Publications | Infectious Diseases
Marissa Maier, MD - Professor of Medicine
Cara D Varley, Elliott Lowy, Emily J Cartwright, Timothy R Morgan, David B Ross, Karine Rozenberg-Ben-Dror, Lauren A Beste, Marissa M Maier, Success of the US Veterans Health Administration's Hepatitis C Virus Care Continuum in the Direct-acting Antiviral Era, Clinical Infectious Diseases, 2024;, ciae025, https://doi.org/10.1093/cid/ciae025
GARDELLA, Carolyn M. MD MPH1,2; BORGERDING, Joleen MS1; MAIER, Marissa M. MD3,4; BESTE, Lauren A. MD MSc1,5. Chlamydial and Gonococcal Infections and Adverse Reproductive Health Conditions among Patients Assigned Female at Birth in the Veterans Health Administration. Sexually Transmitted Diseases ():10.1097/OLQ.0000000000001932, January 26, 2024. | DOI: 10.1097/OLQ.0000000000001932
Cara Varley, MD, MPH - Assistant Professor of Medicine
Cara D Varley, Elliott Lowy, Emily J Cartwright, Timothy R Morgan, David B Ross, Karine Rozenberg-Ben-Dror, Lauren A Beste, Marissa M Maier, Success of the US Veterans Health Administration's Hepatitis C Virus Care Continuum in the Direct-acting Antiviral Era, Clinical Infectious Diseases, 2024;, ciae025, https://doi.org/10.1093/cid/ciae025
Kristina Bajema, M.D., M.Sc. - Assistant Professor of Medicine
George N. Ioannou, BMBCh, MS; Kristin Berry, PhD; Nallakkandi Rajeevan, PhD; Yuli Li, MS; Pradeep Mutalik, MD;Lei Yan, PhD; David Bui, PhD; Francesca Cunningham, PharmD; Denise M. Hynes, MPH, PhD, RN; Mazhgan Rowneki, MPH;Amy Bohnert, PhD, MHS; Edward J. Boyko, MD, MPH; Theodore J. Iwashyna, MD, PhD; Matthew L. Maciejewski, PhD;Thomas F. Osborne, MD; Elizabeth M. Viglianti, MD, MPH, MSc; Mihaela Aslan, PhD; Grant D. Huang, MPH, PhD; and Kristina L. Bajema, MD, MSc. Effectiveness of Nirmatrelvir–Ritonavir Against the Development of Post–COVID-19 Conditions Among U.S. Veterans: A Target Trial Emulation. Ann Intern Med. [Epub 31 October 2023]. doi:10.7326/M23-1394
Chris Evans, MD, MPH - Associate Professor of Medicine
Park, H., McCracken, C., Lininger, N., Varley, C., Sikka, M., Evans, C., . . . McGregor, J. (2023). Incidence and risk factors for clinically confirmed secondary bacterial infections in patients hospitalized for coronavirus disease 2019 (COVID-19). Infection Control & Hospital Epidemiology, 1-7. doi:10.1017/ice.2023.27
Marissa Maier, MD - Professor of Medicine
Villamagna, Angela Holly MD; Beste, Lauren A. MD, MSc; Borgerding, Joleen MS; Lowy, Elliott PhD; Hauser, Ronald G. MD; Ross, David MD, PhD; Maier, Marissa M. MD. Testing and Case Rates of Gonorrhea, Chlamydia, Syphilis, and HIV among People with Substance Use Disorders in the Veterans Health Administration. Journal of Addiction Medicine ():10.1097/ADM.0000000000001134, January 12, 2023. | DOI: 10.1097/ADM.0000000000001134
Bill Messer, MD, PhD - Associate Professor of Medicine
Diray-Arce J, Fourati S, Doni Jayavelu N, Patel R, Maguire C, Chang AC, Dandekar R, Qi J, Lee BH, van Zalm P, Schroeder A, Chen E, Konstorum A, Brito A, Gygi JP, Kho A, Chen J, Pawar S, Gonzalez-Reiche AS, Hoch A, Milliren CE, Overton JA, Westendorf K; IMPACC Network; Cairns CB, Rouphael N, Bosinger SE, Kim-Schulze S, Krammer F, Rosen L, Grubaugh ND, van Bakel H, Wilson M, Rajan J, Steen H, Eckalbar W, Cotsapas C, Langelier CR, Levy O, Altman MC, Maecker H, Montgomery RR, Haddad EK, Sekaly RP, Esserman D, Ozonoff A, Becker PM, Augustine AD, Guan L, Peters B, Kleinstein SH. Multi-omic longitudinal study reveals immune correlates of clinical course among hospitalized COVID-19 patients. Cell Rep Med. 2023 Jun 20;4(6):101079. doi: 10.1016/j.xcrm.2023.101079. Epub 2023 May 23. PMID: 37327781; PMCID: PMC10203880.
Powers JM, Lyski ZL, Weber WC, Denton M, Streblow MM, Mayo AT, Haese NN, Nix CD, Rodríguez-Santiago R, Alvarado LI, Rivera-Amill V, Messer WB, Streblow DN. Infection with chikungunya virus confers heterotypic cross-neutralizing antibodies and memory B-cells against other arthritogenic alphaviruses predominantly through the B domain of the E2 glycoprotein. PLoS Negl Trop Dis. 2023 Mar 13;17(3):e0011154. doi: 10.1371/journal.pntd.0011154. PMID: 36913428; PMCID: PMC10036167.
