Xiangshu Xiao, PhD


Primary Affiliation

Associate Professor, Physiology and Pharmacology

Program Affiliation

Physiology & Pharmacology

Cancer Biology

Program in Molecular & Cellular Biosciences

Background & Education

Postdoc 2007, UT Southwestern Medical Center, Dallas, TX

Ph.D. 2005, Purdue University, West Lafayette, IN

M.Sc. 2001, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai

B.S. 1998, Beijing Medical University


Cancer chemical biology.  Please go here for more details.

Meet the Lab

Useful Links

Selected Publications

1. Xie, F.;Li, B. X.;Kassenbrock, A.;Xue, C.;Wang,X.;Qian, D. Z.;Sears, R. C.;Xiao, X.*"Identification of a Potent Inhibitor of CREB-Mediated Gene Transcription withEfficacious in Vivo Anticancer Activity" JMed. Chem., 2015, 58, 5075–5087. (Highlighted in Biocentury Innovations (formerly SciBX), Labbase News)

xiao 1

Kang, X.; Lu, Z.; Cui, C.; Fan, Y.; Dong, B.; Han, X.; Xie, X.; Tyner, J. W.; Coligan, J. E.; Collins, R. H.; Xiao, X.; You, J. M.; Zhang, C. C. “The ITIM-containing receptor LAIR1 is essential for acute myeloid leukemia development” Nat. Cell Biol., 2015, 17, 665-677 (Highlighted in UT Southwestern News, ScienceDaily, MedicalXpress, Bionews-TX, Biocentury Innovations (formerly SciBX) and BioQuick News).


3. Chao, B.; Li, B. X.; Xiao, X.*The chemistry and pharmacology of privileged pyrroloquinazolinesMedChemComm, 2015, 6, 510-520.
xiao 5


4. Xie, F.; Li, B. X.; Alkayed, N. J.; Xiao, X.* “Synthesis of 14,15-EET from Arachidonic Acid Using Urea-Hydrogen Peroxide as the Oxidant” Synthetic Commun., 2015, 45, 105-110.

xiao 4

5. Li, B. X.; Xie, F.; Fan, Q.; Barnhart, K. M.; Moore, C. E.; Rheingold, A. L.; Xiao, X.* “Novel Type of Prodrug Activation through a Long-range O,N-Acyl Transfer: a Case of Water-Soluble CREB Inhibitor ” ACS Med. Chem. Lett., 2014, 5, 1104-1109.

xiao 5







Department of Physiology and Pharmacology
Knight Cancer Institute
Oregon Health & Science University
3181 SW Sam Jackson Park Rd
Portland, OR  97239
Phone: (503) 494-4748