The KDL was formed in January 2011 by combining four individual laboratories: the Molecular Diagnostic Center, Clinical Cytogenetics, Biochemical Genetics and the Pathology Translational Research Lab. This single laboratory entity, with a focus on cutting-edge personalized diagnostics, leverages the decades of clinical laboratory and research experience within the individual labs with the sum being much more than the parts.
Research Service Laboratories
Research Cytogenetics Laboratory
The Research Cytogenetics Lab is a fee-for-service cytogentics laboratory available to genetics researchers to assist in development and execution of cytogenetics experiments for research purposes.
OHSU Gene Microarray Shared Resource
The OHSU Gene Microarray Shared Resource (GMSR) functions as a full-service genomics facility serving research scientists and clinicians with DNA microarray services for RNA expression profiling and DNA variation analysis on two microarray platforms, Affymetrix and Illumina.
The Laboratory of Dr. Paul Spellman is interested in using genetic, genomic, and proteomic data to understand and model the biology of cancer and to develop methods to effectively deploy therapeutic agents in the age of molecularly guided medicine.
The Laboratory of Dr. H. Scott Stadler is focused on discerning the molecular functions of vertebrate Hox proteins in normal development and disease. The Hox proteins are an evolutionarily conserved group of helix turn helix transcription factors that exhibit remarkable conservation in sites of expression, chromosomal clustering, and loss of function phenotypes in both vertebrate and invertebrate species.