Bates TA, Leier HC, McBride SK, Schoen D, Lyski ZL, Lee DX, Messer WB, Curlin ME, Tafesse FG. An extended interval between vaccination and infection enhances hybrid immunity against SARS-CoV-2 variants. JCI Insight. 2023 Mar 8;8(5):e165265. doi: 10.1172/jci.insight.165265. PMID: 36701200; PMCID: PMC10077480.
Monica Sikka, MD - Associate Professor of Medicine
Solomon DA, Beieler AM, Levy S, Eaton EF, Sikka MK, Thornton A, Dhanireddy S. Perspectives on the Use of Outpatient Parenteral Antibiotic Therapy for People Who Inject Drugs: results from an online survey of infectious diseases clinicians. Open Forum Infect Dis. July 15, 20023. doi:10.1093/ofid/ofad372
Park HS, McCracken CM, Lininger N, Varley CD, Sikka MK, Evans C, Villamagna AH, Makadia JT, McGregor JC. Incidence and risk factors for clinically confirmed secondary bacterial infections in patients hospitalized for coronavirus disease 2019 (COVID-19). Infect Control Hosp Epidemiol. 2023 May 15:1-7. doi: 10.1017/ice.2023.27.
Lynne Strasfeld, MD - Associate Professor of Medicine
Fontana L, Strasfeld L, Hakki M. Pseudomonas aeruginosa ExoU-associated virulence in hematopoietic cell transplant and hematologic malignancy patients. Blood Adv. 2023 May 22:bloodadvances.2023009806. doi: 10.1182/bloodadvances.2023009806. Epub ahead of print. PMID: 37216281.
Zou J, Rivera Sarti JE, Strasfeld L. Daptomycin-associated pulmonary toxicity sans eosinophilia in a hematopoietic cell transplant recipient with profound leukopenia. Transpl Infect Dis. 2023 Jun;25(3):e14029. doi: 10.1111/tid.14029. Epub 2023 Feb 14. PMID: 36787236.
Cara Varley, MD, MPH - Assistant Professor of Medicine
Park, H., McCracken, C., Lininger, N., Varley, C., Sikka, M., Evans, C., . . . McGregor, J. (2023). Incidence and risk factors for clinically confirmed secondary bacterial infections in patients hospitalized for coronavirus disease 2019 (COVID-19). Infection Control & Hospital Epidemiology, 1-7. doi:10.1017/ice.2023.27
Ku JH, Bruxvoort KJ, Salas SB, Varley CD, Casey JA, Raphael E, et al. Multi-drug resistance of Escherichia coli from outpatient uncomplicated urinary tract infections in a large U.S. integrated health care organization. Open Forum Infectious Diseases. 2023:ofad287.
Mingora, CM, Bullington, W, Faasuamalie, PE, Levin, A, Porter, G, Stadnick, R, Varley CD, Addrizzo-Harris D, Daley CL, Olivier KN, Winthrop KL, Dorman SE, Flume, PA (2023). Long Term Safety and Tolerability of Omadacycline for the Treatment of Mycobacterium Abscessus Infections. Open Forum Infectious Diseases, ofad335. doi:10.1093/ofid/ofad335. https://academic.oup.com/ofid/advance-article/doi/10.1093/ofid/ofad335/7218331
Ku, J., Varley, C., Epson, E., Deodhar, A., & Winthrop, K. (2023). Tuberculosis of prosthetic knee with simultaneous pulmonary infection with nontuberculous mycobacteria. Radiology of Infectious Diseases, 10(1), 30-32. doi:10.4103/rid.Rid_42_22. https://www.ridiseases.org/article.asp?issn=2352-6211;year=2023;volume=10;issue=1;spage=30;epage=32;aulast=Ku
Varley CD, Streifel AC, Bair AM, et al. Nontuberculous Mycobacterial Pulmonary Disease in the Immunocompromised Host. Clinics in Chest Medicine 2023. DOI: https://doi.org/10.1016/j.ccm.2023.06.007.
Cristancho-Rojas C, Varley CD, Lara SC, Kherabi Y, Henkle E, Winthrop KL. Epidemiology of Mycobacterium abscessus. Clin Microbiol Infect. 2023 Sep 29:S1198-743X(23)00480-9. doi: 10.1016/j.cmi.2023.08.035. Epub ahead of print. PMID: 37778416
Holly Villamagna, MD - Assistant Professor of Medicine
Villamagna, Angela Holly MD; Beste, Lauren A. MD, MSc; Borgerding, Joleen MS; Lowy, Elliott PhD; Hauser, Ronald G. MD; Ross, David MD, PhD; Maier, Marissa M. MD. Testing and Case Rates of Gonorrhea, Chlamydia, Syphilis, and HIV among People with Substance Use Disorders in the Veterans Health Administration. Journal of Addiction Medicine ():10.1097/ADM.0000000000001134, January 12, 2023. | DOI: 10.1097/ADM.0000000000001134
Marissa Maier, MD - Professor of Medicine
Lee TH, Hunt CM, Maier MM, Lowy E, Beste LA. Hepatitis B Virus-Related Care Quality In Patients With Hepatitis B/Hiv Coinfection Versus Hepatitis B Monoinfection: A National Cohort Study. Clin Infect Dis. 2022 Mar 29:ciac227. doi: 10.1093/cid/ciac227. Epub ahead of print. PMID: 35349635.
