OHSU

Owen J.T. McCarty, Ph.D.

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Background

Dr. McCarty received his Ph.D in Chemical & Biomolecular Engineering from Johns Hopkins University with dissertation work focused on the role of platelets in cancer metastasis and thrombosis. As a Wellcome Trust Postdoctoral Fellow, he continued his research in the area of thrombosis, examining the signaling pathways governing platelet cytoskeleton reorganization, at the Department of Pharmacology, Oxford University and Centre for Cardiovascular Sciences, University of Birmingham, UK.


Summary of Current Research

Research Interests

Dr. McCarty's research is focused on understanding the interplay between cell biology and fluid mechanics in the cardiovascular system. In particular, his research into the balance between hydrodynamic shear forces and chemical adhesive interactions has great relevance to underlying processes of cancer, cardiovascular disease, and inflammation.

Research Projects

Thrombosis and Hemostasis

Research Groups

Cardiovascular and Blood Research

Vascular Biology and Vascular Tissue Engineering


Selected Publications

"A theme series on physical biology in cancer in AJP-cell," American Journal of Physiology - Cell Physiology (Vol: 306, Issue: 2, Page C77) - 2014

"Physical biology in cancer. 2. The physical biology of circulating tumor cells," American Journal of Physiology - Cell Physiology (Vol: 306, Issue: 2, Page C80-C88) - 2014

"A physical sciences network characterization of non-tumorigenic and metastatic cells," Scientific Reports (Vol: 3, ) - 2013

"Exogenous modification of platelet membranes with the omega-3 fatty acids EPA and DHA reduces platelet procoagulant activity and thrombus formation," American Journal of Physiology - Cell Physiology (Vol: 304, Issue: 3, Page C273-C279) - 2013

"Factor XII promotes blood coagulation independent of factor XI in the presence of long-chain polyphosphates," Journal of Thrombosis and Haemostasis (Vol: 11, Issue: 7, Page 1341-1352) - 2013

 

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  Email Owen McCarty

503 494-8311