Xiangshu Xiao, PhD
Associate Professor, Physiology and Pharmacology
Physiology & Pharmacology
Program in Molecular & Cellular Biosciences
Background & Education
Postdoc 2007, UT Southwestern Medical Center, Dallas, TX
Ph.D. 2005, Purdue University, West Lafayette, IN
M.Sc. 2001, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai
B.S. 1998, Beijing Medical University
Cancer chemical biology. Please go here for more details.Publications
2. Kang, X.; Lu, Z.; Cui, C.; Fan, Y.; Dong, B.; Han, X.; Xie, X.; Tyner, J. W.; Coligan, J. E.; Collins, R. H.; Xiao, X.; You, J. M.; Zhang, C. C. “The ITIM-containing receptor LAIR1 is essential for acute myeloid leukemia development” Nat. Cell Biol., 2015, 17, 665-677 (Highlighted in UT Southwestern News, ScienceDaily, MedicalXpress, Bionews-TX, Biocentury Innovations (formerly SciBX) and BioQuick News).
3. Chao, B.; Li, B. X.; Xiao, X.* “The chemistry and pharmacology of privileged pyrroloquinazolines” MedChemComm, 2015, 6, 510-520.
4. Xie, F.; Li, B. X.; Alkayed, N. J.; Xiao, X.* “Synthesis of 14,15-EET from Arachidonic Acid Using Urea-Hydrogen Peroxide as the Oxidant” Synthetic Commun., 2015, 45, 105-110.
5. Li, B. X.; Xie, F.; Fan, Q.; Barnhart, K. M.; Moore, C. E.; Rheingold, A. L.; Xiao, X.* “Novel Type of Prodrug Activation through a Long-range O,N-Acyl Transfer: a Case of Water-Soluble CREB Inhibitor ” ACS Med. Chem. Lett., 2014, 5, 1104-1109.
The Xiao group at Program in Chemical Biology, Department of Physiology and Pharmacology, Knight Cancer Institute at Oregon Health & Science University (OHSU) invites outstanding applicants for a postdoctoral position in cancer chemical biology. The candidate will be part of a multidisciplinary team of investigators with expertise in drug discovery, organic synthesis, computational chemistry, biochemistry, molecular biology and cell biology. The candidate will be working in an exciting area of cancer chemical biology. Specifically, s/he will be responsible for the design, synthesis and evaluation of small molecules as novel cancer therapeutics and chemical tools to elucidate signaling mechanisms. In addition, the candidate should be capable of analyzing the data and writing up of the results into appropriate manuscript form for peer-reviewed publications. The candidate will have ample opportunities for participating grant writing, seminar presentation and other professional development. The candidate must show demonstrated capability to work within a highly collaborative environment. A Ph.D. in organic chemistry, medicinal chemistry or other related discipline is required. Salary will be competitive ($47,484 and up). Highly motivated individuals should send their current CV and names and contact information of three references to: Prof. Xiangshu Xiao, Ph.D. by email email@example.com. OHSU is an equal opportunity, affirmative action institution.
Department of Physiology and Pharmacology
Knight Cancer Institute
Oregon Health & Science University
3181 SW Sam Jackson Park Rd
Portland, OR 97239
Phone: (503) 494-4748