Rozenberg-Ben-Dror, K, Maier, MM, Beste, L, Lowy, E, Chartier, M, Ross, D, et al. Improving quality of hepatitis B care in the Veteran's Health Administration. Clinical Liver Disease. 2022; 19: 213– 218. https://doi.org/10.1002/cld.1237
Hauser RG, Bhargava A, Brandt CA, Chartier M, Maier MM (2022) Graphical analysis of guideline adherence to detect systemwide anomalies in HIV diagnostic testing. PLOS ONE 17(7): e0270394. https://doi.org/10.1371/journal.pone.0270394
Lauren A Beste, Shimrit Keddem, Joleen Borgerding, Elliott Lowy, Carolyn Gardella, Lorenzo McFarland, Emily Comstock, Giuseppe Allan Fonseca, Puja Van Epps, Michael Ohl, Ronald G Hauser, David Ross, Marissa M Maier, Sexually transmitted infection testing in the national Veterans Health Administration patient cohort during the COVID-19 pandemic, Open Forum Infectious Diseases, 2022;, ofac433, https://doi.org/10.1093/ofid/ofac433
Keddem, S., Maier, M., Gardella, C. et al. Gonorrhea and Chlamydia Testing and Case Rates Among Women Veterans in the Veterans Health Administration. J GEN INTERN MED (2022). https://doi.org/10.1007/s11606-022-07578-2
Tim Menza, MD, PhD - Assistant Professor of Medicine
Menza TW, Berry SA, Dombrowski J, Cachay E, Dionne-Odom J, Christopoulos K, Crane HM, Kitahata MM, Mayer KH. Syphilis Testing and Diagnosis Among People With Human Immunodeficiency Virus (HIV) Engaged in Care at 4 US Clinical Sites, 2014-2018. Clin Infect Dis. 2022 Aug 31;75(3):483-492. doi: 10.1093/cid/ciab944. PMID: 34788808; PMCID: PMC9427144.
Monica Sikka, MD - Associate Professor of Medicine
Varley CD, Conte M, Streifel AC, Winders B, Sikka MK. Screening for co-infections in patients with substance use disorders and severe bacterial infections. Ther Adv Infect Dis. 2022 Oct 17;9:20499361221132132. doi: 10.1177/20499361221132132. PMID: 36277297; PMCID: PMC9580098.
Lynne Strasfeld, MD - Associate Professor of Medicine
Strasfeld L. COVID-19 and HSCT (Hematopoietic stem cell transplant). Best Pract Res Clin Haematol. 2022 Sep;35(3):101399. doi: 10.1016/j.beha.2022.101399. Epub 2022 Oct 8. PMID: 36494150; PMCID: PMC9547387.
Zimmer AJ, Stohs E, Meza J, Arnold C, Baddley JW, Chandrasekar P, El Boghdadly Z, Gomez CA, Maziarz EK, Montoya JG, Pergam S, Rolston KV, Satlin MJ, Satyanarayana G, Shoham S, Strasfeld L, Taplitz R, Walsh TJ, Young JH, Zhang Y, Freifeld AG. Bloodstream Infections in Hematologic Malignancy Patients With Fever and Neutropenia: Are Empirical Antibiotic Therapies in the United States Still Effective? Open Forum Infect Dis. 2022 May 18;9(7):ofac240. doi: 10.1093/ofid/ofac240. PMID: 35854988; PMCID: PMC9277632.
Zhang L, Tan FC, Strasfeld L, Hakki M, Kirienko NV. Long-Term Dominance of Carbapenem-Non-Susceptible Pseudomonas aeruginosa ST111 in Hematologic Malignancy Patients and Hematopoietic Cell Transplant Recipients. Front Cell Infect Microbiol. 2022 Jun 16;12:904602. doi: 10.3389/fcimb.2022.904602. PMID: 35782141; PMCID: PMC9244782.
Cara Varley, MD, MPH - Assistant Professor of Medicine
Varley CD, Winthrop KL. Nontuberculous Mycobacteria: Diagnosis and Therapy. Clinics in Chest Medicine. 2022 March; 43(1):89-98. https://authors.elsevier.com/a/1efRPzzkxqYxc
Varley CD, Rogers LM, Dixon BR, Bernard SC, Lacy DB, Sulpizio E, Aronoff DM, Townes JM. Anaerobe. 2022 Jan 24; 102520. doi: 10.1016/j.anaerobe.2022.102520. PubMed PMID: 35085782. https://authors.elsevier.com/a/1eV%7EU3qfpmWqtN
Streifel A, Varley C, Ham Y, Sikka M, Lewis J. The challenge of antibiotic selection in prosthetic joint infections due to Corynebacterium striatum: a case report. BMC Infectious Diseases. 2022/03; 22(1):290. doi: 10.1186/s12879-022-07270-0. https://rdcu.be/cJ20j
Conte M, Schneider B, Varley CD, Streifel AC, Sikka MK. Description and outcomes of patients with substance use disorder with serious bacterial infections who had a multidisciplinary care conference. Therapeutic Advances in Infectious Disease. January 2022. doi:10.1177/20499361221117974
Varley CD, Conte M, Streifel AC, Winders B, Sikka MK. Screening for co-infections in patients with substance use disorders and severe bacterial infections. Ther Adv Infect Dis. 2022 Oct 17;9:20499361221132132. doi: 10.1177/20499361221132132. PMID: 36277297; PMCID: PMC9580098.
