The Proteomics Shared Resource is one of several OHSU resources supported by the Knight NCI Cancer Center Support Grant. The grant ensures that management and support services are available for the researchers and programs of the OHSU Knight Cancer Institute.
The OHSU Proteomics Shared Resource facility was established to make state-of-the-art mass spectrometry-based protein analytical capabilities available to the biomedical research community at OHSU.
OHSU Knight Cancer Institute members on campus receive a 30% discount on fees for services.
The facility is located in the Medical Research Building on OHSU’s Marquam Hill campus. It is fully equipped to perform protein identification, expression analysis and structural investigations using protein chemistry and mass spectrometric techniques.
Samples from off-campus organizations are also accepted. An additional 50% surcharge applies to work with for-profit organizations.
Meet our Team
- Larry David, Ph.D.
- Debra McMillen M.S.
Senior Research Associate
- John Klimek
The OHSU Proteomics Shared Resource facility is located in 700 sq. ft. of laboratory space in the Medical Research Building on Marquam Hill and is fully equipped to perform protein identification, expression analysis, and structural investigations using protein chemistry and mass spectrometric techniques. Samples from off campus organizations are also accepted, however different rates may apply. We offer several different services to labs, both at OHSU and around the world.
Here are some examples of what we can do for you:
- Protein Identification / Partial Sequencing
- Identification and Localization of Post-Translational Modifications
- Relative Quantitative Analysis via label-free analysis
- Targeted MRM analysis on known proteins
- Determination of whole protein mass
More details are available in Services & Costs. We also advise consulting with us prior to starting an experiment to increase your chances for success. This is especially important for procedures, such as identifying Post-Translational Modifications, which can otherwise have a low success rate. An overview of how we perform each of these analyses can be found in the guide to Mass Spectrometry Based Proteomics in the educational portion of our website.
Larry David Ph.D. - Director
Ashok Reddy Ph.D. - Associate Director
Debra McMillen - Senior Research Associate
John Klimek - Research Associate
Eileen Yue - Research Associate
Visit our Personnel page for more information about the PSR lab members.