OHSU

Damien Fair, PhD

Damien FairPosition 

Assistant Professor, Behavioral Neuroscience
Assistant Professor, Psychiatry
Assistant Scientist, Advanced Imaging Research Center   

Contact 

faird@ohsu.edu; Phone: 503 418-0995 Office: MNP 1500 Mail Code: UHN80R1 

Research Interests 

Cognitive Brain Development; ADHD; Autism; Neuroimaging 

Preceptor Rotation Availability 

Dr. Fair might be available for rotations for upcoming academic terms.  Please contact him directly to inquire. 

Mentorship Availability 

Dr. Fair might be available for mentorship.  Please contact him directly to inquire.   

Summary of Current Research  

My laboratory focuses on mechanisms and principles that underlie the developing brain. The majority of this work uses functional MRI and resting state functional connectivity MRI to assess typical and atypical populations. A second focus has become testing the feasibility of using various functional and structural MRI techniques in translational studies of developmental neuropsyciatric disorders (e.g., attention deficit hyperactivity disorder, and autism). We are exploring ways to better characterize individual patients with these psychopathologies to help guide future diagnostic, therapeutic and genetic studies. 

Selected recent publications

Fair, D.A., Bathula, D., Nikolas, M., and Nigg, J.T. (2012) Distinct neuropsychological subgroups in typically developing youth inform heterogeneity in ADHD. Proc Nat Acad Sci.

Mills, K.L., Bathula, D., Costa Dias, T.G., Iyer, S.P., Fenesy, M.C., Musser, E.D., Stevens, C.A., Thurlow, B.L., Carpenter, S.D., Nagel, B.J., Nigg, J.T., Fair, D.A. (2012) Altered cortico-striatal-thalamic connectivity in relation to spatial working memory capacity in children with ADHD. Frontier in Psychiatry. 

Stevens, A.A., Tappon, S.C., Garg, A., Fair, D.A. (2012) Functional brain network modularity captures inter- and intra-individual variation in working memory capacity. PLoS One.

Shannon, B.J., Raichle, M.E., Snyder, A.Z., Fair, D.A., Mills, K.L., Zhang, D., Bache, K., Calhoun, V.D., Nigg, J.T., Nagel, B.J., Stevens A.A., Kiehl, K.A. (2011) Premotor functional connectivity predicts impulsivity in juvenile offenders. Proc Nat Acad Sci. 108(27):11241-5.

Power, J.L., Fair, D.A., Schlaggar, B.L., Petersen, S.E. (2010). The Development of Human Functional Brain Networks. Neuron. 67(5):735-48.

Dosenbach, N.U.F., Nardos, B., Cohen, A.L., Fair, D.A., Power, J.D., Church, J.A., Nelson, S.M., Wig, G.S., Vogel, A.C., Lessov-Schlaggar, C.N., Barnes, K.A., Dubis, J.W., Feczko, E. , Coalson, R.S., Pruett, J.R., Barch, D.M., Petersen, S.E., Schlaggar, B.L. (2010) Prediction of individual brain maturity using fMRI. Science. 329(5997):1358-61.

Herting, M.M., Fair, D.A., Nagel, B.J. (2010). Altered fronto-cerebellar connectivity in alcohol-naive youth with a family history of alcoholism. Neuroimage. Epub ahead of print

Fair, D.A., Posner, J., Nagel, B.J., Bathula, D., Costa Dias, T.G., Mills, K.L., Blythe, M.S., Giwa, A., Schmitt, C.F., Nigg, J.T. (2010). Atypical Default Network Connectivity in Youth with ADHD. Biol Psychiatry. Epub ahead of print 

Fair, D.A., Bathula, D., Mills, K.L., Costa Dias, T.G., Blythe, M.S., Zhang ,D., Snyder, A.Z., Raichle, M.E., Stevens, A.A., Nigg, J.T., Nagel, B.J. (2010) Maturing thalamocortical functional connectivity across development. Frontiers in Systems Neuroscience. 18;4:10.

Fair, D.A., Choi, A.H., Dosenbach, Y.B.L., Coalson, R.S., Miezin, F.M., Petersen, S.E., Schlaggar, B.L. (2009) The functional organization of trial-related activity in lexical processing after early left hemispheric brain lesions: An event-related fMRI study. Brain and Language. Epub ahead of print.