Quittner, AL, Varley, CD, Henkle, E. (2022). Non-CF Bronchiectasis and Nontuberculous Mycobacteria: Integration of Mental Health and Quality of Life into Patient Care. In: Teneback, C.C., Garcia, B. (eds) Bronchiectasis. Respiratory Medicine. Humana, Cham. https://doi.org/10.1007/978-3-031-12926-1_10
Stone Doggett, MD - Associate Professor of Medicine
New Scalable Synthetic Routes to ELQ-300, ELQ-316, and Other Antiparasitic Quinolones. Sovitj Pou, Rozalia A. Dodean, Lisa Frueh, Katherine M. Liebman, Rory T. Gallagher, Haihong Jin, Robert T. Jacobs, Aaron Nilsen, David R. Stuart, J. Stone Doggett, Michael K. Riscoe, and Rolf W. Winter Organic Process Research & Development 2021 25 (8), 1841-1852. DOI: 10.1021/acs.oprd.1c00099
Endochin-like quinolones (ELQs) and bumped kinase inhibitors (BKIs): Synergistic and additive effects of combined treatments against Neospora caninum infection in vitro and in vivo. Anghel N, Imhof D, Winzer P, Balmer V, Ramseier J, Haenggeli K, Choi R, Hulverson MA, Whitman GR, Arnold SLM, Ojo KK, Van Voorhis WC, Doggett JS, Ortega-Mora LM, Hemphill A. Int J Parasitol Drugs Drug Resist. 2021 Aug 28;17:92-106. doi: 10.1016/j.ijpddr.2021.08.007. Online ahead of print. PMID: 34482255
Effective Therapy Targeting Cytochrome bc1 Prevents Babesia Erythrocytic Development and Protects from Lethal Infection. Chiu JE, Renard I, Pal AC, Singh P, Vydyam P, Thekkiniath J, Kumar M, Gihaz S, Pou S, Winter RW, Dodean R, Frueh L, Nilsen AC, Riscoe MK, Doggett JS, Mamoun CB. Antimicrob Agents Chemother. 2021 Aug 17;65(9):e0066221. doi: 10.1128/AAC.00662-21. Epub 2021 Aug 17. PMID: 34152821
Cytochrome b Drug Resistance Mutation Decreases Babesia Fitness in the Tick Stages but not the Mammalian Erythrocytic Cycle. Chiu JE, Renard I, George S, Pal A, Alday H, Narasimhan S, Riscoe MK, Doggett JS, Ben Mamoun C. J Infect Dis. 2021 Jun 17:jiab321. doi: 10.1093/infdis/jiab321. Online ahead of print. PMID: 34139755
In vitro activity, safety and in vivo efficacy of the novel bumped kinase inhibitor BKI-1748 in non-pregnant and pregnant mice experimentally infected with Neospora caninum tachyzoites and Toxoplasma gondii oocysts. Imhof D, Anghel N, Winzer P, Balmer V, Ramseier J, Hänggeli K, Choi R, Hulverson MA, Whitman GR, Arnold SLM, Ojo KK, Van Voorhis WC, Doggett JS, Ortega-Mora LM, Hemphill A. Int J Parasitol Drugs Drug Resist. 2021 Aug;16:90-101. doi: 10.1016/j.ijpddr.2021.05.001. Epub 2021 May 18. PMID: 34030110 Free PMC article.
A novel fragmented mitochondrial genome in the protist pathogen Toxoplasma gondii and related tissue coccidia. Namasivayam S, Baptista RP, Xiao W, Hall EM, Doggett JS, Troell K, Kissinger JC. Genome Res. 2021 May;31(5):852-865. doi: 10.1101/gr.266403.120. Epub 2021 Apr 27. PMID: 33906963 Free PMC article.
Acridones Are Highly Potent Inhibitors of Toxoplasma gondii Tachyzoites. Alday PH, McConnell EV, Boitz Zarella JM, Dodean RA, Kancharla P, Kelly JX, Doggett JS. ACS Infect Dis. 2021 Jul 9;7(7):1877-1884. doi: 10.1021/acsinfecdis.1c00016. Epub 2021 Mar 16. PMID: 33723998 Free PMC article.
One health therapeutics: Target-Based drug development for cryptosporidiosis and other apicomplexa diseases. Van Voorhis WC, Hulverson MA, Choi R, Huang W, Arnold SLM, Schaefer DA, Betzer DP, Vidadala RSR, Lee S, Whitman GR, Barrett LK, Maly DJ, Riggs MW, Fan E, Kennedy TJ, Tzipori S, Doggett JS, Winzer P, Anghel N, Imhof D, Müller J, Hemphill A, Ferre I, Sanchez-Sanchez R, Ortega-Mora LM, Ojo KK. Vet Parasitol. 2021 Jan;289:109336. doi: 10.1016/j.vetpar.2020.109336. Epub 2020 Dec 15. PMID: 33418437 Review.
Morgan Hakki, MD - Associate Professor of Medicine
"American Society for Transplantation and Cellular Therapy Series: #3-Prevention of Cytomegalovirus Infection and Disease After Hematopoietic Cell Transplantation " https://doi.org/10.1016/j.jtct.2021.05.001
"Emergence of non-susceptibility during persistent Pseudomonas aeruginosa bacteraemia in haematopoietic cell transplant recipients and haematological malignancy patients" https://doi.org/10.1093/jacamr/dlab125
Marissa Maier, MD - Professor of Medicine
Ina Gylys-Colwell, MS, Elliott Lowy, PhD, Joleen Borgerding, MS, Puja Van Epps, MD, Michael Ohl, MD MSPH, Ronald G Hauser, MD, Maggie Chartier, PsyD, MPH, Marissa M Maier, MD, Lauren Beste, MD MSc, Differences in syphilis incidence using a laboratory algorithm in people with and without HIV in an eleven-year nationwide cohort study, Open Forum Infectious Diseases, 2021;, ofab030, https://doi.org/10.1093/ofid/ofab030
Kobayashi K, Van Epps P, Maier M, Beste L, Beck B, Alexander B, Ohl M. Discussion and Initiation of HIV pre-exposure prophylaxis were rare following diagnoses of sexually transmitted infections among Veterans. Journal of General Internal Medicine. In press
Timothy Menza, MD, PhD - Assistant Professor of Medicine
Menza, T.W., L Hixson, L Lipira, L Drach, Social determinants of health and care outcomes among people with HIV in the United States. OFID, 2021.
