Shoukhrat Mitalipov Lab
Human Stem Cell Discovery Named Top 10 Breakthrough - 2013!
Our paper on making human embryonic stem cells from skin cells using a procedure called somatic cell nuclear transfer recognized as Top 10 discovery for 2013 by these international publications:
The discovery holds promise for treating conditions such as Parkinson's disease, diabetes, multiple sclerosis, cardiac disease and spinal cord injuries.
About our Lab Research
Our team of research associates, postdoctoral fellows, MD/PhD students and research assistants is interested in studying some of the fundamental questions in early embryo development and stem cell biology. We use state-of-the-art technologies in molecular biology, biochemistry, cell biology, and embryology to understand genetic and epigenetic mechanisms governing the developmental program. The basic research conducted in the lab provides new insights into biology of totipotent and pluripotent cells and reprogramming of aged somatic cells to the totipotency and pluripotency by somatic cell nuclear transfer (SCNT) and iPS approaches. Particularly, we are interested in the role of mitochondria and mitochondrial genome during development and aging and in reprogramming and re-setting the developmental program in experimentally created totipotent and pluripotent cells derived from aged somatic cells.