Pre-implantation Genetic Diagnosis

Preimplantation Genetic Diagnosis (PGD) allows us to analyze embryos for specific genetic disorders.  Specially trained embryologists in our lab remove (biopsy) one or two cells of the fertilized egg before it implants in the uterine wall.  Our experts then examine these cells to see if they carry the specific genes indicating disorder.  After the genetic diagnosis is complete, the embryo(s) that is determined to be free of the specific genetic disorder is transferred to the patient. We follow the same process as used with conventional IVF.

We provide PGD for patients who have:

  • Experienced recurrent pregnancy loss
  • Experienced unexplained IVF failure
  • Risk of transmitting X-linked or single gene disorders

Some of the single-gene disorders that can be diagnosed using PGD include:

  • Cystic fibrosis
  • LeschNyhan
  • Tay Sachs
  • Huntington's disease
  • Myotonic dystrophy
  • Spinal cerebellar ataxia
  • Spinal muscular atrophy-1 (SMA-1)
  • Duchenne muscular dystrophy
  • VCFS/DiGeorge syndromes
  • Fanconi anemia-A
  • SCIDS (autosomal recessive mutation of ADA)
  • Hemophilia A
  • RH incompatibility
  • Human Platelet Antigen (PLA-1)

Complete list of genetic diseases that can be tested at the Genesis Genetic Institute.