Research Focus: One major, NIH-funded project is to use Shutter-Speed Model dynamic contrast-enhanced (DCE) MRI technique which was developed in this laboratory to improve breast cancer diagnostic accuracy and reduce unnecessary biopsy procedures on women with benign lesions. Another major project is to use multiple functional MR methods (DCE-MRI, vessel size index MRI, diffusion-weighted MRI, and proton MR spectroscopy) for early prediction of breast cancer response to chemotherapy and for accurate assessment of residual cancer after therapy for optimum surgical planning/decision. Other ongoing or planned oncologic MR research studies cover the topics of soft tissue sarcoma, head & neck cancer, liver cancer, and colon-rectal cancer.
Biography: Wei Huang obtained his bachelor's degree in 1988 from Fudan University, Shanghai/China, PhD degree in Physical Chemistry in 1994 from State University of New York at Stony Brook. He was a postdoctoral fellow in NIH from 1995 to 1998. Wei Huang has more than eighteen years experience in in vivo MR research. Wei Huang's main MR research interest was in the field of neurodisorders when he was an assistant professor in the Radiology Department at Stony Brook from 1998 to 2003. His focus switched to cancer research when he worked for Memorial Sloan-Kettering Cancer Center from 2003-2008. Currently, Wei Huang's main effort is in oncologic MR research, applying advanced MR techniques for early and accurate cancer detection and monitoring therapeutic response.
Huang W, Li X, Morris EA, Tudorica LA, Seshan VE, Rooney WD, Tagge I, Wang Y, Xu J, Springer CS. The magnetic resonance shutter speed discriminates vascular properties of malignant and benign breast tumors in vivo. Proc Natl Acad Sci 2008; 105: 17943-17948.
Bartella L, Morris EA, Dershaw DD, Liberman L, Thakur SB, Moskowitz SC, Guido J, Huang W. Proton MR Spectroscopy using choline signal as malignancy marker improves positive predictive value for the diagnosis of breast cancer - A preliminary study. Radiology 2006; 239: 686-692.