Recent Publications

Chang H, Han J, Borowsky A, Loss L, Gray JW, Spellman PT, Parvin B. Invariant delineation of nuclear architecture in glioblastoma multiforme for clinical and molecular association. IEEE Trans Med Imaging. 2013 Apr;32(4):670-82. PMID: 23221815 [PubMed - in process]

Shou S, Carlson HL, Perez WD, Stadler HS. HOXA13 regulates Aldh1a2 expression in the autopod to facilitate interdigital programmed cell death. Dev Dyn. 2013 Apr 2;. [Epub ahead of print] PMID: 23553814 [PubMed - as supplied by publisher] 

Kasiviswanathan R, Minko IG, Lloyd RS, Copeland WC. Translesion synthesis past acrolein-derived DNA adducts by human mitochondrial DNA polymerase γ. J Biol Chem. 2013 Mar 30;. [Epub ahead of print] PMID: 23543747 [PubMed - as supplied by publisher]

Freeman KA, Eagle R, Merkens LS, Sikora D, Pettit-Kekel K, Nguyen-Driver M, Steiner RD. Challenging behavior in smith-lemli-opitz syndrome: initial test of biobehavioral influences. Cogn Behav Neurol. 2013 Mar;26(1):23-9.     PMID: 23538569 [PubMed - in process]

Owens KM, Quinonez SC, Thomas PE, Keegan CE, Lefebvre N, Roulston D, Larsen CA, Stadler HS, Innis JW.  Analysis of de novo HOXA13 polyalanine expansions supports replication slippage without repair in their generation. Am J Med Genet A. 2013 Mar 26;. [Epub ahead of print] PMID: 23532960 [PubMed - as supplied by publisher]

Goldman JG, Eichenseer SR, Berry-Kravis E, Zimnowodzki S, Gregory A, Hogarth P, Hayflick SJ. Clinical features of neurodegeneration with brain iron accumulation due to a C19orf12 gene mutation. Mov Disord. 2013 Mar 13;. [Epub ahead of print] PMID: 23494994 [PubMed - as supplied by publisher]

Tagami T, Okuyama M, Nakai H, Kim YM, Mori H, Taguchi K, Svensson B, Kimura A. Key aromatic residues at subsites +2 and +3 of glycoside hydrolase family 31 α-glucosidase contribute to recognition of long-chain substrates. Biochim Biophys Acta. 2013 Jan;1834(1):329-35. PMID: 23457711 [PubMed - indexed for MEDLINE]

Huch M, Dorrell C, Boj SF, van Es JH, Li VS, van de Wetering M, Sato T, Hamer K, Sasaki N, Finegold MJ, Haft A, Vries RG, Grompe M, Clevers H. In vitro expansion of single Lgr5(+) liver stem cells induced by Wnt-driven regeneration. Nature. 2013 Jan 27;. PMID: 23354049

Donley N, Thayer MJ. DNA replication timing, genome stability and cancer: Late and/or delayed DNA replication timing is associated with increased genomic instability. Semin Cancer Biol. 2013 Jan 14;. PMID: 23327985  

Ketkar A, Zafar MK, Maddukuri L, Yamanaka K, Banerjee S, Egli M, Choi JY, Lloyd RS, Eoff RL. Leukotriene Biosynthesis Inhibitor MK886 Impedes DNA Polymerase Activity. Chem Res Toxicol. 2013 Jan 31;. PMID: 23305233

Kurinna S, Stratton SA, Coban Z, Schumacher JM, Grompe M, Duncan AW, Barton MC. p53 regulates a mitotic transcription program and determines ploidy in normal mouse liver. Hepatology. 2013 Jan 8;. PMID: 23300120

Verhaak RG, Tamayo P, Yang JY, Hubbard D, Zhang H, Creighton CJ, Fereday S, Lawrence M, Carter SL, Mermel CH, Kostic AD, Etemadmoghadam D, Saksena G, Cibulskis K, Duraisamy S, Levanon K, Sougnez C, Tsherniak A, Gomez S, Onofrio R, Gabriel S, Chin L, Zhang N, Spellman PT, Zhang Y, Akbani R, Hoadley KA, Kahn A, Köbel M, Huntsman D, Soslow RA, Defazio A, Birrer MJ, Gray JW, Weinstein JN, Bowtell DD, Drapkin R, Mesirov JP, Getz G, Levine DA, Meyerson M. Prognostically relevant gene signatures of high-grade serous ovarian carcinoma. J Clin Invest. 2013 Jan 2;123(1):517-25. PMID: 23257362

