BMB Graduate Students
Amber M. Jones Brunette
Chiara Del Piccolo
Chiara Del Piccolo grew up in Basalt, Colorado. She attended Williams College in Williamstown, MA, where she double-majored in Biology and Political Science, with an emphasis on International Relations. She also spent her junior year of college studying abroad at Oxford University (Exeter College). At Williams, Chiara participated in Cross-Country and Track and Field, where she won the Division III Cross-Country National Meet as a sophomore and was an All-American in the 10,000m run as a freshman. After graduation, she moved to Portland to start graduate school at OHSU and joined the lab of Dr. Michael Chapman, where she has had the opportunity to bring together the study of protein structure and dynamics with computational analysis. In the Chapman Lab, she is working to develop new computational methods that enable the integration of complementary information from emerging experimental approaches in NMR spectroscopy, cryo-electron microscopy, and X-ray crystallography. In the future, she hopes to pursue a career as an academic researcher in the quantitative biosciences.
Ahn, J. W., Falahee, B., Del Piccolo, C., Vogel, M., &Bingemann, D. (2013). Are rare, long waiting times between rearrangement events responsible for the slowdown of the dynamics at the glass transition? Journal of Chemical Physics, 138(12).
Xin Wang, Ph.D., Chiara W. Del Piccolo, Bruce M. Cohen, M.D., Ph.D., Edgar A. Buttner, M.D., Ph.D. (2014). Transient Receptor Potential M (TRPM) Channels Mediate Clozapine-induced Phenotypes in Caenorhabditis elegans. Journal of Neurogenetics. 28 (86-97).
Greg grew up in the heartland and attended Iowa State University in Ames, Iowa, his hometown. He graduated with a degree in Biology in 2010, and as many young people these days, was unsure of his next step. However, he did know that he had an indelible curiosity and a nagging incapacity to just leave well enough alone, thus he knew science was for him. He soon landed the prestigious position of Research Associate at his alma matter in Genetics, Development, and Cell Biology. There, he studied mechanisms of neuronal diversity in the mammalian retina, specifically with regards to how retinal ganglion cells are produced and what makes certain ganglion cells not like those other ganglion cells. It was interesting work but was focused on whole-cell and even whole tissue-mechanisms, and Greg wanted to know exactly what was happening down to the atom. He has always had a fascination with chemistry, and a passion for biology, thus he knew that biochemistry was indeed his cup of tea. He escaped from the Midwest and landed in Portland for graduate school in the fall of 2012. He chose Dr. Show-Ling Shyng as a mentor and is now happily studying atomic-level mechanisms of KATP channel trafficking and gating regulation. Upon graduation, he hopes to pursue a life in academic science by first landing a post-doc somewhere studying more atomic-level mechanisms, likely in another membrane protein, as he has decided that membrane proteins are the bees-knees.
Nathan was born and raised in Portland and attended the University of Oregon in Eugene. While at UO he worked in cognitive neuroscience in the lab of Dr. Michael Anderson and graduated with a BS in Psychology in 2005. Nathan intended to pursue a doctorate in neuroscience after finishing his undergrad but felt that he needed a stronger foundation in cellular biology and biochemistry to proceed, so he decided to attend Portland State University to further his undergraduate education. While at PSU his interest shifted to Biochemistry.
In 2009 Nathan started the PMCB program at OHSU, joining the lab of Hans-Peter Bächinger in 2010. The Bächinger lab employs approaches broadly from structural and biophysical, to organismal level biology to examine the complex and unique cellular machinery required for folding of collagen, which is involved in the etiology of connective tissue disorders. Nathan's project involves biochemically characterizing post-translational modifications of basement membrane collagen, underlying all epithelial cells, and to examine their role in protein-protein interactions.
After graduating, Nathan plans to pursue a post-doctoral fellowship in biochemistry outside of the beautiful pacific northwest, and expand the scale of his biological understanding, through education in bioinformatics, systems biology, or proteomics.
Sigrid graduated with a Bachelor's degree in Physics from University of Oslo in 2014. She spent one year of her undergraduate studies as an exchange student at the University of Oregon where she took classes and worked in the Parthasarathy lab. She assisted a graduate student in his research project that involved calculating the rigidity of biological membranes using light sheet fluorescence imaging. Sigrid joined the Baconguis lab June 2015 as a PhD student and her research is focused on the function and structure of sodium channels.
BS - Molecular Cell & Developmental Biology, University of California Santa Cruz
Jon's research interests include protein memory, protein biochemistry, and protein-nucleic acid interactions.