Welcome

Lisa Coussens PhD

The overarching mission of the OHSU Department of Cell, Developmental & Cancer Biology is to advance the understanding of problems relevant to human health and disease. To accomplish this mission, research groups in the department have historically focused on questions regarding cell structure, organelles, life cycle, differentiation, and regulated communication between cells and extracellular signals and cues. An ultimate application of knowledge gained from these studies has been to understand important cell physiologic processes that effect human biology. These issues directly link to problems of interest to developmental biologists, including molecular and cellular mechanisms regulating tissue morphogenesis, tissue polarity and patterning. Read full welcome message here.

Featured stories and photos

ODDS 2026 presenter group photo
Speakers group photo at the 2026 Oregon Drug Discovery Symposium.

The Center for Experimental Therapeutics (CET) organized the second annual Oregon Drug Discovery Symposium on April 8-9, 2026. Governor Tina Kotek and OHSU President Dr. Elnahal gave the opening remarks of this two-day conference that was attended by over 450 people.

BCCPC Thrivership Community Conference, Nov 2025

Aaron Grossberg, Teresa Zimmers, and Liem Quang Le-Lau hosted a Brenden-Colson Center for Pancreatic Care Pancreatic Cancer Thrivership Community Conference on November 8 with speakers and presenters from the OHSU Knight Cancer Institute, including Brittany Counts and Sara Ota of CDCB, and Pancreatic Cancer Action Network's Portland Affiliate.  We hosted 45 family members, caregivers, and survivors for lectures, lunch, lab tours, and an interactive panel. It was wonderful to be in community with people facing this tough disease, particularly when Pancreatic Cancer Awareness month shines a light on the people, families, and caregivers affected.

Lisa Coussens and David Huang together at the NAM induction ceremony
In recognition of their contributions to the fields of cancer research and eye disease diagnosis and care, respectively, Lisa Coussens, Ph.D. (right), and David Huang, M.D., Ph.D. (left), were inducted this past weekend into the National Academy of Medicine as members of the class of 2024. October 18, 2025.
Missy Wong KCI Leadership

Dr. Missy Wong has been appointment as the Knight Cancer Institute's associate director of basic science. She steps into this role formerly held by Dr. Lisa Coussens who was named a co-deputy director in the KCI. After conducting a national search for this position, the search committee selected Dr. Wong from a strong slate of internal and external candidates. Missy has been at OHSU and a member of the Knight Cancer Institute for over 20 years. She currently serves as vice chair for the Department of Cell, Developmental and Cancer Biology in the OHSU School of Medicine, and has served as co-leader of the Cancer Biology Program for three competitive renewals of the KCI P30 grant from the National Cancer Institute, with three different co-leaders. Missy’s accomplishments as a scientist are well-recognized, particularly her laboratory’s research on the physiologic impact of cell fusion hybrids between circulating bone marrow-derived and intestinal tumor epithelial cells in advancing tumorigenesis.

Her history of collaborative team science and mentoring are notable, and her commitment to Community Outreach and Engagement (COE) and DEI add to our confidence in her success in this next chapter of her scientific leadership. In this new role, she will collaborate with Dr. Coussens, as well as Dr. Eneida Nemecek, associate director of clinical research, and Dr. Shelley Tworoger, associate director of population science, to guide the development of innovative policies and programs to further discovery-based science across all four research programs. 

2026 International Women's Day Symposium

International Women's Day Symposium trainee presenters
Trainee presenters at the International Women's Day Symposium.
Top row: Dr. Katie Blise, Dr. Brittany Counts, Dr. Jennifer Eng.
Bottom row: Margaret Haerr, Katherina Pelz, Dr. Divya Ravi.

The Lustgarten Foundation partnered with the OHSU Knight Cancer Institute to hold its annual International Women's Day Symposium on March 10th, 2026 at OHSU's Knight Cancer Research Building. Co-chaired by Lisa M. Coussens, PhD and Lustgarten's Chief Medical Advisor Elizabeth Jaffee, MD, The Power of Persistence–Women Transforming Cancer Research and Care brought together incredible women leaders who are driving progress, breaking barriers, and shaping the future of pancreatic cancer research and patient care. View the full program.

From groundbreaking science to powerful personal journeys, their stories remind us that persistence fuels progress—and change is possible because of it.

Watch the full symposium recording and be inspired by the voices leading the way.

International Women's Day Symposium_Presenters group photo
Presenters at the 2026 International Women's Day Symposium.

CDCB News

Recent accolades and funding

Congratulations to Dr. Jonathan Brody who has received the notice of award for his R01 titled "Leveraging Hyperglycemia for the treatment of pancreatic cancer."

