Pulpal Response to Caries and Dental Procedures

Objectives and Goals

  • Be familiar with the hydrodynamic theory of pain.
  • Be familiar with the etiologies of pain associated with different materials.
  • Be familiar with the mechanism of bacterial caused inflammation.
  • Be familiar with the general changes seen in the pulp due to aging.
  • Be able to integrate the findings in this section in your diagnosis and treatment planning.

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Hahn C, Falkler WAJ. Antibodies in normal and diseased pulps reactive with microorganisms isolated from deep caries. J Endodon 1992;18(1):28-31.

Takamori K.  A histopathological and immunohistochemical study of dental pulp and pulpal nerve fibers in rats after the cavity preparation using Er:YAG laser.  J Endodon 2000;26(2):95-99

Schmalz G, Schuster U, Koch A, Schweikl H.  Cytotoxicity of low pH dentin-bonding agents in a dentin barrier test in vitro.  J Endodon 2001;28(3):188-192

Johnson R.B.  Effects of multiple dentinal lesions on the rat pulp.  J Endodon 2004;30(12):868-871

Olsson H, Davies J, Holst K, Schroeder U, Petersson K.  Dental pulp capping effect of Emdogain gel on experimentally exposed human pulps.  Int Endo J 2005:38;186-194

Galler K, Hiller,K, Ettl T, Schmalz G. Selective influence of dentin thickness upon cytotoxicity of dentin contacting materials. J Endodon 2005;31(5):396-399

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Brannstrom M, Vojinovic O.  Response of the dental pulp to invasion of bacteria around three filling materials.  J Dent Child 1976;43:83

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Brannstrom M.  The hydrodynamic theory of dentinal pain: Sensation in preparations, caries, and dentinal crack syndrome.  J Endodon 1986;12(10):453-457

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McClanahan SB, Turner DW, Kaminski EJ, Osetek EM, Heuer MA.  Natural modifiers of the inflammatory process in the human dental pulp.  J Endodon 1991;17(12):589-593

Jackson CR.  Pulpal evaluation of teeth restored with fixed prostheses.  J Prosth Dent 1992;67:323

Murray P, Lumley P, Smith G, Franquin J, Smith A.  Postoperative pulpal and repair responses.  JADA 2000;131:321-329

Onur M, Cehreli Z, Tasman F, Gumrukcuoglu A.  Neurotoxic effects of fifth-generation dentin adhesives on rat sciatic nerve.  J Endodon 2001;27(11):676-678

Chang Y, Yang S, Hsieh.  Regulation of matrix metalloproteinase-2 production by cytokines and pharmacological agents in human pulp cell cultures.  J Endodon 2001;27(11):679-682 

Hahn CL, Falkler WAJ, Minah GA.  Correlation between thermal sensitivity and microorganisms isolated from deep carious dentin.  J Endodon      1993;19(1):26-30.

Nixon CE, Saviano JA, King GJ, Keeling SD.  Histomorphometric study of dental pulp during orthodontic tooth movement.  J Endodon1993;19(1):13-16.

Ranly D, Thomas HF, Chen J.  Osteocalcin expression in young and aged      dental pulps as determined by RT-PCR.  J Endodon 1997;23(6):37