Photo of Ted S. Acott, Ph.D.

Ted S. Acott Ph.D.

    • Research Professor of Ophthalmology School of Medicine
    • Ophthalmology School of Medicine
    • Program in Molecular and Cellular Biosciences School of Medicine
    • Biochemistry and Molecular Biology Graduate Program School of Medicine

Publications

  • "Consensus recommendations for trabecular meshwork cell isolation, characterization and culture." Experimental Eye Research  In: , Vol. 171, 01.06.2018, p. 164-173.
  • "Biomechanical rigidity and quantitative proteomics analysis of segmental regions of the trabecular meshwork at physiologic and elevated pressures." Investigative Ophthalmology and Visual Science  In: , Vol. 59, No. 1, 01.01.2018, p. 246-259.
  • "Glaucomatous cell derived matrices differentially modulate non-glaucomatous trabecular meshwork cellular behavior." Acta Biomaterialia  In: , 01.01.2018.
  • "Tunneling nanotubes are novel cellular structures that communicate signals between trabecular meshwork cells." Investigative Ophthalmology and Visual Science In: , Vol. 58, No. 12, 01.10.2017, p. 5298-5307.
  • "Estimating human trabecular meshwork stiffness by numerical modeling and advanced OCT imaging." Investigative Ophthalmology and Visual Science  In: , Vol. 58, No. 11, 01.09.2017, p. 4809-4817.
  • "Effects of induction and inhibition of matrix cross-linking on remodeling of the aqueous outflow resistance by ocular trabecular meshwork cells." Scientific Reports In: , Vol. 6, 30505, 28.07.2016.
  • "Pressure-induced expression changes in segmental flow regions of the human trabecular meshwork." Experimental Eye Research In: , 15.03.2016.
  • "Extracellular matrix in the trabecular meshwork : Intraocular pressure regulation and dysregulation in glaucoma." Experimental Eye Research In: , Vol. 133, 01.04.2015, p. 112-125.
  • "Mapping molecular differences and extracellular matrix gene expression in segmental outflow pathways of the human ocular trabecular meshwork." PLoS One In: , Vol. 10, No. 3, e0122483, 31.03.2015.
  • "Induced pluripotent stem cells restore function in a human cell loss model of open-angle glaucoma." Stem Cells In: , Vol. 33, No. 3, 01.03.2015, p. 751-761.
  • "Interleukin-20 receptor expression in the trabecular meshwork and its implication in glaucoma." Journal of Ocular Pharmacology and Therapeutics In: , Vol. 30, No. 2-3, 01.03.2014, p. 267-276.
  • "Intraocular pressure homeostasis : Maintaining balance in a high-pressure environment." Journal of Ocular Pharmacology and Therapeutics In: , Vol. 30, No. 2-3, 01.03.2014, p. 94-101.
  • "Differential effects of caveolin-1 and -2 knockdown on aqueous outflow and altered extracellular matrix turnover in caveolin-silenced trabecular meshwork cells." Investigative Ophthalmology and Visual Science In: , Vol. 55, No. 9, 2014, p. 5497-5509.
  • "Ankyrin repeat and suppressor of cytokine signaling box containing protein-10 is associated with ubiquitin-mediated degradation pathways in trabecular meshwork cells." Molecular Vision In: , Vol. 19, 25.07.2013, p. 1639-1655.
  • "The effects of tenascin C knockdown on trabecular meshwork outflow resistance." Investigative Ophthalmology and Visual Science In: , Vol. 54, No. 8, 2013, p. 5613-5623.
  • "Inhibition of Hyaluronan Synthesis Reduces Versican and Fibronectin Levels in Trabecular Meshwork Cells." PLoS One In: , Vol. 7, No. 11, e48523, 05.11.2012.
  • "Perturbation of hyaluronan synthesis in the trabecular meshwork and the effects on outflow facility." Investigative Ophthalmology and Visual Science In: , Vol. 53, No. 8, 07.2012, p. 4616-4625.
  • "Current understanding of conventional outflow dysfunction in glaucoma." Current Opinion in Ophthalmology In: , Vol. 23, No. 2, 03.2012, p. 135-143.
  • "Variants in ASB10 are associated with open-angle glaucoma." Human Molecular Genetics In: , Vol. 21, No. 6, ddr572, 03.2012, p. 1336-1349.
  • "Molecular chaperone function for myocilin." Investigative Ophthalmology and Visual Science In: , Vol. 52, No. 10, 09.2011, p. 7548-7555.
  • "Segmental versican expression in the trabecular meshwork and involvement in outflow facility." Investigative Ophthalmology and Visual Science In: , Vol. 52, No. 8, 07.2011, p. 5049-5057.
  • "Elastic modulus determination of normal and glaucomatous human trabecular meshwork." Investigative Ophthalmology and Visual Science  In: , Vol. 52, No. 5, 04.2011, p. 2147-2152.
  • "Differential effects of ADAMTS-1, -4, and -5 in the trabecular meshwork." Investigative Ophthalmology and Visual Science In: , Vol. 50, No. 12, 12.2009, p. 5769-5777.
  • "Stem cells in the trabecular meshwork : Present and future promises." Experimental Eye Research In: , Vol. 88, No. 4, 30.04.2009, p. 747-751.
  • "Extracellular matrix turnover and outflow resistance." Experimental Eye Research In: , Vol. 88, No. 4, 30.04.2009, p. 676-682.
  • "Effects of modifiers of glycosaminoglycan biosynthesis on outflow facility in perfusion culture." Investigative Ophthalmology and Visual Science In: , Vol. 49, No. 6, 06.2008, p. 2495-2505.
  • "Extracellular matrix in the trabecular meshwork." Experimental Eye Research In: , Vol. 86, No. 4, 04.2008, p. 543-561.
  • "Specialized podosome-or invadopodia-like structures (PILS) for focal trabecular meshwork extracellular matrix turnover." Investigative Ophthalmology and Visual Science In: , Vol. 49, No. 12, 2008, p. 5353-5365.
  • "Identification of novel alternatively spliced isoforms of RTEF-1 within human ocular vascular endothelial cells and murine retina." Investigative Ophthalmology and Visual Science  In: , Vol. 48, No. 8, 08.2007, p. 3775-3782.
  • "p38 MAP kinase pathway and stromelysin regulation in trabecular meshwork cells." Investigative Ophthalmology and Visual Science In: , Vol. 48, No. 7, 07.2007, p. 3126-3137.

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