Turkey:  MD, 1998

Kaiser Permanente Medical Center, Los Angeles, California:  Internship, 1999

Oregon Health & Science University, Portland, Oregon: Neurology Residency, 2003

Portland Veterans Affairs Medical Center, Portland, Oregon: Geriatric Neurology Fellowship, 2005

 

CONTACT

Phone:  503 494-6976

Email:  ertenlyo@ohsu.edu