Publications | Infectious Diseases

Erin Bonura, MD, MCR - Associate Professor of Medicine

Factors Influencing Selection of Infectious Diseases Training for Military Internal Medicine Residents.
Barsoumian AE, Hartzell JD, Bonura EM, Ressner RA, Whitman TJ, Yun HC.
Clin Infect Dis. 2018 Oct 30;67(10):1582-1587. doi: 10.1093/cid/ciy322.
PMID: 29912315

Case Report: Conjunctival Infestation with Thelazia gulosa: A Novel Agent of Human Thelaziasis in the United States.
Bradbury RS, Breen KV, Bonura EM, Hoyt JW, Bishop HS.
Am J Trop Med Hyg. 2018 Apr;98(4):1171-1174. doi: 10.4269/ajtmh.17-0870. Epub 2018 Feb 8.
PMID: 29436343 F

Sunwen Chou, MD - Professor of Medicine

Kotton CN, Kumar D, Caliendo AM, Huprikar S, Chou S, Danziger-Isakov L, Humar A. The third international consensus guidelines on the management of cytomegalovirus in solid organ transplantation. Transplantation. DOI: 10.1097/TP.0000000000002191

Chou S, Satterwhite LE, Ercolani RJ. New locus of drug resistance in the human cytomegalovirus UL56 gene revealed by in vitro exposure to letermovir and ganciclovir.  Antimicrobial Agents and Chemotherapy. DOI: 10.1128/AAC.00922-18

Chou S, Ercolani RJ, Derakhchan K. Antiviral activity of maribavir in combination with other drugs active against human cytomegalovirus.  Antiviral Research. DOI: 10.1016/j.antiviral.2018.07.013

Cherrier L, Nasar A Goodlet KJ, Nailor MD, Tokman S, Chou S. Emergence of letermovir resistance in a lung transplant recipient with ganciclovir-resistant cytomegalovirus infection.  American Journal of Transplantation. DOI: 10.1111/ajt.15135

J. Stone Doggett, MD - Assistant Professor of Medicine

McConnell EV, Bruzual I, Pou S, Winter R, Dodean RA, Smilkstein MJ, Krollenbrock A, Nilsen A, Zakharov LN, Riscoe MK, Doggett JS. Targeted Structure-Activity Analysis of Endochin-like Quinolones Reveals Potent Qi and Qo Site Inhibitors of Toxoplasma gondii and Plasmodium falciparum Cytochrome bc1 and Identifies ELQ-400 as a Remarkably Effective Compound against Acute Experimental Toxoplasmosis. ACS Infect Dis. 2018 Nov 9;4(11):1574-1584. doi: 10.1021/acsinfecdis.8b00133. Epub 2018 Aug 30. PMID: 30117728; PMCID: PMC6884402.
https://pubmed.ncbi.nlm.nih.gov/30117728/

Kirkman LA, Zhan W, Visone J, Dziedziech A, Singh PK, Fan H, Tong X, Bruzual I, Hara R, Kawasaki M, Imaeda T, Okamoto R, Sato K, Michino M, Alvaro EF, Guiang LF, Sanz L, Mota DJ, Govindasamy K, Wang R, Ling Y, Tumwebaze PK, Sukenick G, Shi L, Vendome J, Bhanot P, Rosenthal PJ, Aso K, Foley MA, Cooper RA, Kafsack B, Doggett JS, Nathan CF, Lin G. Antimalarial proteasome inhibitor reveals collateral sensitivity from intersubunit interactions and fitness cost of resistance. Proc Natl Acad Sci U S A. 2018 Jul 17;115(29):E6863-E6870. doi: 10.1073/pnas.1806109115. Epub 2018 Jul 2. PMID: 29967165; PMCID: PMC6055138.
https://pubmed.ncbi.nlm.nih.gov/29967165/

Morgan Hakki, MD - Associate Professor of Medicine

Hakki M, Lewis JS II. Ceftolozane-tazobactam therapy for multidrug-resistant Pseudomonas aeruginosa infections in patients with hematologic malignancies and hematpoeitic-cell transplant recipients. Infection.  https://pubmed.ncbi.nlm.nih.gov/29460229/

Noah McKittrick, MD - Assistant Professor of Medicine

McKittrick N, LaBeaud AD. “Chapter 69: Fever in the Returned Traveler.” Pediatric Infectious Diseases: Essentials for Practice, 2nd Edition. SS Shah, AJ Ratner, AR Kemper, Eds. New York: McGraw-Hill, 2018. 617-625.

