Photo of Sergio Fazio, M.D., Ph.D.

Sergio Fazio M.D., Ph.D.

M.D., University of Rome, Rome, Italy
Ph.D., Experimental medicine, University of Siena, Siena, Italy and University of California, San Francisco

Education

  • M.D., University of Rome, Rome Italy 1983
  • Ph.D., University of California, San Francisco California 1989
  • Residency:

    • Internal Medicine, University of Rome, Rome, Italy
  • Fellowship:

    • Metabolism, University of Rome, Italy and University of California, San Francisco
  • Certifications:

    • American Board of Clinical Lipidology

Publications

  • "The role of PCSK9 in intestinal lipoprotein metabolism" Atherosclerosis Supplements February 1 2015
  • "Peeking into a cool future" Circulation Research August 15 2014
  • "Physiological relevance of apolipoprotein E recycling" Metabolism: Clinical and Experimental October 2005
  • "Adipocyte fatty acid-binding protein, aP2, alters late atherosclerotic lesion formation in severe hypercholesterolemia" Arteriosclerosis, Thrombosis, and Vascular Biology October 1 2002
  • "Metabolic Syndrome and the Risk of Cardiovascular Disease in Older Adults" Journal of the American College of Cardiology April 18 2006
  • "The recycling of apolipoprotein E in primary cultures of mouse hepatocytes" Journal of Biological Chemistry March 14 2003
  • "Reduced macrophage apoptosis is associated with accelerated atherosclerosis in low-density lipoprotein receptor-null mice" Arteriosclerosis, Thrombosis, and Vascular Biology January 2005
  • "Lipoprotein subclasses determined by nuclear magnetic resonance spectroscopy and coronary atherosclerosis in patients with rheumatoid arthritis" Journal of Rheumatology August 2010
  • "Isolevuglandin-type lipid aldehydes induce the inflammatory response of macrophages by modifying phosphatidylethanolamines and activating the receptor for advanced glycation endproducts" Antioxidants and Redox Signaling June 20 2015
  • "Cytoplasmic fatty acid-binding proteins" Current Opinion in Lipidology  2002
  • "Hepatic apo E expression is required for remnant lipoprotein clearance in the absence of the low density lipoprotein receptor" Journal of Clinical Investigation April 15 1998
  • "HDL" Biochimica Clinica February 2012
  • "Correlates of high serum C-reactive protein levels in a socioeconomically disadvantaged population" Disease Markers  2008
  • "Editorial introductions" Current Opinion in Lipidology August 2007
  • "Lifestyle determinants of c-reactive protein in middle-aged, urban Chinese men" Nutrition, Metabolism and Cardiovascular Diseases March 2012
  • "Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in vivo" Journal of Clinical Investigation June 1999
  • "Unique pathway for cholesterol uptake in fat cells" Arteriosclerosis, Thrombosis, and Vascular Biology September 2004
  • "Interplay between apolipoprotein E and scavenger receptor class B type I controls coronary atherosclerosis and lifespan in the mouse" Circulation June 28 2005
  • "Quantitative estimates of the variability of in vivo sonographic measurements of the mouse aorta for studies of abdominal aortic aneurysms and related arterial diseases" Journal of Ultrasound in Medicine June 1 2011
  • "Impaired secretion of apolipoprotein E2 from macrophages" Journal of Biological Chemistry May 4 2007
  • "Re-emergence of fibrates in the management of dyslipidemia and cardiovascular risk." Current Atherosclerosis Reports January 2000
  • "Purine-rich foods, protein intake, and the prevalence of hyperuricemia" Nutrition, Metabolism and Cardiovascular Diseases May 2012
  • "Recent insights into the pathogenesis of type III hyperlipoproteinemia" Trends in Cardiovascular Medicine  1993
  • "Dyslipidemias in children" Pediatric Annals February 2012
  • "Reduced ABCA1-mediated cholesterol efflux and accelerated atherosclerosis in apolipoprotein E-deficient mice lacking macrophage-derived ACAT1" Circulation May 10 2005
  • "Proprotein convertase subtilisin/kexin type 9 as transducer of physiologic influences on cellular cholesterol" Journal of the American College of Cardiology May 8 2012
  • "Class A scavenger receptors, macrophages, and atherosclerosis" Current Opinion in Lipidology  2001
  • "Accumulation of Human Apolipoprotein-E in Rat Plasma After in vivo Intramuscular Injection of Naked DNA" Biochemical and Biophysical Research Communications April 15 1994
  • "Long-Term Safety and Efficacy of Triple Combination Ezetimibe/Simvastatin Plus Extended-Release Niacin in Patients With Hyperlipidemia" American Journal of Cardiology February 15 2010
  • "ACAT inhibition" Arteriosclerosis, Thrombosis, and Vascular Biology January 2005

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