Clinical Trials

he Harold Schnitzer Diabetes Health Center Research Department is committed to promoting and conducting excellent clinical research. Our goal is to enhance the quality of life of those living with or affected by diabetes.

Our efforts to find a cure for diabetes, and to improve life for people with this condition, are made possible by volunteers who participate in research studies. When you volunteer, you help us answer important questions about diabetes.

If you would like to be considered as a potential volunteer for our research studies, please call 503-494-4704, complete our Online Application Form for more information.

Current Research:

T1D: Dexcom CGM Exercise Study

 continous glucose monitoring

We are studying exercise & the new Dexcom Continuous Glucose Monitoring (CGM) system.

The purpose of this study is to test a new Dexcom CGM and to determine if weekly insulin dose changes by the study investigator will improve managing blood sugar in people living with type one diabetes and exercising.You will use a mobile app to track your physical activity and meal data while at home. Meal tracking will include before &after meal images. You also will be given short &long acting insulin pens. You will be compensated up to $500 for participating.

You may be eligible if you:

  • Have type 1 diabetes
  • Are between the ages of 18 to 50
  • Are using multiple daily insulin injections
  • Physically able to perform exercise for 30 minutes ofexercise
What is involved?
  • Six visits to OHSU, each visit is 2.5 hours
  • Study is for 28 days, you'll wear a Dexcom G5,Dexcom G6 and a Fitbit Watch
  • Exercise and you'll receive an insulin pen to track data
For more information, please contact: Debbie Branigan 503-418-9070 or
IRB# 18023

T1D: Closed-loop Study

Enso Circle

You may be able to participate in an artificial pancreas study involving the use of an investigational, stable form of glucagon. The automated system involves the use of a Dexcom G6 glucose sensor, the Omnipod insulin pump and a computer program that determines rates of insulin and glucagon to deliver. Participants will be compensated up to $600 for participating.

You may be eligible if you:

  • Have type 1 diabetes
  • Between the ages of 21 to 50
  • Currently use an insulin pump
  • Ability to exercise for up to 45 minutes

What is involved?

  • 2.5 hour screening visit
  • 1 hour training visit
  • Exercise for 76 hours, which will be broken down into time within clinic and at home
  • Use of the Omnipod and Dexcom G6

For more information, please contact: Debbie Branigan 503-418-9070 or  

IRB# 17225

Evaluating the dynamics of insulin and non-insulin mediated effects on glucose during aerobic exercise in subjects with type 1 diabetes

Currently recruiting patients for this study? Yes

Study started on: 6/16/2017

Principal Investigators: Joseph El Youssef, MD MCR and Peter Jacobs PhD

Co-Investigators: Jessica Castle, MD

Kathy Hanavan RN MSN ANP-BC

Leah Wilson MD

You may qualify to participate if you:

  • Between ages 18 and 45
  • Diagnosed with type 1 diabetes for at least 1 year
  • Physically able to perform exercise for 45 minutes
  • Have a hemoglobin A1c less than 10%

What is involved?

  • 2-hour screening visit
  • 10-hour study visits with 45 minutes of aerobic exercise during each visit
  • 3 short follow-up phone calls after each study visit

Is compensation provided?

$150 for each of three visits for a maximum of $450.

To learn more about participating in this study contact: Debbie Branigan or call 503-494-4739.