Charles Keller Lab
The Keller Laboratory studies the driving mechanisms and therapeutic targets in the childhood muscle cancers, alveolar rhabdomyosarcoma and embryonal rhabdomyosarcoma, and the childhood brain tumor, medulloblastoma.
Latest from the Keller Lab Blog
Childhood cancer foundations partner towards a clinical trial with OHSU-Doernbecherpress release adapted from The Doernbecher Connection (Winter 2014, Issue 3)
Beech Grove, KY; Miami, Florida; Portland, OR
Two children who found worldwide acclaim through their inspirational battles with childhood cancer continue to make an impact. The Thumbs Up for Lane Goodwin Childhood Cancer Foundation and the Live Like Bella™ Foundation for Childhood Cancer have announced the joint funding of the $180,000 “Lane-Bella Project.” The Lane-Bella Project, under the direction of Charles Keller, M.D., an associate professor of pediatrics at Oregon Health and Science University Doernbecher Children’s Hospital and a member of the OHSU Knight Cancer Institute, is a new set of studies to prepare for a clinical trial focusing on Rhabdomyosarcoma, the aggressive childhood cancer that took the lives of both Lane Goodwin, age 13, and Bella Rodriguez-?Torres, age 10. The study will focus on finding an antibody to stop the growth of childhood muscle cancers. Once preclinical studies are complete, children around the world might benefit from these new innovations as early as 2015. The trial is the largest project funded by the two foundations, with each contributing $90,000, and includes the $20,000 donation that the MLB National League Rookie of the Year, Marlins Pitcher Jose Fernandez, directed to the Live Like Bella™ after receiving the honor.
“I want to help children with cancer. I’m proud to support life changing research to help find a cure.” ?Jose Fernandez
Gifts designated for the Lane-Bella Project will also be applied to the historic Knight Cancer Challenge. Nike co-founder Phil Knight and his wife, Penny, will match OHSU’s fundraising efforts if it meets its $500 million fundraising goal by the end of 2015, totaling $1 billion to advance the Knight Cancer Institute’s vision to end cancer as we know it. To learn more, visit ohsu.edu/knightcancerchallenge.
The Thumbs Up for Lane Goodwin Childhood Cancer Foundation works in memory of its founder, Lane Goodwin. It funds cuttng edge research to find a cause and a cure for childhood cancers, empowers families to advocate on behalf of their children, and provides financial assistance to families through the “Changing Lanes” program. For more information, visit www.ThumbsUpForLane.org
The Live Like Bella™ Foundation was founded in memory of Bella Rodriguez-?Torres. It funds innovatve pediatric cancer research, provides recreatonal support for families with children in treatment and assists families who have lost a child to cancer.
For more informaton, visit
ALSF REACH grant highlighted in Portland Business JournalMegan's project, sponsored by the Alex's Lemonade Stand Foundation, was highlighted today by Elizabeth Hayes in the Portland Business Journal. For project updates, click here.
Nanocourse publicationCongratulations to the 2012 Participants of the OHSU Pediatric Cancer Nanocourse whose peer-reviewed commentary, "A Diffuse Intrinsic Pontine Glioma Roadmap: Guiding Research Toward a Cure" is published in the journal, Pediatric Blood & Cancer.
It should be emphasized that this scholarly work is that of members of the community: parents, survivors and students. We are grateful to have been able to work with this talented and insightful group of individuals.