Technology Pipeline
OHSU Technology Transfer currently manages hundreds of active licenses. The Technology Pipeline below illustrates a number of licensed OHSU technologies currently in product development or on the market.
Therapeutics Pipeline
| Pre-Clinical | Clinical | Market | |
|---|---|---|---|
| Contrave® | ✅ | ✅ | ✅ |
| Gleevec® for treatment of gastrointestinal stromal tumor | ✅ | ✅ | ✅ |
| Hydrovax™ | ✅ | ✅ | |
| Multipotent progenitor cells to treat immune dysfunction | ✅ | ✅ | |
| Poly-ICLC for treatment of cytotoxic insults | ✅ | ✅ | |
| RTL1000 | ✅ | ✅ | |
| Sobetirome for treatment of neurodegenerative disease | ✅ | ✅ | |
| Sodium thiosulfate for chemoprotection | ✅ | ✅ | |
| AAV vaccine vector for gene therapy | ✅ | ||
| Anti-inflammatory compound | ✅ | ||
| Aptamer-SiRNA Chimera for treatment of psoriasis | ✅ | ||
| Aryl piperidinequinazolinones for treatment of drug addiction | ✅ | ||
| CMV vaccine vector for disease treatment | ✅ | ||
| Dengue virus vaccine | ✅ | ||
| DNA repair enzymes for treatment of skin cancer | ✅ | ||
| Endochin-like quinolones for treatment of parasitic infections | ✅ | ||
| Fertility method | ✅ | ||
| Gene correction | ✅ | ||
| Immunotherapeutic treatment using nanoparticle platform | ✅ | ||
| Inhibitors of cancer-mediated bone destruction | ✅ | ||
| Inhibitors of PARPs that catalyze mono-ADP-ribosylation | ✅ | ||
| Inhibitors of the mitochondrial permeability transition pore | ✅ | ||
| Leucine zipper-TRAIL fusion constructs as anti-tumor agents | ✅ | ||
| Melatonin to adjust sleep cycle | ✅ | ||
| Method to minimize residual disease and relapse in cancer | ✅ | ||
| Nanoparticle platform for siRNA delivery to solid tumors | ✅ | ||
| Napthphamides for treatment of cancer | ✅ | ||
| Novel antibodies for detection and treatment of cancer | ✅ | ||
| Peptide for hearing | ✅ | ||
| Peptide for sepsis | ✅ | ||
| Piperine vitiligo and melanoma | ✅ | ||
| Protein for skin | ✅ | ||
| Pyrroloquinazolines for treatment of breast cancer | ✅ | ||
| Quinolines for treament of parasitic infections | ✅ | ||
| siRNA for treatment of dengue virus | ✅ | ||
| Small molecule agonist of STING pathway | ✅ | ||
| SOX9 Protein for cartilage regeneration | ✅ | ||
| Therapeutic co-delivery using nanoparticle platform | ✅ | ||
| Use of microRNA inhibitors to enhance radiotherapy efficacy | ✅ | ||
| Vaccine for treatment of tuberculosis | ✅ |
Diagnostic Pipeline
| Pre-Clinical | Clinical | Market | |
|---|---|---|---|
| Questionnaire for facial pain | ✅ | ✅ | ✅ |
| Visual field modeling and analysis | ✅ | ✅ | |
| Adipose-specific fluorescent dyes for in vivo imaging | ✅ | ||
| Automated detection of melanoma | ✅ | ||
| Automatic non-invasive assessment of skin | ✅ | ||
| Biomarkers identifying treatments in Acute Myeloid Leukemia | ✅ | ||
| Biomarkers predicting venetoclax sensitivity | ✅ | ||
| Cell fusions for cancer prognosis and diagnosis | ✅ | ||
| Combinations of targeted agents for hematologic malignancies | ✅ | ||
| Diabetes algorithm | ✅ | ||
| Dye-enhanced multimodal confocal imaging | ✅ | ||
| Formulation strategies for administration of nerve-specific dyes | ✅ | ||
| Labor prediction | ✅ | ||
| Mass transcription factor analysis | ✅ | ||
| Novel fluorescent dyes for in vivo nerve-specific imaging | ✅ | ||
| Optical fiber spectroscopy device | ✅ | ||
| RNA biomarkers for predicting radiotherapy effectiveness | ✅ | ||
| Second generation dyes for in vivo nerve-specific imaging | ✅ | ||
| Sirolimus-eluting cuff | ✅ |
Device Pipeline
| Pre-Clinical | Clinical | Market | |
|---|---|---|---|
| Endoscopy reporting | ✅ | ✅ | ✅ |
| Inner ear test | ✅ | ✅ | ✅ |
| OCT angiography | ✅ | ✅ | ✅ |
| Smartphone diagnostic | ✅ | ✅ | ✅ |
| Stroke rehab system | ✅ | ✅ | ✅ |
| Breast cancer MRI | ✅ | ✅ | |
| Healthcare software | ✅ | ✅ | |
| OCT angiography | ✅ | ✅ | |
| Speech recognition software for autism diagnosis | ✅ | ✅ | |
| Apnea prevention device | ✅ | ||
