Summer 2019 internship announced!The National Cancer Institute (NCI) Summer Internships for 2019 have been announced! One of the sixteen internship positions is located here as OCSSB within the M2CH. Learn more and apply at the NCI Systems Biology and Physical Science Summer Research Program web page. Applications are due February 15, 2019.
The Associate Department Administrator is responsible for the oversight and management of the financial, operational, human resources, and administrative functions of the OCSSB under the leadership of the Senior Department Administrator and the Center Director. Responsibilities include but not limited to: oversight of the financial management of operational, startup, foundation and contract funding as well as a shared service center; grants management including a large portfolio of subcontractors and subprojects; personnel recruitment and management; and oversight of space planning; facilities; procurement; inventory and equipment.
The Knight Cancer Institute and OHSU Center for Spatial Systems Biology (OCSSB) invite applications for a faculty position at the level of assistant or associate professor. We seek to recruit a faculty member to develop an independent research program aimed at elucidation of the structure and function of cancer related proteins and protein complexes using single particle cryoEM, cryoEM tomography, multicolor superresolution fluorescence microscopy and/or correlative light and electron microscopy. Participation in graduate education programs in the Department of Biomedical Engineering and/or the Program in Molecular and Cell Biology is also expected.
The OCSSB and Department of Biomedical Engineering have an open postdoctoral researcher position in the Korkola Lab. The fellow will conduct research on the microenvironment, working collaboratively with researchers at the University of Cambridge to investigate the role that senescent cells play on tumor initiation and progression. Projects in the Korkola Lab utilize skills in the areas of cell and molecular biology, molecular imaging, protein engineering, and biochemistry.
This position is a member of a research team under the supervision of Professor Joe Gray in the Biomedical Engineering Department and the OHSU Center for Spatial Systems Biomedicine (OCSSB). Talented, motivated and highly interactive bioinformatics Postdoctoral Scholar to participate in the automatic segmentation and feature extraction of 3-dimensional light and electron microscopy datasets to identify changes in cellular signaling networks that accompany cancer progression and drug resistance. A strong background in machine/deep learning and programming is desired. Some design of experiments and procedures will be required along with responsibilities for many phases of a research project. The successful applicant will be responsible for analyzing high-throughput molecular profiling data including sequencing and functional assays. Postdoctoral Scholar to serve in a Computational Biologist role.
View details and apply online (IRC77030)
The OHSU Center for Spatial Systems Biomedicine and the Program in Chemical Biology has an open postdoctoral researcher position in the Beatty Lab. The fellow will conduct research at the interface of chemistry and biology, working collaboratively to develop and optimize novel fluorescent tags for imaging cellular proteins. Projects in the Beatty Lab utilize skills in the areas of synthetic chemistry, molecular imaging, cell biology, protein engineering, bioconjugation reactions (e.g., “click chemistry”), biochemistry, and molecular biology. Will develop new genetically encoded protein tags for tracking proteins by confocal fluorescence microscopy, super-resolution microscopy, and by electron microscopy (EM). Will also be responsible for designing and validating novel protein tags. A long-term goal of this project will be to elucidate multi-protein interactions by high resolution microscopy.
View details and apply online (IRC77031)
Research Assistant/Associate Positions
The Research Associate - Imaging Specialist will work to provide support for the biological imaging activities for the Nan Lab, and will be further trained on single-molecule and superresolution imaging with emphasis on microscope operation, maintenance, and data processing.
The Research Assistant 2 - Cryo-Electron Microscopy (PNCC) will work to provide support to the team by conducting specimen preparation and experiments using appropriate techniques, and providing research support and training to visiting Scientists at Pacific Northwest CryoEM Center (PNCC), a joint collaboration between Oregon Health and Science University (OHSU) and the Pacific Northwest National Laboratory (PNNL). The PNCC is a national facility serving and training researchers in the entire US. The Center, scheduled to open in October 2018 will include two 300 KeV cryo Transmission EMs (TEM), two 200 KeV cryoTEMs and a cryo FIB Scanning EM. The cryoTEMs will be outfitted with Falcon III, post GIF K3 and volta phase plate technologies. This center will also have all standard equipment for sample preparation and purification. This role is ideal for those with limited laboratory experience who are looking to develop and refine their skills in this exciting area of research. Junior and senior roles available for those at all skill levels. We will gladly review your resume and cover letter detailing your experiences working in a similar capacity.
Become a member of a research engineering team under the supervision of Principal Investigator Dr. Tania Vu, an Associate Professor in the Biomedical Engineering Department and member of the Knight Cancer Institute. Participate in efforts to develop and apply new microscope imaging technology for precision oncology.
The Research Assistant will provide research and technical support to understand dynamic heterogeneous responses of cells after treatment with various perturbations. The duties are expected to be carried out with minimal oversight. This position will involve interaction in collaborative projects with teams composed of experimental and computational biologists.
Talented, motivated and highly interactive bioinformatics Senior Research Assistant to participate in the annotation and feature extraction of 3-dimensional light and electron microscopy datasets to identify changes in cellular signaling networks that accompany cancer progression and drug resistance. A strong background in computational biology or informatics is desired. Some design of experiments and procedures will be required along with responsibilities for many phases of a research project. The successful applicant will be responsible for analyzing high-throughput molecular profiling data including sequencing and functional assays. Senior Research Assistant to serve in a Computational Biologist role. Advanced skills to be utilized with work on annotating electron microscope images to make them three dimensional. This requires an advance understanding of both electron microscopy and the computational tools needed to turn these images into data that can be interpreted by scientific audiences. Knowledge of machine learning approaches highly desirable. B.S. required; M.S. or Ph.D. preferred.
View details and apply online (IRC77029)
We have an immediate opening for a talented, motivated and highly interactive research assistant to participate in the annotation and feature extraction of 3-dimensional (3D) light and electron microscopy (EM) datasets to identify changes in cellular signaling networks that accompany cancer progression and drug resistance. Some design of experiences and procedures will be required. They will participate in research efforts focusing on the use of data generated with cutting-edge high resolution microscopy techniques which explore the complex tumor state found in clinical samples. They will be working closely with biologists, microscopy experts, and computer scientists to identify features of interest within large volume 3D-EM data using both commercially available software and custom built software packages. They will use tools that range from manual feature extraction to automated segmentation to help enable the large-scale image analysis of volume EM data.
View details and apply online (IRC77027)
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