Division Research

Division research

Our research programs address fundamental questions related to kidney function in health and disease. We employ a variety of experimental model systems ranging from yeast to humans. Our basic science faculty use a wide array of techniques within molecular biology, genetics, biochemistry, and microscopy to study the physiology and biology of the kidney at the cellular and organism level. Our clinical research faculty utilize varying epidemiologic and clinical research techniques to strengthen our knowledge of kidney disease. As a division, we aim to transform our findings into the improved treatment of renal diseases in collaboration with the Oregon Clinical and Translational Research Institute (OCTRI).

Research Projects

  • Interactions between diet, genes, and aldosterone in causing and treating high blood pressure (Ellison Lab)
  • Causes and treatment of diuretic resistance and kidney tubule remodeling (Ellison Lab)
  • Molecular regulation of sodium and potassium homeostasis (McCormick Lab)
  • Pathologic mechanisms of hypertensive and diabetic kidney disease (Gurley Lab)
  • Kidney disease and hypertension in older adults (Jessica Weiss)
  • Glomerulonephritis clinical outcomes (Rupali Avasare)
  • Genetic factors in systemic water balance and clinical disorders of water and electrolyte balance (Cohen Lab)
  • Off-target effects of anti-proteinuric therapy (Cohen Lab)
  • Pricing and availability of pharmaceuticals (Cohen Lab)
  • Million Veteran Program and All of Us Research Programs on genotype-phenotype investigations (Cohen Lab)
  • Cytomegalovirus exposure, transplant allocation, and outcomes in deceased donor kidney transplantation (Joseph Lockridge)
  • Immunosuppression and rejection rates in African American kidney transplant recipients  (Joseph Lockridge)
  • Streamlining care for thrombosed vascular access (Raghav Wusirika)
  • Estimating GFR in kidney donors pre- and post-donation (Raghav Wusirika)
  • Quality improvement in dialysis outcomes (Pavan Chopra)
  • Pathologic mechanisms of acute cardiorenal syndromes (Michael Hutchens, Anesthesiology)

The CLSB (Collaborative Life Sciences Building) supports many of our basic science researchers and is located in the growing OHSU South Waterfront campus with a beautiful backdrop of the Willamette River.