Paper of the Month

The School of Medicine spotlights a recently published faculty research paper each month. The goals are to highlight the great research happening at OHSU and to share this information across departments, institutes and disciplines.

February 2017

Mitalipov LabFrom bad egg to good egg

February's featured paper is titled, "Functional human oocytes generated by transfer of polar body genomes," published in Cell Stem Cell. It was an extensive effort from researchers at OHSU's Center for Embryonic Cell and Gene Therapy, led by Shoukhrat Mitalipov, Ph.D., center director and professor of biomedical engineering, obstetrics and gynecology, pediatrics, and molecular and medical genetics, OHSU School of Medicine, in collaboration with researchers at the Salk Institute for Biological Studies in La Jolla, Calif., led by Joseph R. Ecker, Ph.D. Its co-first authors are Hong Ma, M.D., Ph.D., staff scientist, OHSU, and Ryan C. O'Neil, graduate student, Salk Institute.

Overcoming infertility

The birth of Louise Brown in 1978 represented a landmark achievement in reproductive medicine. She was the first child born from in vitro fertilization (IVF), the process of fertilizing an egg (also called an oocyte) outside the body and transplanting it back into the uterus. Since that time, IVF has become a commonplace practice, with over five million children born using IVF or other reproductive measures. Read more


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