Bill Messer, MD, PhD - Assistant Professor of Medicine

Li SK, Messer WB. Burkholderia cepacia complex Cervical Osteomyelitis in an Intravenous Drug User. Case Rep Infect Dis. 2018;2018:7638639. Epub 2018/10/03. doi: 10.1155/2018/7638639. PubMed PMID: 30271645; PMCID: PMC6151243.

Leier HC, Messer WB, Tafesse FG. Lipids and pathogenic flaviviruses: An intimate union. PLoS Pathog. 2018;14(5):e1006952. Epub 2018/05/11. doi: 10.1371/journal.ppat.1006952. PubMed PMID: 29746606; PMCID: PMC5944919.

Monica Sikka, MD - Assistant Professor of Medicine

Wenzler E, Bleasdale SC, Sikka M, Bunnell KL, Finnemeyer M, Rosenkranz SL, Danziger LH, Rodvold KA; Antibacterial Resistance Leadership Group. Phase I Study to Evaluate the Pharmacokinetics, Safety, and Tolerability of Two Dosing Regimens of Oral Fosfomycin Tromethamine in Healthy Adult Participants. Antimicrobial Agents and Chemotherapy.  https://doi.org/10.1128/AAC.00464-18

Bunnell KL, Pai, MP, Sikka M, Bleasdale, S, Wenzler E, Danziger LH, Rodvold KA. Pharmacokinectics of Telavancin at Fixed Doses in Normal-Body-Weight and Obese (Classes I,II, and III, Adult Subjects. Antimicrobial Agents and Chemotherapy.  https://doi.org/10.1128/AAC.02475-17

Luke Strnad, MD - Assistant Professor of Medicine

Strnad L, Winthrop KL. Treatment of Mycobacterium abscessus Complex. Semin Respir Crit Care Med.  https://pubmed.ncbi.nlm.nih.gov/30071551/

Farr K, Ravindran R, Strnad L, Chang E, Chaisson LH, Yoon C, Worodria W, Andama A, Ayakaka I, Bbosa Nalwanga P, Byanyima P, Kalema N, Kaswabuli S, Katagira W, Aman KD, Musisi E, Tumwine NW, Sanyu I, Ssebunya R, Davis JL, Huang L, Khan IH, Cattamanchi A. Diagnostic performance of blood inflammatory markers for tuberculosis screening in people living with HIV. PLoS One.  https://pubmed.ncbi.nlm.nih.gov/30352099/

Book Chapter: Katie Raffel and Luke Strnad. Infectious Diseases. First Aid for the Internal Medicine Boards, 4th Edition, ed by Le et al.

Sunwen Chou, MD - Professor of Medicine

Chemaly RF, Chou S, Einsele H, Griffiths P, Avery R, Razonable RR, Mullane KM, Kotton C, Lundgren J, Komatsu TE, Lischka P, Josephson F, Douglas CM, Umeh O, Miller V, Ljungman P. Definitions of resistant and refractory cytomegalovirus infection and disease in transplant recipients for use in clinical trials.  Clinical Infectious Diseases. DOI: 10.1093/cid/ciy696

Chou S, Wu J, Song K, Bo T. Novel UL97 drug resistance mutations identified at baseline in a clinical trial of maribavir for resistant or refractory cytomegalovirus infection.  Antiviral Research. DOI: 10.1016/j.antiviral.2019.104616

J. Stone Doggett, MD - Assistant Professor of Medicine

Hulverson MA, Bruzual I, McConnell EV, Huang W, Vidadala RSR, Choi R, Arnold SLM, Whitman GR, McCloskey MC, Barrett LK, Rivas KL, Scheele S, DeRocher AE, Parsons M, Ojo KK, Maly DJ, Fan E, Van Voorhis WC, Doggett JS. Pharmacokinetics and In Vivo Efficacy of Pyrazolopyrimidine, Pyrrolopyrimidine, and 5-Aminopyrazole-4-Carboxamide Bumped Kinase Inhibitors against Toxoplasmosis. J Infect Dis. 2019 Apr 16;219(9):1464-1473. doi: 10.1093/infdis/jiy664. PMID: 30423128; PMCID: PMC6467197.
https://pubmed.ncbi.nlm.nih.gov/30423128/

Morgan Hakki, MD - Associate Professor of Medicine

Petersen J, Lindner C, Hakki M. Incidence and outcomes of bacterial bloodstream infections during acute graft versus host disease involving the gastrointestinal tract following hematopoietic-cell transplant. Biol Blood Marrow Transplant. Selected for editorial commentary: “Intestinal Acute Graft-versus-Host Disease: A Bug Highway to the Bloodstream”. Horwitz M.E. Biol Blood Marrow Transplant.  https://pubmed.ncbi.nlm.nih.gov/31002988/

