2004-2005 Series
SEPTEMBER 2004
September 13, 2004
K Channel Biology: From Structure to Disease
Colin G. Nichols, Ph.D.
Department of Cell Biology and Physiology, Washington University School of Medicine
Host: Ed McCleskey
September 30, 2004
Signaling through protein phosphorylation
Tony Hunter, Ph.D.
The Salk Institute, San Diego, CA
Host: John Scott
OCTOBER 2004
October 7, 2004
Autoregulation of synaptic strength in central neurons
Richard Tsien, Ph.D.
Department of Molecular and Cellular Physiology, Stanford
Host: John Adelman
October 14, 2004
Nuclear receptor control of lipid metabolism
David Mangelsdorf, Ph.D.
Professor, Department of Pharmacology,
UT Southwestern Medical Center, Dallas, HHMI Investigator
Host: Dick Goodman
NOVEMBER 2004
November 4, 2004
Imaging circuit assembly in the retina
Rachel Wong, Ph.D.
Washington University at Saint Louis
Host: Larry Trussell
November 11, 2004
Stop and go during development: Directing vesicular traffic during synapse formation
A. Kimberly McAllister, Ph.D.
Center for Neuroscience, University of California, Davis
Host: Gary Westbrook
November 18, 2004
Signaling to extrasynaptic receptors in cerebellum
Thomas Otis, Ph.D.
Department of Neurobiology, UCLA Medical School
Host: Craig Jahr
DECEMBER 2004
December 2, 2004
Transcriptional activators, co-factor complexes and disease
Robert Tjian, Ph.D.
Howard Hughes Medical Institute, Molecular & Cell Biology, University of California, Berkeley
Host: Dick Goodman
December 6, 2004
Quantification of transporter protein densities and modelling of transmitter diffusion in a CNS synapse
Knut Petter Lehre, Ph.D.
Department of Anatomy, University of Oslo, Norway
Host: Henrique von Gersdorff
December 9, 2004
Mechanisms Regulating Synaptic Dynamics in Layers 2/3 in the Visual Cortex
Lonnie Wollmuth, Ph.D.
Department of Neurology & Behavior, SUNY, Stony Brook, New York
Host: Henrique von Gersdorff
FEBRUARY 2005
February 3, 2005
The Dystrophin Complex: a Membrane Scaffold for Signaling Proteins in Muscle and Brain
Stan Froehner, Ph.D.
Department of Physiology and Biophysics, University of Washington, Seattle
Host: Gary Westbrook
February 10, 2005
Seeing Circuits Assemble
Stephen Smith, Ph.D.
Professor, Molecular & Cellular Physiology, Stanford University
Host: Wolfhard Almers
February 17, 2005
Activity-dependent homeostatic specification of neurotransmitter choice
Nicholas Spitzer, Ph.D.
Biological Sciences, University of California at San Diego
Host: Tom Soderling
February 22, 2005
PRIALT® (ziconotide intrathecal infusion): A newly approved calcium channel blocker to treat severe, chronic pain
George Miljanich, Ph.D.
Research Fellow, Medical Affairs, Elan Pharmaceuticals, San Diego
Host: Ed McCleskey
February 24, 2005
The hyperpolarization-activated pacemaker channel: A gate of learning and memory
Steven Siegelbaum, Ph.D.
HHMI, Department of Pharmacology, Columbia University, New York, NY
Host: John Adelman
MARCH 2005
March 3, 2005
Protein synthesis at the synapse
Erin Schuman, Ph.D.
California Institute of Technology
Host: Phil Stork
March 10, 2005
Protein interactions
Stan Fields, Ph.D.
Genome Sciences, University of Washington
Host: Mike Forte
March 17, 2005
Shining a light on dendritic integration and synaptic plasticity in the hippocampus with glutamate photolysis
Scott Thompson, Ph.D.
Department of Physiology, University of Maryland, Baltimore, MD
Host: John Adelman
March 31, 2005
The molecular machinery for cAMP-dependent immunomodulation in T cells
Kjetil Taskén, M.D., Ph.D.
Professor, Centre Director, The Biotechnology Centre of Oslo, Norway
Host: John Scott
APRIL 2005
April 7, 2005
Comparative Kinomics: How Genome Sequences and a Billion Years of Evolution can Help Us Understand Protein Kinases and Cell Signaling
Gerard Manning, Ph.D.Bioinformatics, Salk Institute for Biological Sciences, San Diego, CA
Host: John Scott
April 8, 2005
Cross-talk between the mechano-gated K2P channel TREK-1 and the actin cytoskeleton
Eric Honoré, Ph.D.
Institut de Pharmacologie Moléculaire et Cellulaire, Centre National de la Recherche Scientifique, Université de Nice, Sophia-Antipolis, France
Host: John Adelman
April 14, 2005
NHR-49: A C. elegans nuclear hormone receptor that affects lifespan and modulates fat storage, consumption and composition
Keith Yamamoto, Ph.D.
Executive Vice Dean, School of Medicine, UC San Francisco, CA
Host: Dick Goodman
April 21, 2005
Regulating early signaling by antigen receptors
Arthur Weiss, M.D., Ph.D.
HHMI, Department of Microbiology and Immunology, University of California, San Francisco
Host: Phil Stork
April 28, 2005
Phosphoserine/Threonine-Binding Domains: Integrators of Protein Kinase Signaling in Cell Cycle Control and Cancer
Michael Yaffe, M.D., Ph.D.
Associate Professor, Department of Biology, Center for Cancer Research, Massachusetts Institute of Technology
Host: John Scott
MAY 2005
May 9, 2005
Molecular Control of the Cellular Response to Oxidative Stress
Yuxin Yin, M.D., Ph.D.
Department of Radiation Oncology, College of Physicians and Surgeons, Columbia University
May 12, 2005
The Computational Algorithm of Cerebellar Purkinje Cells
Kamran Khodakhah, Ph.D.
Department of Neuroscience, Albert Einstein College of Medicine, Bronx, NY
Host: John Williams
May 26, 2005
Regulation of receptor signaling and trafficking by phosphoinositide lipids and ubiquitin
Scott Emr, Ph.D.
HHMI, Cellular and Molecular Medicine, UCSD School of Medicine
Host: Gary Thomas
JUNE 2005
June 2, 2005
Herbert Memorial Lecture: Oxygen Sensation: Unconventional Signaling for an Unconventional Sense
Cori Bargmann, Ph.D.HHMI, The Rockefeller University, New York, NY
Host: Dick Goodman
June 3, 2005
Integration of small G protein function
Phil Stork, M.D.
Host: The Vollum Institute
June 16, 2005
MicroRNAs, transcription factors and neuronal development in C. elegans
Oliver Hobert, Ph.D.
HHMI, Department of Biochemistry and Molecular Biophysics, Columbia University, NY
Host: Dick Goodman
June 22, 2005
Gene and Cell Therapy for Parkinson's and Huntington's Disease
Jeffrey H. Kordower, Ph.D.
Director, Research Center for Brain Repair, Division of Neuroscience, Rush University Medical Center, Chicago, IL
Host: Gary Westbrook
JULY 2005
July 8, 2005
Paved with Good Intentions: The Role of Cell Cycle Events in Neurodegenerative Disease
Karl Herrup, Ph.D.
Director, Alzheimer Research Center, Case Western Reserve University
Hosts: Vollum Institute and the OHSU Department of Neurology
July 28, 2005
Dissecting Synaptic Learning Rules in the Hippocampus
Gayle M. Wittenberg, Ph.D.
Department of Molecular Biology, Princeton University
Host: John Adelman