Lipira, L., G. Leichtling, R.R Cook, J.M. Leahy, E.R. Orellana, P.T. Korthuis, T.W. Menza, Predictors of having naloxone in urban and rural Oregon: findings from NHBS and the OR-HOPE study. Drug and Alcohol Dependence, 2021.
Todd, J.V., Collins, N.V., Oakley, J., Menza, T.W., Barber, M., Kasarskis, I., Weresch, A., Morgan, S., Jellison, J., Mishra, N., Pérez, A., Karki, S, Automating Case Reporting of Chlamydia and Gonorrhea to Public Health Authorities in Oregon Clinics. Sex Transm Dis, 2021.
Allan-Blitz, L.T., T.W. Menza*, V. Cummings, C.A. Gaydos, L. Wilton, and K.H. Mayer, Multifactorial Correlates of Incident Bacterial Sexually Transmitted Infections Among Black Men Who have Sex with Men Recruited in 6 US Cities (HPTN 061). Sex Transm Dis, 2021.
Menza, T.W., A.I. Zlot, J. Garai, S. Humphrey, and J. Ferrer, The impact of the SARS-CoV-2 pandemic on HIV and bacterial sexually transmitted infection testing and diagnosis in Oregon. Sex Transm Dis, 2021.
Menza, T.W., J. Garai, J. Ferrer, and J. Hecht, Rapid Uptake of Home-Based HIV Self-testing During Social Distancing for SARS-CoV2 Infection in Oregon. AIDS Behav, 2021. 25(1): p. 167-170.
John Townes, MD - Professor of Medicine
Horve PF, Dietz LG, Fretz M, Constant DA, Wilkes A, Townes JM, Martindale RG, Messer WB, Van Den Wymelenberg KG. Identification of SARS-CoV-2 RNA in healthcare heating, ventilation, and air conditioning units. Indoor Air. 2021 Jun 29. doi: 10.1111/ina.12898. Epub ahead of print. PMID: 34189769.
Cara Varley, MD, MPH - Assistant Professor of Medicine
Varley CD, Winthrop KL. Long-Term Safety of Rituximab (Risks of Viral and Opportunistic Infections). Curr Rheumatol Rep. 2021 Jul 16;23(9):74. doi: 10.1007/s11926-021-01037-3. Review. PMID: 34269903.
Varley CD, Winthrop KL. Chapter 8: Vaccination before or during pregnancy. In: Karen S, Eliza C, Monika Ø, editors. Practical Management of the Pregnant Patient with Rheumatic Disease. New York, NY: Oxford University Press; March 28, 2021.
Varley CD, Ku JH, Winthrop KL. COVID-19 pandemic management and the rheumatology patient. Best Pract Res Clin Rheumatol. 2021 Mar;35(1):101663. doi: 10.1016/j.berh.2021.101663. Epub 2021 Jan 13. Review. PubMed PMID: 33536145;
Erin Bonura, MD, MCR - Associate Professor of Medicine
Villamagna AH, Bonura EM. Infectious diseases simulation for medical students: experiential instruction on personal protective equipment. MedEdPORTAL. 2020;16:11031. https://doi.org/10.15766/mep_2374-8265.11031
Sunwen Chou, MD - Professor of Medicine
Douglas CM, Barnard R, Holder D, Leavitt R, Levitan D, Maguire M, Nickle D, Teal V, Wan H, van Alewijk D, van Doorn L, Chou S, Strizki J. Letermovir resistance analysis in a clinical trial of cytomegalovirus prophylaxis for hematopoietic stem cell transplant recipients. Journal of Infectious Diseases. DOI: 10.1093/infdis/jiz577
Chou S. Advances in the genotypic diagnosis of cytomegalovirus antiviral drug resistance. Antiviral Research. DOI: 10.1016/j.antiviral.2020.104711
Chou S, Song K, Wu J, Bo T, Crumpacker C. Drug resistance mutations and associated phenotypes detected in clinical trials of maribavir for treatment of cytomegalovirus infection. Journal of Infectious Diseases. DOI: 10.1093/infdis/jiaa462
J. Stone Doggett, MD - Associate Professor of Medicine
Doggett JS, Schultz T, Miller AJ, Bruzual I, Pou S, Winter R, Dodean R, Zakharov LN, Nilsen A, Riscoe MK, Carruthers VB. Orally Bioavailable Endochin-like Quinolone Carbonate Ester Prodrug Reduces Toxoplasma gondii Brain Cysts. Antimicrob Agents Chemother. 2020 Jun 15:AAC.00535-20. doi:10.1128/AAC.00535-20. Epub ahead of print. PMID: 32540978.