Hakki M, Humphries RM, Hamarajata P, Tallman GB, Shields RK, Mettus RT, Doi Y, Lewis JS II. Fluoroquinolone prophylaxis selects for meropenem non-susceptible Pseudomonas aeruginosa in patients with hematologic malignancies and hematopoietic-cell transplant recipients. Clinical Infectious Diseases.  https://pubmed.ncbi.nlm.nih.gov/30256922/

Noah McKittrick, MD - Assistant Professor of Medicine

Fenwick AJ, McKittrick N, Zhang SX. The Brief Case: Laryngeal Blastomycosis Involving a Vocal Cord Implant. Journal of Clinical Microbiology.  https://pubmed.ncbi.nlm.nih.gov/31645409/

McKittrick N, Malhotra IJ, Vu DM, et al. Parasitic infections during pregnancy need not affect infant antibody responses to early vaccination against Streptococcus pneumoniae, diphtheria, or Haemophilus influenzae type B. PLoS Neglected Tropical Diseases.  https://pubmed.ncbi.nlm.nih.gov/30818339/

Bill Messer, MD, PhD - Assistant Professor of Medicine

Kareko BW, Booty BL, Nix CD, Lyski ZL, Slifka MK, Amanna IJ, Messer WB. Persistence of Neutralizing Antibody Responses Among Yellow Fever Virus 17D Vaccinees Living in a Nonendemic Setting. J Infect Dis. 2019. Epub 2019/09/24. doi: 10.1093/infdis/jiz374. PubMed PMID: 31545367

Lyski ZL, Messer WB. Approaches to Interrogating the Human Memory B-Cell and Memory-Derived Antibody Repertoire Following Dengue Virus Infection. Front Immunol. 2019;10:1276. Epub 2019/06/28. doi: 10.3389/fimmu.2019.01276. PubMed PMID: 31244836; PMCID: PMC6562360.

Fontana L, Bonura E, Lyski Z, Messer W. The Brief Case: Klebsiella variicola-Identifying the Misidentified. J Clin Microbiol. 2019;57(1). Epub 2019/01/04. doi: 10.1128/JCM.00826-18. PubMed PMID: 30602547; PMCID: PMC6322460.

Fontana L, Bonura E, Lyski Z, Messer W. Closing the Brief Case: Klebsiella variicola-Identifying the Misidentified. J Clin Microbiol. 2019;57(1). Epub 2019/01/04. doi: 10.1128/JCM.00825-18. PubMed PMID: 30602546; PMCID: PMC6322464.

Monica Sikka, MD - Assistant Professor of Medicine

Oda G, Winters MA, Pacheco SM, Sikka MK, Bleasdale SC, Dunn B, Boswell E, Winters B, Bumsted A, Frisch J, Holodniy M. Clusters of nontuberculous mycobacteria linked to water sources at three Veterans Affairs medical centers. Infection Control & Hospital Epi.  https://doi.org/10.1017/ice.2019.342

Streifel AC, Sikka MK, Bowen CD, Lewis JS 2nd; Dalbavancin use in an academic medical center and associated cost-savings. Int J Antimicrob Agents.  https://doi.org/10.1016/j.ijantimicag.2019.08.007

Bleasdale SC, Sikka MK, Moritz DC, Fritzen-Pedicini C, Stiehl E, Brosseau LM, Jones RM. Experience of Chicagoland acute care hospitals in preparing for Ebola virus disease, 2014-2015. J Occup Environ Hyg.  https://doi.org/10.1080/15459624.2019.1628966

Luke Strnad, MD - Assistant Professor of Medicine

Liu C, Strnad L, Beekmann SE, Polgreen PM, Chambers HF. Clinical Practice Variation Among Adult Infectious Disease Physicians in the Management of Staphylococcus aureus Bacteremia. Clin Infect Dis.  https://pubmed.ncbi.nlm.nih.gov/30601989/

Tapper EB, Strnad L, Shmerling R. Reducing the Burden of False-Positive Tests: It Is Time to Optimize Diagnostic Testing for Undifferentiated Conditions. Mayo Clin Proc.  https://pubmed.ncbi.nlm.nih.gov/31272564/

Nathavitharana RR, Strnad L, Lederer PA, Shah M, Hurtado RM. Top Questions in the Diagnosis and Treatment of Pulmonary M. abscessus Disease. Open Forum Infect Dis.  https://pubmed.ncbi.nlm.nih.gov/31289727/

Shete PB, Farr K, Strnad L, Gray CM, Cattamanchi A. Diagnostic accuracy of TB-LAMP for pulmonary tuberculosis: a systematic review and meta-analysis. BMC Infect Dis.  https://pubmed.ncbi.nlm.nih.gov/30890135/

Book Chapter: Luke Strnad and Kevin Winthrop. Mycobacterium avium Complex. Mandell, Douglas, and Bennett's Principles and Practice of Infectious Diseases, 9th Edition, ed by Bennett et al.

