Selected publications

Vartanian KB, Mitchell HD, Stevens SL, Conrad VK, McDermott JE, Stenzel-Poore MP. CpG preconditioning regulates miRNA expression that modulates genomic reprogramming associated with neuroprotection against ischemic injury. J. Cerebral Blood Flow & Metabolism 35: 257-266, 2015. PMC Journal-In Process.

Stevens SL, Vartanian KB, Stenzel-Poore MP. Reprogramming the response to stroke by preconditioning. Stroke 45: 2527-2531, 2014. PMC4240276.

Bahjat FR, Gesuete R, Stenzel-Poore MP. Steps to Translate Preconditioning from Basic Research to the Clinic. Translational Stroke Research 4(1): 89-103, 2013. PMC3595131.

Packard AEB, Leung PY, Vartanian KB, Stevens SL, Bahjat FR, Stenzel-Poore MP. TLR9 bone marrow chimeric mice define a role for cerebral TNF in neuroprotection induced by CpG preconditioning. Journal of Cerebral Blood Flow & Metabolism 32: 2193-2200, 2012. PMC3519417.

Gesuete R, Packard AEB, Vartanian KB, Conrad VK, Stevens SL, Bahjat FR, Yang T, Stenzel-Poore MP. Poly-ICLC preconditioning protects the blood-brain barrier against ischemic injury in vitro through type I Interferon signaling. J. Neurochemistry 123 Suppl 2: 75-85, 2012. PMC3481200.

McDermott JE, Vartanian KB, Mitchell H, Stevens SL, Sanfilippo A, Stenzel-Poore MP. Identification and validation of Ifit1 as an important innate immune bottleneck. PLoS ONE 7(6): e36465, 2012. PMC3380000.

Leung PY, Stevens SL, Packard AEB, Lessov NS, Yang T, Conrad VK, van den Dungen NNAM, Simon RP, Stenzel-Poore MP. TLR7 preconditioning induces robust neuroprotection against stroke by a novel type I interferon-mediated mechanism. Stroke 43: 1383-1389, 2012. PMC3943206.

Packard AEB, Hedges JC, Bahjat FR, Stevens SL, Conlin MJ, Salazar AM, Stenzel-Poore MP. Poly-IC preconditioning protects against cerebral and renal ischemia-reperfusion injury. Journal of Cerebral Blood Flow & Metabolism 32: 242-247, 2012. PMC3272611.

Vartanian KB, Stevens SL, Marsh BJ, Williams-Karnesky R, Lessov NS, Stenzel-Poore MP. LPS preconditioning redirects TLR signaling following stroke: TRIF-IRF3 plays a seminal role in mediating tolerance to ischemic injury. J. Neuroinflammation 8:140, 2011. PMC3217906

Stevens SL, Leung PY, Vartanian KB, Gopalan B, Yang T, Simon RP, Stenzel-Poore MP. Multiple preconditioning paradigms converge on interferon regulatory factor dependent signaling to promote tolerance to ischemic brain injury. J. Neuroscience 31: 8456-8463, 2011. PMC3130521

Bahjat FR, Williams-Karnesky RL, Kohama SG, West GA, Doyle KP, Spector MD, Hobbs TR, Stenzel-Poore MP. Proof of concept: pharmacological preconditioning with a Toll-like receptor agonist protects against cerebrovascular injury in a primate model of stroke. J. Cerebral Blood Flow & Metabolism 31: 1229-42, 2011. PMC3099644

West GA, Golshani KJ, Doyle KP, Lessov NI, Hobbs TR, Kohama SG, Pike MM, Kroenke CD, Grafe MR, Spector MD, Tobar ET, Simon RP, Stenzel-Poore MP.  A new model of cortical stroke in the rhesus macaque.  J. Cerebral Blood Flow & Metabolism, 29(6):1175-86, 2009. PMC2828874.

Stevens SL, Ciesielski T, Marsh BJ, Yang T, Homen D, Lessov N, Simon RP, Stenzel-Poore MP. Toll-like receptor 9: A new target of ischemic preconditioning in the brain. J Cereb Blood Flow Metab, 28:1040-1047, 2008. PMC3037270.