OHSU

Margo Haygood

Margo Haygood

Email:
Phone: 503 748-1993
Fax: 503 748-1464
Website: Haygood Research Group and Philippine Mollusk Symbiont International Cooperative Biodiversity Group (PMS-ICBG)

 

Current Appointments

Professor, Environmental and Biomolecular Systems
OGI Distinguished Professor in Marine and Biomolecular Systems, Division of Environmental and Biomolecular Systems
Affiliate Scientist, Center for Coastal Margin Observation and Prediction

 

Education

B.A. magna cum laude, History and Science, Harvard University, 1976
Ph.D., Marine Biology, Scripps Institution of Oceanography, University of California, San Diego, 1984
Molecular Evolution Workshop, Marine Biological Laboratory, Woods Hole, 1991

 

Biography

  • Scripps Institution of Oceanography, University of California, San Diego,Graduate Student, with Kenneth H Nealson, 1977-79; 1981-84
  • University of Tokyo, Misaki Marine Biological Station, Monbusho Scholar, 1979-81
  • University of Washington, Postdoctoral Fellow with Mary E. Lidstrom, Dept. of Microbiology and Immunology, 1984-85
  • Office of Naval Research, Scientific Officer, Biological Sciences Division, Molecular Biology Program, 1985-86
  • Scripps Institution of Oceanography, University of California, San Diego; Assistant Professor, 1987-1995; Associate Professor, 1995-2002; Professor, 2002-2006

 

Research Interests

Environmental microbiology; bacterial physiology; bacterial evolution, marine biotechnology

 

Selected Publications

Roe, K. L.; Barbeau, K.; Mann, E. L.; Haygood, M. G. (2012) Acquisition of iron by Trichodesmium and associated bacteria in culture. Environ. Microbiol., 14, 1681-1695. (DOI: 10.1111/j.1462-2920.2011.02653.x)

Lin, Z.; Flores, M.; Forteza, I.; Henriksen, N. M.; Concepcion, G. P.; Rosenberg, G.; Haygood, M. G.; Olivera, B. M.; Light, A. R.; Cheatham, T. E.; Schmidt, E. W. (2012) Totopotensamides, polyketide-cyclic peptide hybrids from a mollusk-associated bacterium Streptomyces sp. J. Nat. Prod., 75, 644-649. (DOI: 10.1021/np200886x)

Dias, G. M.; Thompson, C. C.; Fishman, B.; Naka, H.; Haygood, M. G.; Crosa, J. H.; Thompson, F. L. (2012) Genome sequence of the marine bacterium Vibrio campbellii DS40M4, isolated from open ocean water. J. Bacteriol., 194, 904. (DOI: 10.1128/jb.06583-11)

Betcher, M. A.; Fung, J. M.; Han, A. W.; O'Connor, R.; Seronay, R.; Concepcion, G. P.; Distel, D. L.; Haygood, M. G. (2012) Microbial distribution and abundance in the digestive system of five shipworm species (Bivalvia: Teredinidae). PLoS One, 7, e45309. (DOI: 10.1371/journal.pone.0045309)

Lin, Z.; Reilly, C. A.; Antemano, R.; Hughen, R. W.; Marett, L.; Concepcion, G. P.; Haygood, M. G.; Olivera, B. M.; Light, A.; Schmidt, E. W. (2011) Nobilamides A-H, long-acting transient receptor potential vanilloid-1 (TRPV1) antagonists from mollusk-associated bacteria. J. Med. Chem., 54, 3746-3755. (DOI: 10.1021/jm101621u)

Donia, M. S.; Fricke, W. F.; Partensky, F.; Cox, J.; Elshahawi, S. I.; White, J. R.; Phillippy, A. M.; Schatz, M. C.; Piel, J.; Haygood, M. G.; Ravel, J.; Schmidt, E. W. (2011) Complex microbiome underlying secondary and primary metabolism in the tunicate-Prochloron symbiosis. Proc. Natl. Acad. Sci. U. S. A., 108, E1423-E1432, SE1423/1421-SE1423/1424. (DOI: 10.1073/pnas.1111712108)

Trindade-Silva, A. E.; Lim-Fong, G. E.; Sharp, K. H.; Haygood, M. G. (2010) Bryostatins: biological context and biotechnological prospects. Curr. Opin. Biotechnol., 21, 834-842. (DOI: 10.1016/j.copbio.2010.09.018)

Sandy, M.; Han, A.; Blunt, J.; Munro, M.; Haygood, M.; Butler, A. (2010) Vanchrobactin and anguibactin siderophores produced by Vibrio sp. DS40M4. J. Nat. Prod., 73, 1038-1043. (DOI: 10.1021/np900750g)

Lin, Z.; Antemano, R. R.; Hughen, R. W.; Tianero, M. D. B.; Peraud, O.; Haygood, M. G.; Concepcion, G. P.; Olivera, B. M.; Light, A.; Schmidt, E. W. (2010) Pulicatins A-E, neuroactive thiazoline metabolites from cone snail-associated bacteria. J. Nat. Prod., 73, 1922-1926. (DOI: 10.1021/np100588c)

Yang, J. C.; Madupu, R.; Durkin, A. S.; Ekborg, N. A.; Pedamallu, C. S.; Hostetler, J. B.; Radune, D.; Toms, B. S.; Henrissat, B.; Coutinho, P. M.; Schwarz, S.; Field, L.; Trindade-Silva, A. E.; Soares, C. A. G.; Elshahawi, S.; Hanora, A.; Schmidt, E. W.; Haygood, M. G.; Posfai, J.; Benner, J.; Madinger, C.; Nove, J.; Anton, B.; Chaudhary, K.; Foster, J.; Holman, A.; Kumar, S.; Lessard, P. A.; Luyten, Y. A.; Slatko, B.; Wood, N.; Wu, B.; Teplitski, M.; Mougous, J. D.; Ward, N.; Eisen, J. A.; Badger, J. H.; Distel, D. L. (2009) The complete genome of Teredinibacter turnerae T7901: an intracellular endosymbiont of marine wood-boring bivalves (shipworms). PLoS One, 4. (DOI: 10.1371/journal.pone.0006085)

Lopanik, N. B.; Shields, J. A.; Buchholz, T. J.; Rath, C. M.; Hothersall, J.; Haygood, M. G.; Hakansson, K.; Thomas, C. M.; Sherman, D. H. (2008) In vivo and in vitro trans-acylation by BryP, the putative bryostatin pathway acyltransferase derived from an uncultured marine symbiont. Chem. Biol. (Cambridge, MA, U. S.), 15, 1175-1186. (DOI: 10.1016/j.chembiol.2008.09.013)

Lim-Fong, G. E.; Regali, L. A.; Haygood, M. G. (2008) Evolutionary relationships of "Candidatus endobugula" bacterial symbionts and their Bugula bryozoan hosts. Appl. Environ. Microbiol., 74, 3605-3609. (DOI: 10.1128/aem.02798-07)