Photo of Winston Chamberlain, M.D., Ph.D.

Winston Chamberlain M.D., Ph.D.

  • (503) 494-7674
    • Associate Professor of Ophthalmology School of Medicine
    • Casey Eye Institute School of Medicine
    • Ophthalmology School of Medicine

Dr. Chamberlain received his B.S. in biology from California Institute of Technology. He holds a Ph.D. in immunology and an M.D. from the University of Colorado Health Sciences Center. He is board certified in ophthalmology, and a member of the American Academy of Ophthalmology. His research interests include the outcomes of corneal transplant surgery with the femtosecond laser and DSAEK techniques, and inflammatory responses in the cornea.


  • B.S., California Institute of Technology, Pasadena California 1993
  • Ph.D., Medical Scientists Training Program, University of Colorado Health Sciences Center and National Jewish Hospital, Denver Colorado 2000
  • M.D., University of Colorado, School of Medicine, Denver Colorado 2002
  • Residency:

    • Ophthalmology, University of California, Irvine
  • Fellowship:

    • Cornea and refractive surgery, University of California, Irvine
  • Certifications:

    • American Board of Ophthalmology


  • "Descemet stripping automated endothelial keratoplasty after 2 previously rejected femtosecond laser-assisted keratoplasties" European Journal of Ophthalmology September 5 2013
  • "Femtosecond-assisted deep anterior lamellar keratoplasty using big-bubble technique in a cornea with 16 radial keratotomy incisions" Cornea February 2011
  • "Femtosecond laser-assisted keratoplasty" British Journal of Ophthalmology  2014
  • "Femtosecond laser-assisted keratoplasty in failed penetrating keratoplasty and globe trauma" Cornea December 2011
  • "Eye bank-prepared femtosecond laser-assisted automated descemet membrane endothelial grafts" Cornea April 7 2015
  • "Topical/mucosal delivery of sub-unit vaccines that stimulate the ocular mucosal immune system" Ocular Surface October 2006
  • "Nuclear entry, oligomerization, and DNA binding of the Drosophila heat shock transcription factor are regulated by a unique nuclear localization sequence" Genes and Development May 15 1997
  • "Functional subsets within clonally expanded CD8+ memory T cells in elderly humans" Clinical Immunology March 2000
  • "Genetic control of autoimmune myocarditis mediated by myosin-specific antibodies" Immunogenetics  1999
  • "Comparison of corneal surface higher-order aberrations after endothelial keratoplasty, femtosecond laser-assisted keratoplasty, and conventional penetrating keratoplasty" Cornea January 1 2012
  • "Imaging and quantification of endothelial cell loss in eye bank prepared DMEK grafts using trainable segmentation software" Current Eye Research  2014
  • "Large clonal CD8+ T cell expansions in elderly humans display a dichotomy of differentiated states that reflect a response to persistent antigen" Journal of Investigative Medicine February 1999
  • "Transcription of the FMR1 gene in individuals with fragile X syndrome" American Journal of Medical Genetics, Part A  2000
  • "September consultation #3" Journal of Cataract and Refractive Surgery September 2011
  • "Association of central corneal thickness and 24-hour intraocular pressure fluctuation" Journal of Glaucoma March 2008
  • "Comparison of Penetrating Keratoplasty Performed with a Femtosecond Laser Zig-Zag Incision versus Conventional Blade Trephination" Ophthalmology September 2009
  • "Laboratory evaluation of femtosecond laser lamellar cuts in gamma-irradiated corneas" Cornea October 9 2015
  • "Comparison of femtosecond laser-assisted keratoplasty versus conventional penetrating keratoplasty" Ophthalmology March 2011
  • "Erratum" Immunogenetics  1999
  • "Nasolacrimal duct closure modulates ocular mucosal and systemic CD4 + T-cell responses induced following topical ocular or intranasal immunization" Clinical and Vaccine Immunology March 2010
  • "Subclinical keratoconus detection by pattern analysis of corneal and epithelial thickness maps with optical coherence tomography" Journal of Cataract and Refractive Surgery February 1 2016
  • "Quantification and patterns of endothelial cell loss due to eye bank preparation and injector method in descemet membrane endothelial keratoplasty tissues" Cornea  2016
  • "Deep Laser-Assisted Lamellar Anterior Keratoplasty with Microkeratome-Cut Grafts" Cornea  2016
  • "Differentiating keratoconus and corneal warpage by analyzing focal change patterns in corneal topography, pachymetry, and epithelial thickness maps" Investigative Ophthalmology and Visual Science July 1 2016
  • "Selecting fuchs patients for drug trials involving endothelial cell proliferation" European Journal of Ophthalmology November 1 2016
  • "Distinguishing between contact lens warpage and ectasia" Journal of Cataract and Refractive Surgery January 1 2017
  • "Transmission of donor-derived breast carcinoma as a recurrent mass in a keratolimbal allograft" Cornea  2017
  • "Guiding flying-spot laser transepithelial phototherapeutic keratectomy with optical coherence tomography" Journal of Cataract and Refractive Surgery April 1 2017
  • "Clinic Workflow Simulations using Secondary EHR Data" AMIA ... Annual Symposium proceedings / AMIA Symposium. AMIA Symposium  2016
  • "Time requirements for electronic health record use in an academic ophthalmology center" JAMA Ophthalmology November 1 2017

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