https://pubmed.ncbi.nlm.nih.gov/32540978/
Morgan Hakki, MD - Associate Professor of Medicine
Hakki M. Moving past ganciclovir and foscarnet: advances in CMV therapy. Current Hematol Malig Rep. https://pubmed.ncbi.nlm.nih.gov/31981100/
Fontana L, Perlin DS, Zhao Y, Noble BN, Lewis JS II, Strasfeld L, Hakki M. Isavuconazole prophylaxis in patients with hematologic malignancies and hematopoietic-cell transplant recipients. Clin Infect Dis. Selected as one of “Top 10 papers in medical mycology – 2019” by the Mycoses Study Group Education and Research Consortium. https://pubmed.ncbi.nlm.nih.gov/30958538/
Timothy Menza, MD, PhD - Assistant Professor of Medicine
Philbin, M.M., T.W. Menza, S. LeGrand, K.E. Muessig, and L.B. Hightow-Weidman. Structural-level racial-, sexuality-, and HIV-related discrimination and subsequent criminal justice involvement among young, Black men who have sex with men in North Carolina. Stigma and Health, 2020.
Menza, T.W., L. Lipira, A. Bhattarai, V.C. Leon, and E.R. Orellana, Prevalence and correlates of transactional sex among women of low socioeconomic status in Portland, OR. BMC Women's Health, 2020. 20(1): p. 219.
McMahan, V.M., C. Moreno, A. Al-Tayyib, T.W. Menza, E.R. Orellana, A. Bhattarai, J.D. Stekler, and S.N. Glick, Pre-exposure Prophylaxis Awareness and Use Among Cisgender Men Who Have Sex With Men and Use Methamphetamine in 3 Western US Cities. Sex Transm Dis, 2020. 47(4): p. 217-223.
Capizzi, J., J. Leahy, H. Wheelock, J. Garcia, L. Strnad, M. Sikka, H. Englander, A. Thomas, P.T. Korthuis, and T.W. Menza, Population-based trends in hospitalizations due to injection drug use-related serious bacterial infections, Oregon, 2008 to 2018. PLoS One, 2020. 15(11): p. e0242165.
Bill Messer, MD, PhD - Associate Professor of Medicine
Nix CD, Salberg J, Coulter FJ, Kareko BW, Lyski ZL, Booty BL, Messer WB. Potency and breadth of human primary ZIKV immune sera shows that Zika viruses cluster antigenically as a single serotype. PLoS Negl Trop Dis. 2020 Apr;14(4):e0008006. doi: 10.1371/journal.pntd.0008006. eCollection 2020 Apr. PubMed PMID: 32282800.
Monica Sikka, MD - Associate Professor of Medicine
Streifel, AC, Sikka MK. The Urgent Need for Medicare Reimbursement for Home Infusion Antibiotics amidst a Pandemic. Clin Infect Dis. https://doi.org/10.1093/cid/ciaa658
Capizzi J, Leahy J, Wheelock H, Garcia J, Strnad L, Sikka M, Englander H, Thomas A, Korthuis PT, Menza TW. Population-based trends in hospitalizations due to injection drug use-related serious bacterial infections, Oregon, 2008 to 2018. PLoS One. 2020 Nov 9;15(11):e0242165. doi: 10.1371/journal.pone.0242165. PMID: 33166363.
Luke Strnad, MD - Associate Professor of Medicine
Capizzi J, Leahy J, Wheelock H, Garcia J, Strnad L, Sikka M, Englander H, Thomas A, Korthuis PT, Menza TW. Population-based trends in hospitalizations due to injection drug use-related serious bacterial infections, Oregon, 2008 to 2018. PLoS One. 2020 Nov 9;15(11):e0242165. doi: 10.1371/journal.pone.0242165. PMID: 33166363.
Holly Villamagna, MD - Assistant Professor of Medicine
Villamagna AH, Bonura EM. Infectious diseases simulation for medical students: experiential instruction on personal protective equipment. MedEdPORTAL. 2020;16:11031. https://doi.org/10.15766/mep_2374-8265.11031
Sunwen Chou, MD - Professor of Medicine
Chemaly RF, Chou S, Einsele H, Griffiths P, Avery R, Razonable RR, Mullane KM, Kotton C, Lundgren J, Komatsu TE, Lischka P, Josephson F, Douglas CM, Umeh O, Miller V, Ljungman P. Definitions of resistant and refractory cytomegalovirus infection and disease in transplant recipients for use in clinical trials. Clinical Infectious Diseases. DOI: 10.1093/cid/ciy696
Chou S, Wu J, Song K, Bo T. Novel UL97 drug resistance mutations identified at baseline in a clinical trial of maribavir for resistant or refractory cytomegalovirus infection. Antiviral Research. DOI: 10.1016/j.antiviral.2019.104616
J. Stone Doggett, MD - Associate Professor of Medicine
Hulverson MA, Bruzual I, McConnell EV, Huang W, Vidadala RSR, Choi R, Arnold SLM, Whitman GR, McCloskey MC, Barrett LK, Rivas KL, Scheele S, DeRocher AE, Parsons M, Ojo KK, Maly DJ, Fan E, Van Voorhis WC, Doggett JS. Pharmacokinetics and In Vivo Efficacy of Pyrazolopyrimidine, Pyrrolopyrimidine, and 5-Aminopyrazole-4-Carboxamide Bumped Kinase Inhibitors against Toxoplasmosis. J Infect Dis. 2019 Apr 16;219(9):1464-1473. doi: 10.1093/infdis/jiy664. PMID: 30423128; PMCID: PMC6467197.
