OHSU

Peter Zuber

Peter Zuber

Email: 
Phone:  503 748-7335
Fax:  503 748-1464
Lab Phone: 503 748-1056

 

Current Appointments

Professor, Division of Environmental and Biomolecular Systems
Affiliate Scientist, Center for Coastal Margin Observation and Prediction

 

Education

B. S., Microbiology, University of Maine, Orono, 1976
Ph.D. Microbiology, University of Virginia School of Medicine, Charlottesville, 1982

 

Biography

  • Harvard University, Cellular and Developmental Biology, Laboratory of Richard Losick, American Cancer Society Postdoctoral Fellow, 1982-85; Research Associate, 1985-86
  • Oklahoma State University, Assistant Professor, Department of Botany and Microbiology, 1986-88
  • Louisiana State University Medical Center at Shreveport, Department of Biochemistry and Molecular Biology, Assistant Professor, 1988-92, Associate Professor, 1992-96, Professor, 1996-98
  • Harvard Medical School, Visiting Professor, Biological Chemistry and Molecular Pharmacology, Laboratory of Christopher T. Walsh, 1996
  • Editorial Board: Journal of Bacteriology
  • Editorial Board: Applied and Environmental Microbiology
  • Advisory Board: Molecular Microbiology
  • Associate Editor: Microbiology

 

Research Interests

Regulation of prokaryotic gene expression and development in response to stress; signal transduction; regulation and mechanism of peptide antibiotic biosynthesis; regulation of genetic competence in Bacillus subtilis.

 

Selected Publications

Lin, A. A.; Zuber, P. (2012) Evidence that a single monomer of Spx can productively interact with RNA polymerase in Bacillus subtilis. J. Bacteriol., 194, 1697-1707. (DOI: 10.1128/jb.06660-11)

Herfort, L.; Peterson, T. D.; Prahl, F. G.; McCue, L. A.; Needoba, J. A.; Crump, B. C.; Roegner, G. C.; Campbell, V.; Zuber, P. (2012) Red waters of Myrionecta rubra are biogeochemical hotspots for the Columbia River estuary with impacts on primary/secondary productions and nutrient cycles. Estuaries Coasts, 35, 878-891. (DOI: 10.1007/s12237-012-9485-z)

Fortunato, C. S.; Herfort, L.; Zuber, P.; Baptista, A. M.; Crump, B. C. (2012) Spatial variability overwhelms seasonal patterns in bacterioplankton communities across a river to ocean gradient. ISME J., 6, 554-563. (DOI: 10.1038/ismej.2011.135)

DeLorenzo, S.; Brauer, S. L.; Edgmont, C. A.; Herfort, L.; Tebo, B. M.; Zuber, P. (2012) Ubiquitous dissolved inorganic carbon assimilation by marine bacteria in the Pacific Northwest coastal ocean as determined by stable isotope probing. PLoS One, 7, e46695. (DOI: 10.1371/journal.pone.0046695)

Chan, C. M.; Garg, S.; Lin, A. A.; Zuber, P. (2012) Geobacillus thermodenitrificans YjbH recognizes the C-terminal end of Bacillus subtilis Spx to accelerate Spx proteolysis by ClpXP. Microbiology (Reading, U. K.), 158, 1268-1278. (DOI: 10.1099/mic.0.057661-0)

Zuber, P.; Chauhan, S.; Pilaka, P.; Nakano, M. M.; Gurumoorthy, S.; Lin, A. A.; Barendt, S. M.; Chi, B. K.; Antelmann, H.; Maeder, U. (2011) Phenotype enhancement screen of a regulatory spx mutant unveils a role for the ytpQ gene in the control of iron homeostasis. PLoS One, 6, e25066. (DOI: 10.1371/journal.pone.0025066)

Kommineni, S.; Garg, S. K.; Chan, C. M.; Zuber, P. (2011) YjbH-enhanced proteolysis of Spx by ClpXP in Bacillus subtilis is inhibited by the small protein YirB (YuzO). J. Bacteriol., 193, 2133-2140. (DOI: 10.1128/jb.01350-10)

Brauer, S. L.; Adams, C.; Kranzler, K.; Murphy, D.; Xu, M.; Zuber, P.; Simon, H. M.; Baptista, A. M.; Tebo, B. M. (2011) Culturable Rhodobacter and Shewanella species are abundant in estuarine turbidity maxima of the Columbia River. Environ Microbiol, 13, 589-603.

Smith, M. W.; Herfort, L.; Tyrol, K.; Suciu, D.; Campbell, V.; Crump, B. C.; Peterson, T. D.; Zuber, P.; Baptista, A. M.; Simon, H. M. (2010) Seasonal changes in bacterial and archaeal gene expression patterns across salinity gradients in the Columbia River coastal margin. PLoS One, 5, No pp. given. (DOI: 10.1371/journal.pone.0013312)

Nakano, M. M.; Lin, A.; Zuber, C. S.; Newberry, K. J.; Brennan, R. G.; Zuber, P. (2010) Promoter recognition by a complex of Spx and the C-terminal domain of the RNA polymerase α subunit. PLoS One, 5, No pp. given. (DOI: 10.1371/journal.pone.0008664)

Zuber, P. (2009) Management of oxidative stress in Bacillus. Annu. Rev. Microbiol., 63, 575-597. (DOI: 10.1146/annurev.micro.091208.073241)

Garg, S. K.; Kommineni, S.; Henslee, L.; Zhang, Y.; Zuber, P. (2009) The YjbH protein of Bacillus subtilis enhances ClpXP-catalyzed proteolysis of Spx. J. Bacteriol., 191, 1268-1277. (DOI: 10.1128/jb.01289-08)