Larry David, the core's director, is a protein chemist with over 10 years of experience studying proteins using mass spectrometry. His research interests include studying age-related modifications in proteins by mass spectrometry, and in addition to directing the core is a principal investigator conducting NIH sponsored research.
Ashok Reddy, the core's associate director, is a bioanalytical chemist who assists the director of the OHSU Proteomics Shared Resource in managing proteomics projects across the entire university. He has 14 years of experience conducting cancer research including the world's largest cancer dose response study and 9 years of experience conducting proteomics/biomarker discovery studies in human body fluids, such as serum, saliva, cervico-vaginal fluid (cvf), amniotic fluid and urine. He has managed large cancer and proteomics projects from conception to discovery as demonstrated by the successful discovery of biomarkers of infection for Pre-term birth, Preeclampsia, and Neonatal sepsis. His work with protein biomarkers led to venture capital investment of $20 million for his former employer Proteogenix, Inc. His research interests are in disease biomarkers in body fluids and tumor markers in cancer tissues.
Deb joined the PSR in January 2004 coming to OHSU from the Genomics and Proteomics laboratory at the University of Oregon in Eugene. Although the PSR lab is focused solely on mass spectrometric analysis of proteins, Deb brings to the lab her experience in N-terminal protein sequence analysis, peptide synthesis, amino acid composition analysis of proteins, HPLC and use of the Biacore X for binding studies. Her research interest includes improving methodologies for MRM analysis on the QTRAP4000. For fun she enjoys travel, especially to Italy, and sea kayaking on Oregon's lakes and gentle rivers.
John came to PSR in 2006. He previously worked for the Proteomics Core Facility at the Institute for Systems Biology in Seattle Washington. His past research includes studies into the effects of particular mutations on the fuctioning of genes in drosophila. In Seattle John spent most of his time providing proteomics services for clients but also created MS/MS databases from a multitude of different instuments to aid in the development of peptide and protein identification software. Here at PSR John spends his time as handling many of the smaller projects; operating instruments, performing data analysis, and processing billings. John spends much of his free time at home with his wife and two young daughters.
Eileen (GuiHua) Yue
Eileen is an analytical chemist with extensive experience in the field of proteomics who is currently working part time for PSR. Her past research included using monolith column and mass spectrometry for the determination of trace sample such as LCM sample, microfluidic chip linked to mass spectrometry and other advanced proteomics technology. Currently, she applies proteomics to answer biology questions. Eileen enjoys running, listening music and raising her kids.