Laboratory of Dr. Charles Allen

Patched cell

Research Interests

The long-term goal of our research is to understand the functional properties of SCN neurons and how the circadian clock regulates these properties. To reach this goal we are pursuing four lines of research (click for a summary of our work in these areas): 

Cellular electrophysiology of the suprachiasmatic nucleus

Regulation of retinal input to the SCN

Role of intracellular Ca2+ as a signaling molecule in the circadian system

Characterization of the retinal ganglion cells projecting to the SCN



Find Dr. Allen's publications on PubMed


Lab Members



Mykhaylo Moldavan, Ph.D.

Mykhalo Moldavan

Senior Research Associate

Dr. Moldavan received his Bachelor of Science in Biology from Kyiv State University in Kyiv, Ukraine and his Ph.D. in Physiology from the Bogomoletz Institute of Kyiv, Ukraine. He is studying the modulation, by presynaptic receptors, of optic nerve signaling to the suprachiasmatic nucleus. More information.



Lauren M. Hablitz, Ph.D.  

Postdoctoral ResearcherLauren Hablitz

Dr. Hablitz received her Bachelor of Science in Biology from The Pennsylvania State University in 2010. She then earned her Ph.D. at The University of Alabama at Birmingham in Cell, Molecular, and Developmental Biology in 2015. She is currently studying the role of glial cells in modulating circadian rhythms.



Nate Klett, B.S.

Graduate Student ResearcherNate Klett

Nate received his Bachelor of Science in Neuroscience from University of Pittsburgh in 2008.  Later that year, Nate enrolled in OHSU's Neuroscience Graduate Program, and has since joined the laboratory of Dr. Charles Allen.  Nate's thesis project
examines the intracellular chloride concentration in neurons of the suprachiasmatic nucleus.



Olga Cravetchi, M.S., M.D.

Olga Cravetchi, M.S., M.D.

Research Assistant II

Olga Cravetchi, Research Assistant II, joined the lab in August 2011. She received her MS in Experimental Medicine in 2009 from University of Alberta, Edmonton, Alberta, Canada and also got a MD in Pediatrics from the State University of Medicine, Moldova. Her work assists all projects that run in the laboratory. She performs neuronal cell cultures for intracellular imaging, molecular biology experiments as well as protein expression analysis using Western blot and IHC.

Allen Lab August 2015
The Allen Lab, August 2015.  Misha Moldavan, Olga Cravetchi, Nate Klett, Lauren Hablitz