Research Projects

The OHSU School of Dentistry encourages and supports research concerning dental disease, clinical techniques, oral biology, and basic biomedical research. The basic science and clinical research faculty have their primary appointments, teaching commitments and laboratories at the school of Dentistry. Research projects are funded by Federal grants (NIH, NSF, NASA) as well as a variety of corporate sponsors. More than twenty principal investigators and numerous technical staff pursue a wide variety of project listed below, ranging in scope from the basic mechanisms of diseases to evidenced-based dental treatment. For further information and opportunities for research contact the principal investigators or the Office of Research Affairs at the School of Dentistry.

Recent Publications:

Assael LA. Readiness and response: the oral and maxillofacial surgeon's role in disaster. J Oral Maxillofac Surg. 2005;63(11):1565-6.

Balkowiec A, Katz DM. Cellular mechanisms regulating activity-dependent release of native brain-derived neurotrophic factor from hippocampal neurons. J Neurosci. 2002;22(23):10399-407.

Siqueira JF Jr, Rocas IN, Baumgartner JC, Xia T Searching for Archaea in Infections of Endodontic Origin. J Endod. 2005;31(10):719-722.

Danilchik MV, Bedrick SD, Brown EE, Ray K. Furrow microtubules and localized exocytosis in cleaving Xenopus laevis embryos. J Cell Sci. 2003;116(Pt 2):273-83.

Wilmarth PA, Riviere MA, Rustvold DL, Lauten JD, Madden TE, David LL. Two-dimensional liquid chromatography study of the human whole saliva proteome.

J Proteome Res. 2004;3(5):1017-23.

Ferracane JL. Hygroscopic and hydrolytic effects in dental polymer networks. Dent Mater. 2005 Aug 5.

Hilton T, Hilton D, Randall R, Ferracane JL. A clinical comparison of two cements for levels of post-operative sensitivity in a practice-based setting. Oper Dent. 2004;29(3):241-8.

Knittel LM, Kent KS. Remodeling of an identified motoneuron during metamorphosis: hormonal influences on the growth of dendrites and axon terminals. J Neurobiol. 2005;63(2):106-25.

King SC. The "Transport Specificity Ratio": a structure-function tool to search the protein fold for loci that control transition state stability in membrane transport catalysis. BMC Biochem. 2004;5:16.

Harms MJ, Wilmarth PA, Kapfer DM, Steel EA, David LL, Bachinger HP, Lampi KJ. Laser light-scattering evidence for an altered association of beta B1-crystallin deamidated in the connecting peptide. Protein Sci. 2004 Mar;13(3):678-86.

Laughlin GA, Eick JD, Glaros AG, Young L, Moore DJ. A comparison of palatal adaptation in acrylic resin denture bases using conventional and anchored polymerization techniques. J Prosthodont. 2001;10(4):204-11.

Li B, Li X, Bai Y, Hou JJ, Ma M, Machida CA. Simian retrovirus serogroup 2 constitutive transport element recognizes the ribosomal L10-like protein and translocon gamma subunit-like protein in a yeast three-hybrid assay. Virus Res. 2004;99(1):69-80.

Boyd LD, Madden TE. Nutrition, infection, and periodontal disease. Dent Clin North Am. 2003 Apr;47(2):337-54. Review.

Bakin AV, Stourman NV, Sekhar KR, Rinehart C, Yan X, Meredith MJ, Arteaga CL, Freeman ML. Smad3-ATF3 signaling mediates TGF-beta suppression of genes encoding Phase II detoxifying proteins. Free Radic Biol Med. 2005;38(3):375-87.

Wuenschmann, A., Marshall, B., Mitchell, J.C., and Weisbrode, S. Calcium Hydroxylapatite Deposition Disease in a Great Dane Puppy. Veterinary Pathology 2000;37:346-349.

Morton DB. Invertebrates yield a plethora of atypical guanylyl cyclases. Mol Neurobiol. 2004;29(2):97-116. Review.

Robertson LT, Levy JH, Petrisor D, Lilly DJ, Dong WK. Vibration perception thresholds of human maxillary and mandibular central incisors. Arch Oral Biol. 2003;48(4):309-16.

Rosenstein DI. Oral health and HIV. BETA. 2004,16(2):26-31.

Sakaguchi RL, Wiltbank BD, Murchison CF. Cure induced stresses and damage in particulate reinforced polymer matrix composites: a review of the scientific literature. Dent Mater. 2005;21(1):43-6. Review.

Shih M, Ma H, Nakajima E, David LL, Azuma M, Shearer TR. Biochemical properties of lens-specific calpain Lp85. Exp Eye Res. 2005 Jul 26; [Epub ahead of print]