Peter Kurre Lab

Program in Hematopoietic Stem Cell Biology

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The KurreLab focuses on the study of hematopoietic stem cells and the bone marrow microenvironment. Using a model of Fanconi anemia, we study hematopoiesis and explore retroviral delivery for the stable genetic modification of long-lived stem cells as a treatment for bone marrow failure. Our leukemia-focused work aims to understand the role of membrane -derived microvesicles in the crosstalk between leukemic cells and their surrounding microenvironment and its impact on extrinsic drug resistance.