Publications

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MicroRNA-451a regulates colorectal cancer proliferation in response to radiation.
Ruhl R, Rana S, Kelley K, Espinosa-Diez C, Hudson C, Lanciault C, Thomas CR, Liana Tsikitis V, Anand S. 2018. BMC Cancer 18: 517

MicroRNA regulation of the MRN complex impacts DNA damage, cellular senescence, and angiogenic signaling.
Espinosa-Diez C, Wilson R, Chatterjee N, Hudson C, Ruhl R, Hipfinger C, Helms E, Khan OF, Anderson DG, Anand S. 2018. Cell Death & Disease 9: 632

Colorectal Cancer Liver Metastasis: Evolving Paradigms and Future Directions.
Zarour LR, Anand S, Billingsley KG, Bisson WH, Cercek A, Clarke MF, Coussens LM, Gast CE, Geltzeiler CB, Hansen L, Kelley KA, Lopez CD, Rana SR, Ruhl R, Tsikitis VL, Vaccaro GM, Wong MH, Mayo SC. 2017. Cell Mol Gastroenterol Hepatol 3: 163-73

Understanding and Resetting Radiation Sensitivity in Rectal Cancer.
Kelley KA, Ruhl RA, Rana SR, Dewey E, Espinosa C, Thomas CRJ, Martindale RG, Anand S, Tsikitis VL. 2017. Annals of Surgery 266: 610-6

MicroRNAs in Cancer: challenges and opportunities in early detection, disease monitoring, and therapeutic agents.
Chatterjee N, Rana S, Espinosa-Diez C, Anand S. 2017.  Curr Pathobiol Rep 5: 35-42

MicroRNA regulation of endothelial TREX1 reprograms the tumour microenvironment.
Wilson R, Espinosa-Diez C, Kanner N, Chatterjee N, Ruhl R, Hipfinger C, Advani SJ, Li J, Khan OF, Franovic A, Weis SM, Kumar S, Coussens LM, Anderson DG, Chen CC, Cheresh DA, Anand S. 2016. Nat Commun 7: 13597

Kinase-independent role for CRAF-driving tumour radioresistance via CHK2.
Advani SJ, Camargo MF, Seguin L, Mielgo A, Anand S, Hicks AM, Aguilera J, Franovic A, Weis SM, Cheresh DA. 2015. Nat Commun 6: 8154

An integrin beta3-KRAS-RalB complex drives tumour stemness and resistance to EGFR inhibition.
Seguin L, Kato S, Franovic A, Camargo MF, Lesperance J, Elliott KC, Yebra M, Mielgo A, Lowy AM, Husain H, Cascone T, Diao L, Wang J, Wistuba II, Heymach JV, Lippman SM, Desgrosellier JS, Anand S et al. Nature Cell Biology. 2014 May;16(5):457-68. PubMed PMID: 24747441.

Manipulating microRNAs to regulate macrophage polarization in gliomas.
Anand S, Coussens LM. 2014. J Natl Cancer Inst 106.

Inhibiting the Ras pathway prevents neovascularization by repressing endothelial cell sprouting
Westenskow, P.D., Kurihara, T., Aguilar, E., Scheppke, E.L., Moreno, S.K., Marchetti, V., Michael, I.P., Anand, S., Nagy, A., Cheresh, D.A., and Friedlander, M. 2013. J Clin Invest. 123(11):4900–4908. 

A brief primer on microRNAs and their roles in angiogenesis.
Anand S. 2013. Vasc Cell 5: 2

Expression of anti-HVEM single chain antibody on tumor cells induces tumor-specific immunity with long-term memory
Park J-J*, Anand S*, Zhao Y*, Matsumura Y, Sakoda Y, Kuramasu A, Strome SE, Chen L, Tamada K. Cancer Immunology & Immunotherapy. 2012. 61(2): 203-14.* Equal contribution.

