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A chronology of the “fetal origins of disease” research theme at OHSU

1959
Herbert Griswold, M.D., created Heart Research Laboratory to be housed in the not yet completed Medical Research Building.
1961
James Metcalfe, M.D., hired from Harvard Medical School as first director of the Heart Research Laboratory. The Heart Research Laboratory studied pregnancy and fetal development long before the early origins of disease was discovered.
1988
David Barker, M.D., Ph.D., and Kent Thornburg, Ph.D., met at an international scientific meeting.
1994
Heart Research Center began as official entity. Dr. Kent Thornburg named director.
1994
First Annual HRC Lecture: Born Bigger … Live Longer, Presented by Dr. David Barker, Environmental Epidemiology Unit, University of Southampton.
1997 - present
Thornburg program project grant funded by NICHD: Maternofetal Signaling and Lifelong Consequences. Current project directors are Kaul, Giraud, Thornburg and Stork.
1999
Kent Thornburg convened an international conference on Fetal Origins of Adult Disease in San Diego, CA. The group that became the DOHaD council met there to organize the idea of an international organization.
2003
Barker joined OHSU Heart Research Center and faculty at OHSU. His interest in Oregon is due to the long track record on the study of pregnancy and fetal development.
2003
Kent Thornburg elected as honorary member of the Society for the Natal Effects of Health on Adults, India.
2003
The International Society for the Developmental Origins of Health and Disease was formed; Thornburg and Barker on Council. The society now includes over 500 members from 35 countries.
2003
Kevin Grove, Ph.D., awarded NIH grant to determine how brain chemistry in early life affects abnormal body weight management during adulthood.
2005
David Barker awarded Danone International Nutrition Award.
2006
David Barker awarded Arzobispo Gandarillas Medal, Catholic University of Chile.
2006-2008
Oregon Women’s Study — funded by Northwest Health Foundation, Collins Medical Trust and private donors. A study of 150 women of childbearing age in Klamath Falls, OR to determine how food intake of pregnant women influences growth patterns of fetus and later the infant through its first year. Cynthia Morris, Ph.D., PI.
2007
HRC DOHaD Group Formed, Susan Bagby, M.D., Director.
2007
Kevin Grove awarded NIH grant to study maternal high fat diet and health of offspring.
2007
Thornburg joined Finland Epidemiology Group.
2007
David Barker awarded Foundation Ipsen Prize, Paris.
2009
HRC Education Committee formed to share knowledge, create curriculum and improve health of adolescents. MoU signed with Wilsonville-West Linn School District.
2009
Thornburg and Barker collaborate with researchers at Université de la Méditerranée, Marseilles, France, to study childhood growth as a predictor of abnormal heart growth in young adults.
2010
NIA funds Barker/Thornburg collaborative project with Finland to determine how maternal nutrition and childhood living conditions and growth predict physical and mental health in the elderly.
2010
HRC hosted meeting of international experts to determine optimal pre-conception and prenatal nutrition for Oregon women and to explore potential interventions for Oregon, sponsored by the March of Dimes.
2010
Collaborations formed with University of Colorado Health Sciences Center.
2010

Grove, Thornburg & Friedman awarded NIH funds to study the impact of maternal diet on development of a healthy fetus.

2010

David Barker awarded Agnes Higgins Award, March of Dimes.

2011
Co-hosted with PSU meeting to educate local public health leaders about the public health implications of DOHaD and to explore policy changes to improve public health. Funded by Northwest Health Foundation.
2011
David Barker awarded Richard Doll Prize, International Epidemiological Association.
2012

Bob and Charlee Moore Institute for Nutrition & Wellness founded.

Moore Institute's founding three projects selected.