Ocular Immunology Lab

The Ocular Immunology Laboratory at Casey Eye Institute offers retinal autoantibody tests for cancer-associated retinopathy (CAR), melanoma-associated retinopathy (MAR), autoimmune retinopathy and optic neuropathy. The lab is directed by Grazyna Adamus, Ph.D., Professor of Ophthalmology.

Offered Tests

For Cancer-Associated Retinopathy (CAR), Melanoma-Associated Retinopathy (MAR) and Autoimmune Retinopathy in Serum and/or ocular fluids:

  • Western blot for anti-retinal autoantibodies, which includes anti-enolase, anti-recoverin and other autoantibodies serum
  • Immunohistochemistry for anti-retinal autoantibodies
  • Western blot for anti-retinal autoantibodies, which includes anti-enolase and anti-recoverin autoantibodies in ocular fluids (vitreous, subretinal fluid)

For Autoimmune Optic Neuropathy in Serum and/or Cerebrospinal Fluid

  • Western blot for anti-optic nerve autoantibodies in the serum
  • Western blot for anti-optic nerve autoantibodies in CSF

Indications for Testing

Ocular Immunology Lab Indications for Testing chart high resolution 2

How to Submit a Specimen

  1. Submit the completed Test Requisition Form with specimen that must include all of the following items
  2. Patient's name, gender and birthday
  3. Specimen collection date
  4. Referring clinic or physician name and contact information, including fax number
  5. Clinical history and findings
  6. Name of test requested
  7. Pre-payment - check or major credit card accepted, we do not bill insurance
Note: A specimen will not be processed without a fully completed requisition form. 

Specimen Requirements

  • Please do not send or freeze whole blood
  • Draw blood in red top tubes (serum gel tubes are also acceptable) 
  • Spin down and send serum in plastic vials
  • Serum (3 to 5 ml)
  • Fluids (0.5 ml)
  • Serum can be stored in a refrigerator no longer than 7 days until shipping
  • Do not ship on Friday 

Anticipated turnaround time for routine cases is two to four weeks.

Specimen can be shipped refrigerated with cold packs or at ambient temperature together with the complete test requisition form and pre-payment by overnight mail to:

Dr. Grazyna Adamus
Ocular Immunology Laboratory, OHSU
Biomedical Research Building, Room 253
3181 SW Sam Jackson Park Road
Portland, OR 97239, USA

Phone: 503-418-2543
Fax: 503-418-2541