OHSU Department of Family Medicine

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Study finds breast biopsies may need second look

A study of overinterpretation and underinterpretation of breast biopsies by a sampling of US pathologists has revealed a need for second opinions in certain cases, according to recent article in JAMA.

Family Medicine Researcher  Patty Carney, PhD, was a co-author of Diagnostic Concordance Among Pathologists Interpreting Breast Biopsy Specimens, in the March 17 edition of JAMA. The study found that patients whose biopsies yielded diagnoses like atypia or ductal carcinoma in situ (DCIS) may want to get a second opinion to confirm the diagnosis, as treatment that follows is different based on which type of lesion is present. Both atypia and DCIS breast lesions are associated with higher malignancy risks, and misclassifying these lesions into the wrong categories can lead to either overtreatment or undertreatment.

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