Pulmonary and Critical Care & Sleep Medicine

The Pulmonary and Critical Care & Sleep Medicine (PRISM) research team is based in the Division of Pulmonary and Critical Care Medicine. PRISM was established in 2008 by Akram Khan, MD (MBBS) as the principal investigator to advance research to improve patient outcomes in Acute Respiratory Distress Syndrome, and Sepsis. Our group also has trials on Pulmonary Artery Hypertension, Chronic Obstructive Pulmonary Disease, Pulmonary Fibrosis and Asthma in outpatient settings. 

We are part of the Clinical Trials Network for the Prevention and Early Treatment of Acute Lung Injury (PETAL). PETAL is a network of 12 Clinical Centers (CC) and one Clinical Coordinating Center (CCC) funded by the National Heart, Lung, and Blood Institute (NHLBI) to develop and conduct randomized controlled clinical trials to prevent or treat Acute Respiratory Distress Syndrome (ARDS) and Sepsis which is the leading cause of ARDS. We are also working with VICTAS to study Vitamin C, Thiamine and steroids and sepsis.

We provide opportunities to residents and fellows to be involved in clinical research, learn about clinical trial design, and help enroll patients in ongoing studies which helps them developed understanding of the clinical trials process and design their own research. Residents and fellows have collaborated with us and found the time spent with PRISM very satisfying and educational. They have submitted abstracts to national meetings and publish papers.

We also provide opportunities to college student volunteers interested in careers in healthcare for data abstraction and supporting research coordinators. This allows exposure to research methods and clinical medicine in outpatient and intensive care unit settings. 

OHSU Hospital