Photo of Sergio Fazio, M.D., Ph.D.

Sergio Fazio M.D., Ph.D.

M.D., University of Rome, Rome, Italy
Ph.D., Experimental medicine, University of Siena, Siena, Italy and University of California, San Francisco


  • M.D., University of Rome, Rome Italy 1983
  • Ph.D., University of California, San Francisco California 1989
  • Residency:

    • Internal Medicine, University of Rome, Rome, Italy
  • Fellowship:

    • Metabolism, University of Rome, Italy and University of California, San Francisco
  • Certifications:

    • American Board of Clinical Lipidology


  • "The role of PCSK9 in intestinal lipoprotein metabolism" Atherosclerosis Supplements February 1 2015
  • "Peeking into a cool future" Circulation Research August 15 2014
  • "Physiological relevance of apolipoprotein E recycling" Metabolism: Clinical and Experimental October 2005
  • "Adipocyte fatty acid-binding protein, aP2, alters late atherosclerotic lesion formation in severe hypercholesterolemia" Arteriosclerosis, Thrombosis, and Vascular Biology October 1 2002
  • "Metabolic Syndrome and the Risk of Cardiovascular Disease in Older Adults" Journal of the American College of Cardiology April 18 2006
  • "The recycling of apolipoprotein E in primary cultures of mouse hepatocytes" Journal of Biological Chemistry March 14 2003
  • "Reduced macrophage apoptosis is associated with accelerated atherosclerosis in low-density lipoprotein receptor-null mice" Arteriosclerosis, Thrombosis, and Vascular Biology January 2005
  • "Lipoprotein subclasses determined by nuclear magnetic resonance spectroscopy and coronary atherosclerosis in patients with rheumatoid arthritis" Journal of Rheumatology August 2010
  • "Isolevuglandin-type lipid aldehydes induce the inflammatory response of macrophages by modifying phosphatidylethanolamines and activating the receptor for advanced glycation endproducts" Antioxidants and Redox Signaling June 20 2015
  • "Cytoplasmic fatty acid-binding proteins" Current Opinion in Lipidology  2002
  • "Hepatic apo E expression is required for remnant lipoprotein clearance in the absence of the low density lipoprotein receptor" Journal of Clinical Investigation April 15 1998
  • "HDL" Biochimica Clinica February 2012
  • "Correlates of high serum C-reactive protein levels in a socioeconomically disadvantaged population" Disease Markers  2008
  • "Editorial introductions" Current Opinion in Lipidology August 2007
  • "Lifestyle determinants of c-reactive protein in middle-aged, urban Chinese men" Nutrition, Metabolism and Cardiovascular Diseases March 2012
  • "Macrophage lipoprotein lipase promotes foam cell formation and atherosclerosis in vivo" Journal of Clinical Investigation June 1999
  • "Unique pathway for cholesterol uptake in fat cells" Arteriosclerosis, Thrombosis, and Vascular Biology September 2004
  • "Interplay between apolipoprotein E and scavenger receptor class B type I controls coronary atherosclerosis and lifespan in the mouse" Circulation June 28 2005
  • "Quantitative estimates of the variability of in vivo sonographic measurements of the mouse aorta for studies of abdominal aortic aneurysms and related arterial diseases" Journal of Ultrasound in Medicine June 1 2011
  • "Impaired secretion of apolipoprotein E2 from macrophages" Journal of Biological Chemistry May 4 2007
  • "Re-emergence of fibrates in the management of dyslipidemia and cardiovascular risk." Current Atherosclerosis Reports January 2000
  • "Purine-rich foods, protein intake, and the prevalence of hyperuricemia" Nutrition, Metabolism and Cardiovascular Diseases May 2012
  • "Recent insights into the pathogenesis of type III hyperlipoproteinemia" Trends in Cardiovascular Medicine  1993
  • "Dyslipidemias in children" Pediatric Annals February 2012
  • "Reduced ABCA1-mediated cholesterol efflux and accelerated atherosclerosis in apolipoprotein E-deficient mice lacking macrophage-derived ACAT1" Circulation May 10 2005
  • "Proprotein convertase subtilisin/kexin type 9 as transducer of physiologic influences on cellular cholesterol" Journal of the American College of Cardiology May 8 2012
  • "Class A scavenger receptors, macrophages, and atherosclerosis" Current Opinion in Lipidology  2001
  • "Accumulation of Human Apolipoprotein-E in Rat Plasma After in vivo Intramuscular Injection of Naked DNA" Biochemical and Biophysical Research Communications April 15 1994
  • "Long-Term Safety and Efficacy of Triple Combination Ezetimibe/Simvastatin Plus Extended-Release Niacin in Patients With Hyperlipidemia" American Journal of Cardiology February 15 2010
  • "ACAT inhibition" Arteriosclerosis, Thrombosis, and Vascular Biology January 2005

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