INSPIRE Lab

INSPIRE Lab

Research

Recent grants/awards

  • 2021-2032       HEALthy Brain and Child Development Study (HBCD)
    NIH HEAL Initiative, role: co-PI
  • 2018-2021       A targeted approach to examine the influence of maternal psychological stress on newborn brain outcome
    NIH R00 MH111805, role: PI
  • 2018-2019       Effects of a mindfulness based intervention during pregnancy on maternal inflammation and infant outcomes
    Medical Research Foundation of Oregon, New Investigator Award, role: PI
  • 2016-2023       Environmental influences on child health outcomes (ECHO)
    UG3 OD023349, role: Co-I (PIs: Buss, O’Connor, Wadhwa, Miller, Simhan)
  • 2018-2020       Mechanisms of Action of MBCT-PD: A Pilot Study
    NCCIH R21DA046949, role: co-I (PI: Mackiewicz Seghete)

Selected publications

(* indicates work by a mentored student)

Graham, AM, Doyle, O, Tilden, EL, Sullivan, E, Gustafsson, HC, Marr, M, Allen, M, Mackiewicz Seghete, KL. Effects of maternal psychological stress during pregnancy on offspring brain development: Considering the role of inflammation and potential for preventive intervention. Biological Psychiatry: Cognitive Neuroscience and Neuroimaging. Online ahead of print doi.org/10.1016/j.bpsc.2021.10.012

Gustafsson, H.C., Young, A.S., Doyle, O., Nagel, B., Mackiewicz Seghete, K., Nigg, J.T., Sullivan, E.L., Graham, A.M. (2021). Trajectories of perinatal depressive symptoms in the context of the COVID-19 pandemic. Child Development, 92(5), 749-763.

Ramirez, J.S.B., Graham, A.M., Thompson, J.R., Zhu, J.Y., Sturgeon, D., Bagley, J.L., Thomas, E., Papadakis, S., Perrone, A., Earl, E., Miranda Dominguez, O., Feczko, E., Fombone, E.J., Amaral., D.G., Nigg, J.T., Sullivan, E.L., Fair, D. (in press)., Maternal interleukin-6 is associated with macaque offspring amygdala development and behavior. Cerebral Cortex.

Thomas*, E., Buss, C., Rasmussen, J.M., Entringer, S., Ramirez, J.S.B., Marr, M.,  Rudolph,  M.D., Gilmore, J.H., Styner, M., Wadhwa, P.D., Fair, D.A., & Graham, A.M. (2019). Newborn amygdala connectivity and early emerging fear. Developmental Cognitive Neuroscience. 37, 100604.

Feczko, E., Miranda Dominguez, O., Marr, M., Graham, A.M., Nigg, J.T., & Fair, D.A. (2019). The heterogeneity problem: Approaches to identify psychiatric subtypes. Trends in Cognitive Sciences, 23(7), 584-601.

Graham, A.M., Rasmussen, J.M., Entringer, S., Ward, E.B., Rudolph, M.D., Gilmore, J.H., Styner, M., Wadhwa, P.D., Fair, D.A., & Buss, C. (2019). Maternal Cortisol Concentrations During Pregnancy and Sex Specific Associations with Neonatal Amygdala Connectivity and Emerging Internalizing Behaviors. Biological Psychiatry, 85(2), 172-181.

Rudolph, M.D., Graham, A.M., Feczko, E., Miranda-Dominguez, O., Rasmussen, J.M., Nardos, R., Entringer, S., Wadhwa, P.D., Buss, C. & Fair, D.A. (2018). Maternal IL-6 during pregnancy can be estimated from newborn brain connectivity and predicts future working memory in offspring. Nature Neuroscience, 21, 765-772.

Rasmussen, J.M., Graham, A.M., Entringer, S., Gilmore, J.H., Styner, M, Fair, D.A., Wadhwa, P.D, & Buss, C. (2018). Maternal Interleukin-6 concentration during pregnancy is associated with variation in frontolimbic white matter and cognitive development in early life. NeuroImage. S1053-8119(18)30316.

Graham, A.M., Rasmussen, J.M., Rudolph, M.D., Heim, C.M., Gilmore, J.H., Styner, M., Potkin, S.G., Entringer, S., Wadhwa, P.D., Fair, D.A., & Buss, C. (2018). Maternal systemic interleukin-6 during pregnancy is associated with newborn amygdala phenotypes and subsequent behavior at 2-years-of-age. Biological Psychiatry, 83(2), 109-119.

Graham, A.M., Pears, K.C.., Kim, H.K., Bruce, J., & Fisher, P.A. (2018).  Effects of a school readiness intervention on hypothalamic-pituitary-adrenal axis functioning and school adjustment for children in foster care. Development & Psychopathology, 2, 651-664.

Fair, D.A., Graham, A.M., & Mills, B. (2018). A role of early life stress on subsequent brain and behavioral development. Washington University Journal of Law & Policy, 57, 89-101.

Graham, A.M., Buss, C., Rasmussen, J.M., Rudolph, M.D., Demeter, D., Gilmore, J.H., Styner, M., Entringer, S., Wadhwa, P.D., & Fair, D.A. (2016). Implications of newborn amygdala connectivity for fear and cognitive development at 6-months-of-age. Developmental Cognitive Neuroscience, 18, 12-25.

Graham, A. M., Pfeifer, J.H., Fisher, P.A., Carpenter, W., & Fair, D.A. (2015). Early life stress is associated with default system integrity and emotionality during infancy. Journal of Child Psychology and Psychiatry, , 56(11), 1212-22.

Graham, A.M. & Fair, D.A. (2015). Commentary: Developmental connectomics to advance our understanding of typical and atypical brain development – a commentary on Vèrtes and Bullmore (2015). Journal of Child Psychology and Psychiatry, 56(3), 321-3.

Graham, A. M., Pfeifer, J.H., Fisher, P.A., Lin, W., Gao, W., & Fair, D.A. (2015). The potential of infant fMRI research and the study of early life stress as a promising exemplar. Developmental Cognitive Neuroscience, 12, 12-39.

Fisher, P.A., Mannering, A.M., van Scoyoc, A.E., Graham, A.M. (2013). Doing what we must: A translational neuroscience perspective on the importance of preventing placement instability among foster children. Child Welfare, 92(5), 9-36.

Bruce, J., Fisher, P.A., Graham, A.M., Moore, W.E., Peake, S. & Mannering, A.M. (2013). Patterns of brain activation in foster children and nonmaltreated children during an inhibitory control task. Development and Psychopathology, 25, 931–941.

Graham, A.M., Fisher, P.A., & Pfeifer, J.H. (2013). What sleeping babies hear: An fMRI study of interparental conflict and infants’ emotion processing. Psychological Science, 24(5), 782-789.

Berkman, E.T., Graham, A.M., & Fisher, P.A. (2012). Training self-control: A domain-general translational neuroscience approach. Child Development Perspectives, 6(4), 374-384.

Graham, A. M., Yockelson, M., Kim, H. K., Bruce, J.B., Pears, K.P., & Fisher, P.A (2012). Effects of maltreatment and early intervention on diurnal cortisol across the start of school: A pilot study. Child Abuse & Neglect, 36, 666-670.

Graham, A. M., Kim, H. K., & Fisher, P.A (2012). Partner aggression in high-risk families from birth to age 3: Associations with harsh parenting and child maladjustment. Journal of Family Psychology, 26(1), 105-114.