https://pubmed.ncbi.nlm.nih.gov/30423128/
Morgan Hakki, MD - Associate Professor of Medicine
Petersen J, Lindner C, Hakki M. Incidence and outcomes of bacterial bloodstream infections during acute graft versus host disease involving the gastrointestinal tract following hematopoietic-cell transplant. Biol Blood Marrow Transplant. Selected for editorial commentary: “Intestinal Acute Graft-versus-Host Disease: A Bug Highway to the Bloodstream”. Horwitz M.E. Biol Blood Marrow Transplant. https://pubmed.ncbi.nlm.nih.gov/31002988/
Hakki M, Humphries RM, Hamarajata P, Tallman GB, Shields RK, Mettus RT, Doi Y, Lewis JS II. Fluoroquinolone prophylaxis selects for meropenem non-susceptible Pseudomonas aeruginosa in patients with hematologic malignancies and hematopoietic-cell transplant recipients. Clinical Infectious Diseases. https://pubmed.ncbi.nlm.nih.gov/30256922/
Bill Messer, MD, PhD - Associate Professor of Medicine
Kareko BW, Booty BL, Nix CD, Lyski ZL, Slifka MK, Amanna IJ, Messer WB. Persistence of Neutralizing Antibody Responses Among Yellow Fever Virus 17D Vaccinees Living in a Nonendemic Setting. J Infect Dis. 2019. Epub 2019/09/24. doi: 10.1093/infdis/jiz374. PubMed PMID: 31545367
Lyski ZL, Messer WB. Approaches to Interrogating the Human Memory B-Cell and Memory-Derived Antibody Repertoire Following Dengue Virus Infection. Front Immunol. 2019;10:1276. Epub 2019/06/28. doi: 10.3389/fimmu.2019.01276. PubMed PMID: 31244836; PMCID: PMC6562360.
Fontana L, Bonura E, Lyski Z, Messer W. The Brief Case: Klebsiella variicola-Identifying the Misidentified. J Clin Microbiol. 2019;57(1). Epub 2019/01/04. doi: 10.1128/JCM.00826-18. PubMed PMID: 30602547; PMCID: PMC6322460.
Fontana L, Bonura E, Lyski Z, Messer W. Closing the Brief Case: Klebsiella variicola-Identifying the Misidentified. J Clin Microbiol. 2019;57(1). Epub 2019/01/04. doi: 10.1128/JCM.00825-18. PubMed PMID: 30602546; PMCID: PMC6322464.
Monica Sikka, MD - Associate Professor of Medicine
Oda G, Winters MA, Pacheco SM, Sikka MK, Bleasdale SC, Dunn B, Boswell E, Winters B, Bumsted A, Frisch J, Holodniy M. Clusters of nontuberculous mycobacteria linked to water sources at three Veterans Affairs medical centers. Infection Control & Hospital Epi. https://doi.org/10.1017/ice.2019.342
Streifel AC, Sikka MK, Bowen CD, Lewis JS 2nd; Dalbavancin use in an academic medical center and associated cost-savings. Int J Antimicrob Agents. https://doi.org/10.1016/j.ijantimicag.2019.08.007
Bleasdale SC, Sikka MK, Moritz DC, Fritzen-Pedicini C, Stiehl E, Brosseau LM, Jones RM. Experience of Chicagoland acute care hospitals in preparing for Ebola virus disease, 2014-2015. J Occup Environ Hyg. https://doi.org/10.1080/15459624.2019.1628966
Luke Strnad, MD - Associate Professor of Medicine
Liu C, Strnad L, Beekmann SE, Polgreen PM, Chambers HF. Clinical Practice Variation Among Adult Infectious Disease Physicians in the Management of Staphylococcus aureus Bacteremia. Clin Infect Dis. https://pubmed.ncbi.nlm.nih.gov/30601989/
Tapper EB, Strnad L, Shmerling R. Reducing the Burden of False-Positive Tests: It Is Time to Optimize Diagnostic Testing for Undifferentiated Conditions. Mayo Clin Proc. https://pubmed.ncbi.nlm.nih.gov/31272564/
Nathavitharana RR, Strnad L, Lederer PA, Shah M, Hurtado RM. Top Questions in the Diagnosis and Treatment of Pulmonary M. abscessus Disease. Open Forum Infect Dis. https://pubmed.ncbi.nlm.nih.gov/31289727/
Shete PB, Farr K, Strnad L, Gray CM, Cattamanchi A. Diagnostic accuracy of TB-LAMP for pulmonary tuberculosis: a systematic review and meta-analysis. BMC Infect Dis. https://pubmed.ncbi.nlm.nih.gov/30890135/
Book Chapter: Luke Strnad and Kevin Winthrop. Mycobacterium avium Complex. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, 9th Edition, ed by Bennett et al.
Erin Bonura, MD, MCR - Associate Professor of Medicine
Factors Influencing Selection of Infectious Diseases Training for Military Internal Medicine Residents.
Barsoumian AE, Hartzell JD, Bonura EM, Ressner RA, Whitman TJ, Yun HC.
Clin Infect Dis. 2018 Oct 30;67(10):1582-1587. doi: 10.1093/cid/ciy322.
PMID: 29912315
Case Report: Conjunctival Infestation with Thelazia gulosa: A Novel Agent of Human Thelaziasis in the United States.
Bradbury RS, Breen KV, Bonura EM, Hoyt JW, Bishop HS.
Am J Trop Med Hyg. 2018 Apr;98(4):1171-1174. doi: 10.4269/ajtmh.17-0870. Epub 2018 Feb 8.
