Otolaryngology Clinical Trials

Our Clinical Trials

The following is a list of the ongoing clinical trials in the department of Otolaryngology-Head & Neck Surgery. If you are interested in learning more about a trial, or would like to be a participant in the trial, please contact the trial coordinator at the number or email listed. If you have questions about our research or a clinical trial, please contact us the . Each division may have ongoing clinical trials. This page is kept up to date, but trials may close with little or no notice. 

Click on the Division noted below to jump to the clinical trials that are ongoing for that group:

Pediatric Clinical Trials

The Pediatric Division of the Department of Otolaryngology-Head & Neck Surgery is currently working on the following clinical trials:

  • Genetics of ear infections (otitis media)
  • Outcomes of procedures for laryngeal cleft repair for pediatric patients with dysphagia
  • Outcomes of tympanostomy tubes for patients with Down syndrome
  • Treatment outcomes in children with hypernasal speech (velopharyngeal insufficiency)
  • How children's ears are affected by cleft palate

If you are interested in finding out more about any of these studies, or if you are interested in participating in one of these studies, please call 503 494-5350 to schedule a consultation with either Dr MacArthur or Dr Milczuk in our Pediatric Otolaryngology clinic. If you would like to know if you are eligible to participate in a study, please email

Oregon Sinus Center

Title: Determinants of Medical and Surgical Treatment Outcomes in Chronic Sinusitis

Dates: 4/1/2011-6/30/2017

Source: National Institute on Deafness and Other Communication Disorders

Description: A multi-institutional prospective cohort study to compare quality of life outcomes between medical management and endoscopic sinus surgery for chronic rhinosinusitis. A total of 976 patients will be enrolled at several tertiary care centers around the country and coordinated at OHSU. This study also evaluates olfactory function, as well as cellular and molecular expression of patients with chronic sinus disease.

Role: Dr. Timothy L. Smith. Principal Investigator

Enrollment: OHSU is the coordinating research center and all enrollment activities take place within the Oregon Sinus Center at the Center for Health and Healing during normal clinic visits by invitation only. To date, other patient enrollment sites include the Medical University of South Carolina, University of Utah, and Stanford University.

Contact: or , Research Coordinator


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Head & Neck Surgery / Cancer Clinical Trials

  • Steroid Therapy After TORS (IRB #8071) – This study is being done to determine whether steroid treatment (dexamethasone) can help manage pain and improve swallowing function following transoral robotic surgery (TORS) for head and neck cancer. 
  • VTE2 (IRB #9434) – The purpose of this study is to determine whether the routine use of lovenox (a blood thinner) reduces the incidence of blood clots (venous thromboembolism or VTE) in the legs of head and neck cancer patients after surgery.
  • IRB 16230   - A Double-Blind, Randomized, Two Arm Phase 2 Study of Nivolumab in Combination with Ipilimumab versus Nivolumab in combination with Ipilimumab placebo Squamous Cell Carcinoma of the Head and Neck (SCCHN)

If you are interested in getting more information about, or participating in, the Head & Neck Surgery / Cancer Clinical trials, email or call at 503 494-5355.


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Facial Plastic and Reconstructive Surgery

Facial paralysis clinical trial

Dates: 9/2017 to 7/2018

Title: Facial electrical stimulation to promote recovery in patients with facial paralysis from Bell's palsy (IRB 16901)

Source: Medical Research Foundation of Oregon 

Description: A randomized placebo controlled trial to compare the effectiveness of electric stimulation of the face in recovery of patients with poor prognosis for recovery from Bell's palsy.
Patients with complete paralysis and over 60 years of age are eligible to participate.
Electric stimulation is done at home with the equipment we provide.  

Role: Dr. Myriam Loyo. Principal investigator 

If you are interested in finding more about this study please call 503 494-5678 or email .

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