OHSU

Jules Panksepp

Postdoctoral Fellow

JBP pictEducation

B.Sc. Biology and Neuroscience, Bowling Green State University, 2000
M.Sc. Biology, Bowling Green State University, 2003
Ph.D. Neuroscience, University of Wisconsin, 2009 

Research Areas

neuroethology, social neuroscience, mechanisms of shared experience, evolutionary biology 

Research Description

My experiments are concerned with exploring the biological substrates underlying subjective states in animals. In particular, I am interested in characterizing the neural mechanisms that motivate individuals to engage one another within the context of social interaction. In previous work, I developed a model of adolescent sociability using inbred strains of mice that identified stable, genetically based differences in social motivation, social reward and emotional responsiveness towards conspecifics. Currently, I am employing a 'poor-man's' approach for monitoring metabolic activity in the brain of juvenile mice. This methodology offers 1-2 orders of magnitude better spatial-volumetric resolution than current mirco-PET technologies. From a basic science perspective, these studies provide an opportunity to comprehensively define the mammalian social brain at the neural circuit level; from a translational science perspective, these studies serve as a framework for developing more realistic pre-clinical models of human psychosocial disorders

Publications

Panksepp J and Panksepp JB (2013) Toward a cross-species understanding of empathy. Trends in Neuroscience. 36:489-496.

Kennedy BC, Panksepp JB, Runckel PA, and Lahvis GP (2012) Social influences on morphine conditioned place preference in juvenile BALB/cJ and C57BL/6J mice. Psychopharmacology 219: 923-932.

Kennedy BC*, Panksepp JB*, Wong JC, Krause E, and Lahvis GP (2011) Age-dependent and strain-dependent influences of morphine on social approach behavior in mice. Behavioral Pharmacology 22:147-159. *co-first authors.

Panksepp JB and Lahvis GP (2011) Rodent empathy and affective neuroscience. Neuroscience and Biobehavioral Reviews 35:1864-1875.

Huber R, Panksepp JB, Nathaniel T, Alcaro A, Panksepp J (2011) Drug-sensitive reward in crayfish: An invertebrate model system for the study of SEEKING, reward, addiction, and withdrawal. Neuroscience and Biobehavioral Reviews 35:1847-1853.

Chen Q*, JB Panksepp* & GP Lahvis (2009) Empathy is moderated by genetic background in mice. PLoS ONE 4: e4387. * co-first authors.

Panksepp JB, JC Wong, BC Kennedy & GP Lahvis (2008) Differential entrainment of a social rhythm in adolescent mice. Behavioural Brain Research 195: 239-245. 

Panksepp JB, KA Jochman, JU Kim, JJ Koy, ED Wilson, Q Chen, C Wilson & GP Lahvis (2007) Affiliative behavior, ultrasonic communication and social reward are influenced by genetic variation in adolescent mice. PLoS ONE 2: e351. 

Panksepp JB & GP Lahvis (2007) Social reward among juvenile mice. Genes, Brain and Behavior 6: 661-671. 

Hernandez PJ, ME Andrzejewski, K Sadeghian, JB Panksepp & AE Kelley (2005) AMPA/Kainate, NMDA, and dopamine D1 receptor function in the nucleus accumbens core: A context-limited role in the encoding and consolidation of instrumental memory. Learning and Memory 12: 285-295. 

Gammie SC, NS Hasen, TA Awad, AP Auger, HM Jessen, JB Panksepp & AM Bronikowski (2005) Gene array profiling of large hypothalamic CNS regions in lactating and randomly cycling virgin mice. Brain Research Molecular Brain Research 139: 201-211. 

Panksepp JB & R Huber (2004) Ethological analyses of crayfish behavior: A new invertebrate system for measuring the rewarding properties of psychostimulants. Behavoural Brain Research 153: 171-180. 

Panksepp J, C Nocjar, J Burgdorf, JB Panksepp & R Huber (2004) The role of emotional systems in addiction: A neuroethological perspective. In: Bevins and Bardo (eds.) Motivational Factors in the Etiology of Drug Abuse. University of Nebraska Press: Lincoln. pp. 85-126. 

Panksepp JB, Z Yue, C Drerup & R Huber (2003) Amine neurochemistry and aggression in crayfish. Microscopy Research and Technique 60: 360-368. 

Panksepp JB & R Huber (2002) Chronic alterations in serotonin function: Dynamic properties in agonistic behavior of the crayfish, Orconectes rusticus. Journal of Neurobiology 50: 276-290. 

Panksepp J, JR Moskal, JB Panksepp & R Kroes (2002) Comparative approaches in evolutionary psychology: Molecular neuroscience meets the mind. Neuroendocrinology Letters 23: 105-115. 

Huber R, A Daws, S Tuttle & JB Panksepp (2002) Quantitative techniques for the study of crayfish aggression. In: Wiese (ed.) Physiology of the Crustacean Nervous System. Springer: New York. pp. 186-201. 

Huber R, JB Panksepp, Z Yue, A Delago & P Moore (2001) Dynamic interactions of behavior and amine neurochemistry in acquisition and maintenance of social rank in crayfish. Brain, Behavior and Evolution 57: 271-282. 

Panksepp J & JB Panksepp (2001) A continuing critique of evolutionary psychology: Seven sins for seven sinners, plus or minus two. Evolution and Cognition 7: 56-80. 

Panksepp J & JB Panksepp (2000) The seven sins of evolutionary psychology. Evolution and Cognition 6: 108-131.

Page last updated: November 5, 2013