Sunwen Chou, MD - Professor of Medicine

Douglas CM, Barnard R, Holder D, Leavitt R, Levitan D, Maguire M, Nickle D, Teal V, Wan H, van Alewijk D, van Doorn L, Chou S, Strizki J. Letermovir resistance analysis in a clinical trial of cytomegalovirus prophylaxis for hematopoietic stem cell transplant recipients.  Journal of Infectious Diseases. DOI: 10.1093/infdis/jiz577

Chou S. Advances in the genotypic diagnosis of cytomegalovirus antiviral drug resistance. Antiviral Research. DOI: 10.1016/j.antiviral.2020.104711

Chou S, Song K, Wu J, Bo T, Crumpacker C. Drug resistance mutations and associated phenotypes detected in clinical trials of maribavir for treatment of cytomegalovirus infection.  Journal of Infectious Diseases. DOI: 10.1093/infdis/jiaa462

J. Stone Doggett, MD - Assistant Professor of Medicine

Doggett JS, Schultz T, Miller AJ, Bruzual I, Pou S, Winter R, Dodean R, Zakharov LN, Nilsen A, Riscoe MK, Carruthers VB. Orally Bioavailable Endochin-like Quinolone Carbonate Ester Prodrug Reduces Toxoplasma gondii Brain Cysts. Antimicrob Agents Chemother. 2020 Jun 15:AAC.00535-20. doi:10.1128/AAC.00535-20. Epub ahead of print. PMID: 32540978. 
https://pubmed.ncbi.nlm.nih.gov/32540978/

Morgan Hakki, MD - Associate Professor of Medicine

Hakki M. Moving past ganciclovir and foscarnet: advances in CMV therapy. Current Hematol Malig Rep.  https://pubmed.ncbi.nlm.nih.gov/31981100/

Fontana L, Perlin DS, Zhao Y, Noble BN, Lewis JS II, Strasfeld L, Hakki M. Isavuconazole prophylaxis in patients with hematologic malignancies and hematopoietic-cell transplant recipients. Clin Infect Dis. Selected as one of “Top 10 papers in medical mycology – 2019” by the Mycoses Study Group Education and Research Consortium.  https://pubmed.ncbi.nlm.nih.gov/30958538/

Bill Messer, MD, PhD - Assistant Professor of Medicine

Nix CD, Salberg J, Coulter FJ, Kareko BW, Lyski ZL, Booty BL, Messer WB. Potency and breadth of human primary ZIKV immune sera shows that Zika viruses cluster antigenically as a single serotype. PLoS Negl Trop Dis. 2020 Apr;14(4):e0008006. doi: 10.1371/journal.pntd.0008006. eCollection 2020 Apr. PubMed PMID: 32282800.

Monica Sikka, MD - Assistant Professor of Medicine

Streifel, AC, Sikka MK. The Urgent Need for Medicare Reimbursement for Home Infusion Antibiotics amidst a Pandemic. Clin Infect Dis.  https://doi.org/10.1093/cid/ciaa658

Capizzi J, Leahy J, Wheelock H, Garcia J, Strnad L, Sikka M, Englander H, Thomas A, Korthuis PT, Menza TW. Population-based trends in hospitalizations due to injection drug use-related serious bacterial infections, Oregon, 2008 to 2018. PLoS One. 2020 Nov 9;15(11):e0242165. doi: 10.1371/journal.pone.0242165. PMID: 33166363.

Luke Strnad, MD - Assistant Professor of Medicine

Capizzi J, Leahy J, Wheelock H, Garcia J, Strnad L, Sikka M, Englander H, Thomas A, Korthuis PT, Menza TW. Population-based trends in hospitalizations due to injection drug use-related serious bacterial infections, Oregon, 2008 to 2018. PLoS One. 2020 Nov 9;15(11):e0242165. doi: 10.1371/journal.pone.0242165. PMID: 33166363.