EGFR-mediated carcinoma cell metastasis mediated by integrin alphavbeta5 depends on activation of c-Src and cleavage of MUC1.
Lau SK, Shields DJ, Murphy EA, Desgrosellier JS, Anand S, Huang M, Kato S, Lim ST, Weis SM, Stupack DG, Schlaepfer DD, Cheresh DA. 2012. PLoS One 7: e36753

EGFR-dependent pancreatic carcinoma cell metastasis via Rap1 activation
Huang M, Anand S, Murphy EA, Desgrosellier JS, Stupack DG, Shattil SJ, Schlaepfer DD, Cheresh DA. Oncogene. 2011. 31:2783-2793.

Regulation of Hypoxia-Inducible Factor-1α and Erythropoiesis by Herpesvirus Entry Mediator
Sakoda Y*, Anand S*, Zhao Y*, Park J-J, Liu Y, Kuramasu A, van Rooijen N, Strome SE, Hancock WW, Chen L, and Tamada K. Journal of Clinical Investigation. 2011. 121(12): 4810-9 * Equal Contribution. 

A MEK-independent role for CRAF in mitosis and tumor progression
Mielgo A, Seguin L, Huang M, Camargo MF, Anand S, Franovic A, Weis SM, Advani SJ, Murphy EA, Cheresh DA. Nature Medicine 2011. 17(12): 1641-5.

MicroRNA-mediated regulation of the angiogenic switch.
Anand S, Cheresh DA. 2011. Curr Opin Hematol 18: 171-6

Emerging Role of Micro-RNAs in the Regulation of Angiogenesis.
Anand S, Cheresh DA. 2011. Genes Cancer 2: 1134-8

B7-H1/CD80 interaction is required for the induction and maintenance of peripheral T-cell tolerance.
Park JJ, Omiya R, Matsumura Y, Sakoda Y, Kuramasu A, Augustine MM, Yao S, Tsushima F, Narazaki H, Anand S, Liu Y, Strome SE, Chen L, Tamada K. 2010. Blood 116: 1291-8

Disruption of angiogenesis and tumor growth with an orally active drug that stabilizes the inactive state of PDGFRbeta/B-RAF
Murphy EA, Shields DJ, Stoletov K, Dneprovskaia E, McElroy M, Greenberg JI, Lindquist J, Acevedo LM, Anand S, Majeti BK, et al. Proceedings of the National Academy of Sciences of U S A 2010, 107:4299-4304. 

MicroRNA-132-mediated loss of p120RasGAP activates the endothelium to facilitate pathological angiogenesis
Anand S, Majeti BK, Acevedo LM, Murphy EA, Mukthavaram R, Scheppke L, Huang M, Shields DJ, Lindquist JN, Lapinski PE, et al. Nature Medicine 2010, 16:909-914. 

B7-H4-deficient mice display augmented neutrophil-mediated innate immunity.
Zhu G, Augustine MM, Azuma T, Luo L, Yao S, Anand S, Rietz AC, Huang J, Xu H, Flies AS, Flies SJ, Tamada K, Colonna M, van Deursen JM, Chen L. 2009. Blood 113: 1759-67

Selective targeting of the LIGHT-HVEM costimulatory system for the treatment of graft-versus-host disease.
Xu Y, Flies AS, Flies DB, Zhu G, Anand S, Flies SJ, Xu H, Anders RA, Hancock WW, Chen L, Tamada K. 2007. Blood 109: 4097-104

Essential role of TNF family molecule LIGHT as a cytokine in the pathogenesis of hepatitis
Anand S, Wang P, Yoshimura K, Choi IH, Hilliard A, Chen YH, Wang CR, Schulick R, Flies AS, Flies DB, et al. Journal of Clinical Investigation 2006, 116:1045-1051.

Control of autoimmune diseases by the B7-CD28 family molecules.
Anand S, Chen L. 2004. Curr Pharm Des 10: 121-8