Fair, D.A., Cohen, A.L., Powers, J.L., Dosenbach, N.U.F., Church, J.A., Miezin, F.M., Schlaggar, B.L., Petersen, S.E. (2009). Functional Brain Networks Develop from a "Local to Distributed" Organization. PLoS Comp Bio. 5(5): e10000381

Fair, D.A., Cohen, A.L., Dosenbach, N.U.F., Church, J.A., Miezin, F.M., Barch, D.M., Raichle, M.E., Petersen, S.E., Schlaggar, B.L. (2008). The maturing architecture of the brain's default network. Proc Nat Acad Sci. 105(10): 4028-32.

Church, J.A., Fair, D.A., Dosenbach, N.U.F., Cohen, A.L. Miezin, F.M., Petersen, S.E., Schlaggar, B.L. (2008) Task control networks in adolescents with Tourette Syndrome show immature and atypical patterns of functional connectivity. Brain. 132(1):225-38

Fair, D.A., Snyder, A.Z., Connor, L., Nardos, B., Corbetta, M. (2008) A comparison of the BOLD response in areas with and without diaschisis. Neurorehabilitation and Neural Repair. 23(1):52-7

Cohen, A.L., Fair, D.A., Dosenbach, N.U.F., Miezin, F.M., Dierker, D., Van Essen, D.C., Schlaggar, B.L., Petersen, S.E. (2008). Defining functional areas in individual human brains using resting functional connectivity MRI. Neuroimage. 41(1):45-57

Dosenbach, N.U.F., Fair, D.A., Cohen, A.L., Schlaggar, B.L., Petersen, S.E. (2008). A dual networks architecture of top down control. Review. Trends in Cognitive Neuroscience. 12(3): 99-105.

Becker, D.B., Schlaggar, B.L., Sachananandi, N., Coalson, R.S., Lugar, H.M., Fair, D.A., Kirchner, L.E., Kanel, A.A. (2008) Functional neuroanatomy of lexical processing in children with cleft lip and palate. Plastic and Reconstructive Surgery. 122(5):1371-82

Fair, D.A., Dosenbach, N.U.F., Church, J.A., Cohen, A.L., Miezin, F.M., Barch, D., Petersen, S.E., Schlaggar, B.L. (2007) Development of distinct task control networks through segregation and integration. Proc Nat Acad Sci. 104(33):13507-13512.

Fair, D.A., Schlaggar, B.L., Cohen, A.L., Miezin, F.M., Dosenbach, N.U.F., Wenger, K.K., Fox, M.D., Snyder, A.Z., Raichle, M.E., Petersen, S.E. (2007) A method for using blocked and event-related fMRI data to study "Resting State" functional connectivity. Neuroimage. 35(1):396-405.

Dosenbach, N.U.F., Fair, D.A., Miezin, F.M., Cohen, A.L., Wenger, K.K., Dosenbach, R.A., Fox, M.D., Snyder, A.Z., Vincent, J.L., Raichle, M.E., Schlaggar, B.L., Petersen, S.E.  (2007) Distinct brain networks for adaptive and stable task control in humans. Proc Nat Acad Sci. 104(26):11073-11078.

Fair, D.A., Brown, T., Petersen, S. & Schlaggar, B. (2006) fMRI reveals novel functional neuroanatomy in a child with perinatal stroke. Neurology, 67(12):2246-2249. 

Education

2003-2008   Ph.D., Neuroscience, Washington University School of Medicine St. Louis, MO (Advisors: Bradley Schlaggar, Steven Petersen)   

1999-2001   MMSc, Physician Associate Program, Yale University School of Medicine, New Haven, CT (Advisor: Lawrence Brass) 

1994-1998   B.A., Biology (Maj) and Chemistry (Min), Augustana College, Sioux Falls, SD                                                       

Previous Positions

2008-2011   Postdoctoral Research Scientist, Psychiatry Dept, Oregon Health and Science University (Advisors: Joel Nigg, Bonnie Nagel)   

2001-2003   Physician Assistant, Clinical Instructor, Yale University School of Medicine/Yale New Haven Hospital, Dept. of Neurology