PMID: 29436343 F
Sunwen Chou, MD - Professor of Medicine
Kotton CN, Kumar D, Caliendo AM, Huprikar S, Chou S, Danziger-Isakov L, Humar A. The third international consensus guidelines on the management of cytomegalovirus in solid organ transplantation. Transplantation. DOI: 10.1097/TP.0000000000002191
Chou S, Satterwhite LE, Ercolani RJ. New locus of drug resistance in the human cytomegalovirus UL56 gene revealed by in vitro exposure to letermovir and ganciclovir. Antimicrobial Agents and Chemotherapy. DOI: 10.1128/AAC.00922-18
Chou S, Ercolani RJ, Derakhchan K. Antiviral activity of maribavir in combination with other drugs active against human cytomegalovirus. Antiviral Research. DOI: 10.1016/j.antiviral.2018.07.013
Cherrier L, Nasar A Goodlet KJ, Nailor MD, Tokman S, Chou S. Emergence of letermovir resistance in a lung transplant recipient with ganciclovir-resistant cytomegalovirus infection. American Journal of Transplantation. DOI: 10.1111/ajt.15135
J. Stone Doggett, MD - Associate Professor of Medicine
McConnell EV, Bruzual I, Pou S, Winter R, Dodean RA, Smilkstein MJ, Krollenbrock A, Nilsen A, Zakharov LN, Riscoe MK, Doggett JS. Targeted Structure-Activity Analysis of Endochin-like Quinolones Reveals Potent Qi and Qo Site Inhibitors of Toxoplasma gondii and Plasmodium falciparum Cytochrome bc1 and Identifies ELQ-400 as a Remarkably Effective Compound against Acute Experimental Toxoplasmosis. ACS Infect Dis. 2018 Nov 9;4(11):1574-1584. doi: 10.1021/acsinfecdis.8b00133. Epub 2018 Aug 30. PMID: 30117728; PMCID: PMC6884402.
https://pubmed.ncbi.nlm.nih.gov/30117728/
Kirkman LA, Zhan W, Visone J, Dziedziech A, Singh PK, Fan H, Tong X, Bruzual I, Hara R, Kawasaki M, Imaeda T, Okamoto R, Sato K, Michino M, Alvaro EF, Guiang LF, Sanz L, Mota DJ, Govindasamy K, Wang R, Ling Y, Tumwebaze PK, Sukenick G, Shi L, Vendome J, Bhanot P, Rosenthal PJ, Aso K, Foley MA, Cooper RA, Kafsack B, Doggett JS, Nathan CF, Lin G. Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance. Proc Natl Acad Sci U S A. 2018 Jul 17;115(29):E6863-E6870. doi: 10.1073/pnas.1806109115. Epub 2018 Jul 2. PMID: 29967165; PMCID: PMC6055138.
https://pubmed.ncbi.nlm.nih.gov/29967165/
Morgan Hakki, MD - Associate Professor of Medicine
Hakki M, Lewis JS II. Ceftolozane-tazobactam therapy for multidrug-resistant Pseudomonas aeruginosa infections in patients with hematologic malignancies and hematpoeitic-cell transplant recipients. Infection. https://pubmed.ncbi.nlm.nih.gov/29460229/
Bill Messer, MD, PhD - Associate Professor of Medicine
Li SK, Messer WB. Burkholderia cepacia complex Cervical Osteomyelitis in an Intravenous Drug User. Case Rep Infect Dis. 2018;2018:7638639. Epub 2018/10/03. doi: 10.1155/2018/7638639. PubMed PMID: 30271645; PMCID: PMC6151243.
Leier HC, Messer WB, Tafesse FG. Lipids and pathogenic flaviviruses: An intimate union. PLoS Pathog. 2018;14(5):e1006952. Epub 2018/05/11. doi: 10.1371/journal.ppat.1006952. PubMed PMID: 29746606; PMCID: PMC5944919.
Monica Sikka, MD - Associate Professor of Medicine
Wenzler E, Bleasdale SC, Sikka M, Bunnell KL, Finnemeyer M, Rosenkranz SL, Danziger LH, Rodvold KA; Antibacterial Resistance Leadership Group. Phase I Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Two Dosing Regimens of Oral Fosfomycin Tromethamine in Healthy Adult Participants. Antimicrobial Agents and Chemotherapy. https://doi.org/10.1128/AAC.00464-18
Bunnell KL, Pai, MP, Sikka M, Bleasdale, S, Wenzler E, Danziger LH, Rodvold KA. Pharmacokinectics of Telavancin at Fixed Doses in Normal-Body-Weight and Obese (Classes I,II, and III, Adult Subjects. Antimicrobial Agents and Chemotherapy. https://doi.org/10.1128/AAC.02475-17
Luke Strnad, MD - Associate Professor of Medicine
Strnad L, Winthrop KL. Treatment of Mycobacterium abscessus Complex. Semin Respir Crit Care Med. https://pubmed.ncbi.nlm.nih.gov/30071551/
Farr K, Ravindran R, Strnad L, Chang E, Chaisson LH, Yoon C, Worodria W, Andama A, Ayakaka I, Bbosa Nalwanga P, Byanyima P, Kalema N, Kaswabuli S, Katagira W, Aman KD, Musisi E, Tumwine NW, Sanyu I, Ssebunya R, Davis JL, Huang L, Khan IH, Cattamanchi A. Diagnostic performance of blood inflammatory markers for tuberculosis screening in people living with HIV. PLoS One. https://pubmed.ncbi.nlm.nih.gov/30352099/
Book Chapter: Katie Raffel and Luke Strnad. Infectious Diseases. First Aid for the Internal Medicine Boards, 4th Edition, ed by Le et al.