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Chemical Biology and Physiology Summer Undergraduate Research Program (CBP-SURP)
We are excited to announce the 3rd annual Chemical Biology and Physiology Summer Undergraduate Research Program (CBP-SURP). CBP-SURP is a 9-week program designed to provide undergraduates research opportunities at the interface of chemistry, biology and physiology in the health sciences. A major goal of this program is to engage students in state-of the-art techniques in chemical biology, and how strategies in chemical biology can be used to interrogate cell signaling, protein function, and identify potential therapeutic targets.Click here for more information on applying.
Highlighted publication Valiyaveetil lab lab"Main-chain mutagenesis reveals intrahelical coupling in an ion channel voltage-sensor"
Membrane proteins catalyze the passage of information across biological membranes. Central to this function is their ability to undergo conformational changes in response to physiological stimuli. Backbone hydrogen bonds have long been proposed to play an important role in these conformational changes but, until now, technical challenges have prevented their investigation. In this study, the Valiyaveetil group (in collaboration with the Ahern group at U of Iowa) used advanced chemical biology approaches to investigate the role of backbone hydrogen bonds in the voltage sensing transmembrane helix of a eukaryotic potassium channel. The study provides key insights into the physiologically important process of voltage gating in ion channels and establishes a methodology for probing backbone hydrogen bonds, which opens new possibilities for investigating membrane proteins.
Dr. Cohen receives ICBS Young Chemical Biologist Award
Dr. Kelly receives 2018 BIP award
- 02/12/2019 Main-chain mutagenesis reveals intrahelical coupling in an ion channel voltage-sensor
- 11/30/2018 Lights on the endocannabinoid system: Catching cellular membranes in action
- 11/08/2018 Two Physiology and Pharmacology students named as 2018 ARCS Scholars
- 10/11/2018 Research shows a single dose of cocaine irreversibly alters brain
- 09/27/2018 Michael Cohen, Ph.D. receives ICBS Young Chemical Biologist Awards
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