Research Focus: One unique aspect of in vivo dynamic contrast enhanced (DCE) MRI lies in its indirect detection of contrast reagent (CR), via proton signal from water molecules. Since CR and water never distribute equally in vivo, this calls for the studies of water exchange. Currently, our research is focused on water exchange effect on DCE-MRI quantification and its pathological as well as physiological applications.
Biography: Dr. Li received his Bachelors of Science degree from the University of Science & Technology of China, Hefei, Anhui, PRC in 1989. He pursued his graduate studies in New York where he received a Doctoral degree from the State University of New York, Stony Brook in 1999. Since 2005, Dr. Li has served as an Assistant Scientist at the AIRC. Since 2008, he has served as a Collaborative Scientist in the Division of Reproductive Sciences at the Oregon National Primate Research Center (ONPRC) in Beaverton, Oregon.
Key Publications:Li X, Rooney WD, Springer CS. A unified magnetic resonance imaging pharmacokinetic theory: intravascular and extracellular contrast reagents. Magn Reson Med 54:1351-1359, 2005. [ Erratum: Magn Reson Med 55 (2006) 1217].
Li X, Springer CS, Jerosch-Herold M. "First-Pass DCE-MRI with Extravasating CR: Evidence for Human Myocardial Capillary Recruitment in Adenosine-Induced Hyperemia." NMR Biomed 22: 148-157, 2009.