| Automated detection and counting of biomolecules using nanoparticles | ✅ | ||
| Bulk motion subtraction in OCT-A | ✅ | ||
| Cardiovascular stent | ✅ | ||
| Cardiovascular stent delivery | ✅ | ||
| Cardiovascular valve | ✅ | ||
| CNV detection for OCT angiography | ✅ | ||
| Deep learning vascular area on OCT -A | ✅ | ||
| Method for OCT angiography | ✅ | ||
| MRI motion artifact reduction | ✅ | ||
| Prostate biopsy device | ✅ | ||
| QD molecular assay for personalized oncoprotein detection in leukemia | ✅ | ||
| Registration, montage for wide-field OCT-A | ✅ | ||
| Reflectance-based projection-resolved OCT-A | ✅ | ||
| Shadowgraphic flow projection removal | ✅ | ||
| Smartphone far-point refraction | ✅ | ||
| Software for deep-learning inference of histopathology biomarkers | ✅ | ||
| Ultrasensitive detection of proteins in cells | ✅ |
Non-Clinical Pipeline
| Pre-Market | Market | |
|---|---|---|
| Anonymized prostate MRI image sets | ✅ | ✅ |
| Antibody against (hSERT) 8B6 | ✅ | ✅ |
| Antibody for human Va7.2 T cell receptor | ✅ | ✅ |
| Antibody for sodium channel | ✅ | ✅ |
| Antibody form HICO-3B3 | ✅ | ✅ |
| Bacterial artificial chromosome clone | ✅ | ✅ |
| BaF3 cell lines | ✅ | ✅ |
| Balance evaluation systems test: BESTest | ✅ | ✅ |
| BB19 cell Line | ✅ | ✅ |
| CBP expression vector | ✅ | ✅ |
| Cell lines expressing receptor SSTR1 | ✅ | ✅ |
| Community ability scale | ✅ | ✅ |
| Continuous monitoring of objective quality of life functions | ✅ | ✅ |
| Copyright tagline | ✅ | ✅ |
| CORI endoscopy procedure software | ✅ | ✅ |
| CORPORA | ✅ | ✅ |
| D2 dopamine receptor | ✅ | ✅ |
| Dangerous decibels | ✅ | ✅ |
| Dataset - parkinsonism, chest-mounted sensor | ✅ | ✅ |
| De-identified amyloidosis diagnostic test data | ✅ | ✅ |
| Dermatology curriculum | ✅ | ✅ |
| Full text to speech with OGIResLPC | ✅ | ✅ |
| Furin endoprotease Inhibiting reagents | ✅ | ✅ |
| Health outcomes and care data base | ✅ | ✅ |
| HeLa cell line clones | ✅ | ✅ |
| Human antibody | ✅ | ✅ |
| Human cytomegalovirus strains | ✅ | ✅ |
| Incremental speech recognition for dialog systems | ✅ | ✅ |
| Knock-out mice | ✅ | ✅ |
| MIC1-1C3 antibody | ✅ | ✅ |
| Monoclonal antibody supernatants | ✅ | ✅ |
| Mouse model | ✅ | ✅ |
| Neurology Illustration | ✅ | ✅ |
| OC2-2F3 antibody | ✅ | ✅ |
| OC2-3C7 antibody | ✅ | ✅ |
| Part of speech tagger | ✅ | ✅ |
| Passively cooled, dome-shaped data center | ✅ | ✅ |
| Polyclonal antibodies - tumorigenesis | ✅ | ✅ |
| Python WORLD cocoder | ✅ | ✅ |
| Rabbit polyclonal antibodies against human CMV | ✅ | ✅ |
| Rabbit polyclonal antibody | ✅ | ✅ |
| Real-space refinement of macromolecular structures | ✅ | ✅ |
| ReBEL software | ✅ | ✅ |
| Reduced-dimension data assimilation (RDDA) | ✅ | ✅ |
| SCCM virtual skill station | ✅ | ✅ |
| Solid tissue samples for research purposes | ✅ | ✅ |
| Sound identification tutor | ✅ | ✅ |
| Speech synthesis | ✅ | ✅ |
| Synthetic dark frame computation | ✅ | ✅ |
| The Pacific Northwest anti-Inflammatory reference cookbook | ✅ | ✅ |
| TimeView, a python-based signal viewer application | ✅ | ✅ |
| Tissue samples for research | ✅ | ✅ |
| Transgenic mice | ✅ | ✅ |
| Twiticher mice model | ✅ | ✅ |
| Veteran supportive supervisor training materials | ✅ | ✅ |
| Voice transformation | ✅ | ✅ |
| Antibodies to human gall bladder cells | ✅ | |
| Antibodies to intestinal stem cell populations | ✅ | |
| Antibodies to the human CD46 cytoplasmic tails Cyt1 and Cyt2 | ✅ | |
| Antibody for the isolation of live mouse pancreatic acinar cells | ✅ | |
| Artificial pancreas apps | ✅ | |
| Automatic nuclei segmentation in histopathology images | ✅ | |
| Bone marrow-on-a-chip | ✅ | |
| Diabetes clinical app | ✅ | |
| Multispectral superresolution microscopy | ✅ | |
| Peptide tags for high resolution microscopy | ✅ | |
| Position tracking and mobility assessment system | ✅ | |
| Tinnitus test | ✅ |
* OHSU Technology Transfer pipelines last updated Oct. 28, 2019.