Dr. Teresa Zimmers has been invited to organize a plenary session at AACR's 2027 Annual Meeting titled "Novel Strategies in the Dual Treatment of cancer and cachexia." Congratulations!

Drs. Teresa Zimmers and Aaron Grossberg organized the Pancreatic Cancer Thriveship Community Conference on October 24. The Thriveship conference was a half-day gathering designed for patients, families, and caregivers to connect directly with doctors, researchers, and care providers in interactive sessions that offered practical guidance, mutual support, and real dialogue. Read more on OHSU Now.

Congratulations to Rohan Chaudhari, MD/PhD student in the Burger lab, who received a Frohnmayer Hicks Sciaretta Cancer Research Scholars Award and a Tartar Trust Fellowship!

The Wong lab has several announcements to share:

The Moreau lab would like recognize Maryam Al-Ghezi's recent accolades:

  • Maryam received a travel award to attend the Montagna Symposium on the Biology of Skin in October 2026, where she presented a flash talk and won the 1st place poster prize.
  • Maryam also received a Frohnmayer Hicks Sciarretta Cancer Research Scholar Award.

Recent publications

The Enns lab has published "The neogenin-hemojuvelin axis in murine liver is crucial for hepcidin expression" in the American Journal of Physiology-Gastrointestinal and Liver Physiology.

Dr. Breanna Maniaci, one of our recent PhD graduates from the Maxson lab, has published as first-author "CSF3R compound mutations produce a hyperproliferative leukemia driven by overexpression of PIM kinases" in Blood.

Dr. Robert Eil and collaborator Dr. Rahul Roychoudhuri, University of Cambridge, published "Tumor-derived antioxidants suppress immunity by depriving T cells of reactive oxygen species" in Science. Drs. Eil and Roychoudhuri shared senior authorship on the publication, which identifies a new mechanism of tumor immune suppression.

Amanda Zucker, MD/PhD student in Wong lab, has had her paper accepted for publication in the Journal of Biomedical Optics.

Madison Hall, graduate student in the Braun lab, is first-author on the recent manuscript "Mutant ASXL1 Drives Transcriptional Activation and Repression in Human Hematopoiesis" 

Drs. Jonathan Brody, Kate Byrne, Aaron Grossberg, Teresa Zimmers, and Rosie Sears and members of their labs have published "Schedule-dependent efficacy of gemcitabine and RAS(ON) inhibition in orthotopic pancreatic cancer: implications for clinical trial design" in Cancer Letters. Intending for it to lead to a clinical trial that they are setting up here at OHSU.

The Byrne lab has co-published a paper with the Xia lab, along with Dr. Lisa Coussens and several other collaborators at OHSU, titled "IFN-γ-dependent tumor-cell MHC-II is restrained by MAPK signaling and associated with immunotherapy responsiveness in pancreatic ductal adenocarcinoma” in Cancer Immunology Research. 

Dr. Miffy Guo, one of our PhD graduates who successfully defended earlier this year, led a collaborative study with Drs. Robert Eil and Jonathan Brody, among other colleagues at OHSU leading to her first-author publication "The Posttranscriptional Regulator HuR Promotes Immune Evasion in Pancreatic Ductal Adenocarcinoma" in Cancer Immunology Research.

Knight Cancer Institute Trainee Travel Grants

Travel awards are available for graduate students and postdoctoral fellows conducting cancer-focused research with Knight-affiliated faculty. Up to $1500 in funding will be awarded to selected trainees who will present their research at a national meeting but may not have sufficient funds available.

Graduate student travel awards are supported by a generous gift from the Frohnmayer Hicks Sciarretta Cancer Research Scholars Program. Postdoctoral travel awards are supported by the Knight Cancer Research Training and Education Coordination Office. 

The 2026 deadline for applications are:

  • January 15, 2027
  • April 15, 2027
  • July 15, 2027
  • October 15, 2027

For more information, visit the Knight Cancer Institute Trainee Travel Grants SharePoint Site or email us at KnightEDU@ohsu.edu

CDCB labs recruiting

Careers with an emphasis on preclinical and translational science

Faculty news

Julia Maxson, Ph.D.

Congratulations to Dr. Julia Maxson on being granted tenure!

Amy Moran, Ph.D.

Congratulations to Dr. Amy Moran on her promotion to Full Professor with indefinite tenure of Cell, Developmental & Cancer Biology!

Josh Walker

Congratulations to Dr. Josh Walker on his promotion to Associate Professor of Radiation Medicine!

Evan Lind, Ph.D.

Congratulations to Dr. Evan Lind on his promotion to Full Professor of Molecular Microbiology and Immunology!

Jonathan Brody

Congratulations to Dr. Jonathan Brody on being granted indefinite tenure!