Wang Z, Liu Y, Takahashi M, Van Hook K, Kampa-Schittenhelm KM, Sheppard BC, Sears RC, Stork PJ, Lopez CD. N terminus of ASPP2 binds to Ras and enhances Ras/Raf/MEK/ERK activation to promote oncogene-induced senescence. Proc Natl Acad Sci U S A. 2013 Jan 2;110(1):312-7. PMID: 23248303

Cox TM, Amato D, Hollak CE, Luzy C, Silkey M, Giorgino R, Steiner RD. Evaluation of miglustat as maintenance therapy after enzyme therapy in adults with stable type 1 Gaucher disease: a prospective, open-label non-inferiority study. Orphanet J Rare Dis. 2012 Dec 27;7(1):102. [Epub ahead of print] PMID: 23270487

Hogarth P, Gregory A, Kruer MC, Sanford L, Wagoner W, Natowicz MR, Egel RT, Subramony SH, Goldman JG, Berry-Kravis E, Foulds NC, Hammans SR, Desguerre I, Rodriguez D, Wilson C, Diedrich A, Green S, Tran H, Reese L, Woltjer RL, Hayflick SJ. New NBIA subtype: Genetic, clinical, pathologic, and radiographic features of MPAN. Neurology. 2012 Dec 26;. [Epub ahead of print] PMID: 23269600

Smith L, Thayer M. Chromosome Replicating Timing Combined with Fluorescent In situ Hybridization. J Vis Exp. 2012 Dec 10;(70). PMID: 23271586

Chang H, Han J, Spellman PT, Parvin B. Multireference level set for the characterization of nuclear morphology in glioblastoma multiforme. IEEE Trans Biomed Eng. 2012 Dec;5 9(12):3460-7. PMID: 22987497

Polejaeva I, Mitalipov S. Stem cell potency and the ability to contribute to chimeric animals. Reproduction. 2012 Dec 5;. [Epub ahead of print] PMID: 23221011

Sampath H, Vartanian V, Rollins MR, Sakumi K, Nakabeppu Y, Lloyd RS. 8-Oxoguanine DNA Glycosylase (OGG1) Deficiency Increases Susceptibility to Obesity and Metabolic Dysfunction. PLoS One. 2012;7(12):e51697. PMID: 23284747

Ordinario E, Han HJ, Furuta S, Heiser LM, Jakkula LR, Rodier F, Spellman PT, Campisi J, Gray JW, Bissell MJ, Kohwi Y, Kohwi-Shigematsu T. ATM Suppresses SATB1-Induced Malignant Progression in Breast Epithelial Cells. PLoS One. 2012;7(12):e51786. PMID: 23251624

Kulesz-Martin MF, Lagowski J, Olson S, Wortham A, West T, Thomas G, Ryan C, Tyner JW. A molecular case report: Functional assay of tyrosine kinase inhibitors in cells from a patient's primary renal cell carcinoma. Cancer Biol Ther. 2012 Nov 28;14(2). [Epub ahead of print] PMID: 23192268

Agarwal P, Hogarth P, Hayflick S, Macleod P, Kuriakose R, McKenzie J, Heffernan N, Dinelle K, Sossi V, Stoessl AJ. Imaging striatal dopaminergic function in Phospholipase A2 Group VI-related parkinsonism. Mov Disord. 2012 Nov;27(13):1698-9. PMID: 23192926

Link JM, Ota S, Zhou ZQ, Daniel CJ, Sears RC, Hurlin PJ. A critical role for Mnt in Myc-driven T-cell proliferation and oncogenesis. Proc Natl Acad Sci U S A. 2012 Nov 27;109(48):19685-90. PMID: 23150551

Haack TB, Hogarth P, Kruer MC, Gregory A, Wieland T, Schwarzmayr T, Graf E, Sanford L, Meyer E, Kara E, Cuno SM, Harik SI, Dandu VH, Nardocci N, Zorzi G, Dunaway T, Tarnopolsky M, Skinner S, Frucht S, Hanspal E, Schrander-Stumpel C, Héron D, Mignot C, Garavaglia B, Bhatia K, Hardy J, Strom TM, Boddaert N, Houlden HH, Kurian MA, Meitinger T, Prokisch H, Hayflick SJ. Exome Sequencing Reveals De Novo WDR45 Mutations Causing a Phenotypically Distinct, X-Linked Dominant Form of NBIA. Am J Hum Genet. 2012 Nov 20;. [Epub ahead of print] PMID: 23176820